Modulating chemotaxis of lung cancer cells by using electric fields in a microfluidic device

We employed direct-current electric fields (dcEFs) to modulate the chemotaxis of lung cancer cells in a microfluidic cell culture device that incorporates both stable concentration gradients and dcEFs. We found that the chemotaxis induced by a 0.5 μM/mm concentration gradient of epidermal growth factor can be nearly compensated by a 360 mV/mm dcEF. When the effect of chemical stimulation was balanced by the electrical drive, the cells migrated randomly, and the path lengths were largely reduced. We also demonstrated electrically modulated chemotaxis of two types of lung cancer cells with opposite directions of electrotaxis in this device.     

拳击、散打、跆拳道等速肌力测试比较研究

文章运用等速肌力测试的方法,对散打、拳击、跆拳道三项目32名男子散打运动员进行比较研究,发现散打运动员左肘伸肌绝对力量和速度力量明显大于拳击和跆拳道项目运动员;左肘屈肌绝对力量和速度力量又明显小于拳击项目运动员;右肘屈肌绝对力量拳击项目运动员明显大于散打项目运动员;右肘伸肌绝对力量有大于散打项目运动员的趋势;散打运动员右肘伸肌速度力量明显大于拳击和跆拳道项目运动员;右肘屈肌速度力量又明显小于其它两项目,但收缩速度优于其它两项目运动员;左膝屈肌速度力量跆拳道项目明显优于散打项目运动员。     

K-12 teachers’ perceptions of and their satisfaction with interaction type in blended learning environments

Blended learning is an effective approach to instruction that combines features of face-to-face learning and computer-mediated learning. This study investigated the relationship between student perceptions of three types of interaction and blended learning course satisfaction. The participants included K-12 teachers enrolled in a graduate-level course. Results indicate that students (a) perceived interaction as important to their learning experiences and (b) were moderately satisfied in their blended learning course. The predictive model of student satisfaction including three types of interaction was reliable. Of the three types of interaction, learner–content interaction was the strongest predictor of student satisfaction when the course design involved a low amount of collaborative activities. Additionally, student personality was found to be a vital factor for interaction and satisfaction in this type of course design. Students who reported having an extroverted personality noted more interaction and a higher level of student satisfaction than those who self-reported as introverted.     

季布故事的变更与发展--兼论《捉季布传文》对《史记》中季布故事的拓展

敦煌本《捉季布传文》的故事原型来自《史记》、《汉书》中的季布故事,其情节更加完善,人物更加丰满,不仅一改汉代史传文学简略质朴的叙事风格,而且整体变化尤为明显。文章通过探讨《捉季布传文》对《史记》中季布故事的拓展,探究了唐代俗文学的创作视角。     

Therapeutic potential of traditional Chinese medicine for vascular endothelial growth factor

Vascular endothelial growth factor (VEGF) is the main regulator of physiological angiogenesis during embryonic development, bone growth, and reproductive function, and it also participates in a series of pathological changes. Traditional Chinese medicine (TCM), with a history of more than 2000 years, has been widely used in clinical practice, while the exploration of its mechanisms has only begun. This review summarizes the research of recent years on the influence of TCM on VEGF. It is found that many Chinese medicines and recipes have a regulatory effect on VEGF, indicating that Chinese medicine has broad prospects as a complementary and alternative therapy, providing new treatment ideas for clinical applications and the theoretical basis for research on the mechanisms of TCM.