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Rats confronted with the onset of a light gradient display a transient increase in locomotion called theactivity response (AR) and a dark preference (Godsil & Fanselow, 2004). These experiments demonstrate that the magnitude of the AR can be blunted
with Pavlovian fear-conditioning procedures via associative and nonassociative fear. Although manifested in decreased locomotion,
the blunted AR effect was not due to increased freezing or immobility behaviors. Instead, rats displayed reduced rearing and
an increase in a class of behaviors calledstationary activity. These results suggest that the lighting differential supplied by the cue influences the topography of defensive behavior
and reduces the expression of freezing. This procedure provides a means by which to examine learned and unlearned defensive
responses to the same stimulus. 相似文献
874.
Kavita Shalia Sudha Savant Vijaya A. Haldankar Tulip Nandu Poonam Pawar Siddhi Divekar V. K. Shah Purvi Bhatt 《Indian journal of clinical biochemistry : IJCB》2012,27(1):74-82
To analyse the association of high sensitivity C-reactive (hsCRP) protein levels and −717A/G single nucleotide polymorphism
of CRP with acute myocardial infarction (AMI) in the Indian population. Study population included 100 MI cases wherein 32
patients had experienced previous MI (MI-Group-1), 68 MI cases were recruited at presentation (MI-Group-2) and equal number
of age and gender matched healthy individuals. hsCRP levels were determined by ELISA and genotyping of −717A/G was carried
out by polymerase chain reaction-based restriction digestion method. The −717A/G genotypes did not influence hsCRP level and
their distribution did not differ between groups. However, in the present study hsCRP demonstrated significant correlation
with BMI in controls of both the genders and with triglycerides in females of AMI at presentation who otherwise are with low
risk profile. Identifying traditional risk factors associated with inflammation may help in controlling the acute event. 相似文献
875.
Meera S. Ghadge Purva P. Naik Bijaynath P. Tiwari Ruprekha M. Hegde Tanaji J. Matale 《Indian journal of clinical biochemistry : IJCB》2012,27(1):97-99
Breast cancer is one of the most frequent malignancies in the world. Available staging procedures to detect breast cancer
are bone scan, chest X-ray, liver ultrasonography, computerized tomography, estimation of tumor markers like carbohydrate
antigen (CA15-3) and carcino embryonic antigen. These procedures are expensive and may not be required in all cases. Out of
70 patients studied, 55 had normal CA15-3 and 15 had elevated levels of Ca15-3. Eight (14.5%) of the 55 patients with normal
CA15-3 had abnormal bone scan. Fifteen patients had CA15-3 levels above the normal range and among these 9 (60%) had abnormal
bone scan. While prime facie it would appear that a high level of CA15-3 correlate with abnormal bone scan, it is also true
that the numbers are small at present and conclusions about the validity of CA15-3 as marker of bone metastasis may be premature. 相似文献
876.
Yong Huo 《Journal of Zhejiang University. Science. B》2010,11(8):631-633
##正##Dr.Gruntzig et al.(1979) successfully completed the world's first percutaneous coronary intervention (PCI),a percutaneous transluminal coronary 相似文献
877.
Ling Xia Ying-lan Gong Xiu-wei Zhu Yu Zhang Qi Sun Heng-gui Zhang 《Journal of Zhejiang University. Science. B》2010,11(6):402-416
The aim of this study is to build two mathematical models of canine ionic currents specific to right atria and left atria.The canine left atria mathematical model was firstly modified from the Ramirez-Nattel-Courtemanche(RNC) model using the recently available experimental data of ionic currents and was further developed based on our own experimental data.A model of right atria was then built by considering the differences between right atria and left atria.The two developed models well reproduced the exper... 相似文献
878.
Qing-jun Liu Wei-wei Ye Hui Yu Ning Hu Li-ping Du Ping Wang 《Journal of Zhejiang University. Science. B》2010,11(5):323-331
Neurochip based on light-addressable potentiometric sensor(LAPS),whose sensing elements are excitable cells,can monitor electrophysiological properties of cultured neuron networks with cellular signals well analyzed.Here we report a kind of neurochip with rat pheochromocytoma(PC12) cells hybrid with LAPS and a method of de-noising signals based on wavelet transform.Cells were cultured on LAPS for several days to form networks,and we then used LAPS system to detect the extracellular potentials with signals d... 相似文献
879.
Su Ye Sohn Gi Young Jang Byung Min Choi 《Journal of Zhejiang University. Science. B》2010,11(7):539-541
Congenital atresia of the left main coronary artery is a rare occurrence, and surgical revascularizationbypass graft is required.
We here report a rare case of congenital coronary anomaly in an infant. A 10-month-old male infant was admitted to the hospital
with heart failure symptoms. Echocardiographic examinations revealed mitral valve regurgitation and ischemic changes of the
anterolateral papillary muscle and chordae. Coronary angiography showed atresia of the left main coronary artery with a severe
hypoplastic left anterior descending artery and a circumflex coronary artery. Unfortunately, sudden cardiac arrest occurred
after catheterization and the infant did not recover despite of immediate cardiopulmonary resuscitation. Further studies are
needed to find a newer diagnostic method to detect coronary anomaly in an infant, and coronary angiography, if necessary,
has to be performed very carefully. 相似文献
880.
This paper reports on the electromagnetic effects on the biological tissue surrounding a transcutaneous transformer for an
artificial anal sphincter. The coupling coils and human tissues, including the skin, fat, muscle, liver, and blood, were considered.
Specific absorption rate (SAR) and current density were analyzed by a finite-length solenoid model. First, SAR and current
density as a function of frequency (10–107 Hz) for an emission current of 1.5 A were calculated under different tissue thickness. Then relations between SAR, current
density, and five types of tissues under each frequency were deduced. As a result, both the SAR and current density were below
the basic restrictions of the International Commission on Non-Ionizing Radiation Protection (ICNIRP). The results show that
the analysis of these data is very important for developing the artificial anal sphincter system. 相似文献