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151.
Denov MS 《Child abuse & neglect》2003,27(1):47-61
OBJECTIVE: To explore the experiences of victims of female sex offenders with regard to disclosing sexual abuse to a professional, and importantly, the impact of professional responses on victims. METHOD: The data were derived from one-to-one semi-structured interviews with 14 (7 males, 7 females) victims of child sexual abuse by female perpetrators. Victims ranged in age from 23 to 59 years and were recruited through professional referrals or through poster advertisements in counseling services. Participants responded to questions on their family background, experience(s) of sexual abuse, experience(s) disclosing the sexual abuse to a professional, and the impact of professional responses. RESULTS: The majority of victims reported sexual abuse by their mothers. The average age of onset of the sexual abuse was age 5, lasting, on average, 6 years. Five participants reported experiencing severe, moderate and mild sexual abuse, four reported experiencing both severe and mild sexual abuse and five reported experiencing moderate and mild sexual abuse. The findings underscore the significance of professional intervention in relation to victim disclosures of sexual abuse by females. Professional responses to disclosures, whether positive or negative, appeared to have a crucial impact on the well-being of victims. Supportive professional responses including the acknowledgment and validation of victims' experiences of sexual abuse appeared to mitigate the negative effects of the abuse. In contrast, unsupportive responses where professionals minimized, or disbelieved victims' allegations of sexual abuse appeared to exacerbate the negative effects of the sexual abuse, ultimately inciting secondary victimization. CONCLUSION: The study highlights the need for the development and implementation of professional training initiatives to sensitize professionals to the issue of female sex offending and the intervention needs of victims. Failure to do so could have negative consequences for victims sexually abused by females. 相似文献
152.
Avoiding almost entirely the depiction of poverty during prime‐time broadcasts, television networks present a sentimentalized vision of economic deprivation that omits or minimizes hardship while idealizing the supposed benefits of a spartan way of life. Much happier than the harried members of middle‐ and upper‐income groups, poor and working people on television seldom strive against their economic fates or against the system. Conclusions are based on a monitoring of prime‐time entertainment broadcast by the three commercial networks during “ratings month.” 相似文献
153.
Myriam Denguezli Imen Ben Chiekh Helmi Ben Saad Monia Zaouali-Ajina Zouhaier Tabka Abdelkrim Zbidi 《Journal of sports sciences》2013,31(12):1351-1359
Abstract The aim of this study was to determine whether endurance training in athletes induces airway inflammation and pulmonary function disorders. Respiratory pattern and function were analysed in ten healthy endurance runners at rest, during sub-maximal exercise, and during the recovery. Inflammatory cells and metabolites (histamine, interleukin-8, and leukotriene E4) were measured in sputum at rest and after exercise. The experiments were conducted on three different occasions (basic endurance training, pre-competitive and competitive periods). In spite of the absence of post-exercise spirometric changes and respiratory symptoms, airway cells counts and inflammatory markers changed significantly. At the beginning of the experiment, athletes' induced sputum showed an abundance of macrophages compared with neutrophils. We found a high percentage of neutrophils during the pre-competitive and competitive periods of the sport season (41% and 37%), a significant increase in macrophage counts during the pre-competitive period (51%), and a significant rise in total cells, interleukin-8, leukotriene E4, and histamine during the competitive period. In conclusion, one year's training increased markers of inflammation in the airways of endurance runners without symptoms or changes in pulmonary function, suggesting that airway inflammation is of insufficient magnitude to markedly impact lung function in healthy athletes. 相似文献
154.
Zuzana Svobodova Mohamad Reza Mohamadi Barbora Jankovicova Hermann Esselmann Romain Verpillot Markus Otto Myriam Taverna Jens Wiltfang Jean-Louis Viovy Zuzana Bilkova 《Biomicrofluidics》2012,6(2):024126-024126-12
Determination of amyloid β (Aβ) isoforms and in particular the proportion of the Aβ 1-42 isoform in cerebrospinal fluid (CSF) of patients suspected of Alzheimer’s disease might help in early diagnosis and treatment of that illness. Due to the low concentration of Aβ peptides in biological fluids, a preconcentration step prior to the detection step is often necessary. This study utilized on-chip immunoprecipitation, known as micro-immunoprecipitation (μIP). The technique uses an immunosorbent (IS) consisting of magnetic beads coated with specific anti-Aβ antibodies organized into an affinity microcolumn by a magnetic field. Our goal was to thoroughly describe the critical steps in developing the IS, such as selecting the proper beads and anti-Aβ antibodies, as well as optimizing the immobilization technique and μIP protocol. The latter includes selecting optimal elution conditions. Furthermore, we demonstrate the efficiency of anti-Aβ IS for μIP and specific capture of 5 Aβ peptides under optimized conditions using various subsequent analytical methods, including matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS), capillary electrophoresis, microchip electrophoresis, and immunoblotting. Synthetic Aβ peptides samples prepared in buffer and spiked in human CSF were analyzed. Finally, on-chip immunoprecipitation of Aβ peptides in human CSF sample was performed. 相似文献
155.
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157.
J G Jones H L Butler B Hamilton J D Perdue H P Stern R C Woody 《Child abuse & neglect》1986,10(1):33-40
Munchausen syndrome by proxy is a form of child abuse in which a disorder of the child is fabricated by a parent. Although often considered rare, it may have been overlooked frequently in the past. The reported cases of children with Munchausen syndrome by proxy range in age from infancy to 8 years. Their "illnesses" consist of fabricated histories, inflicted physical findings, altered laboratory specimens, and induced disorders. The perpetrator usually is the child's mother, who may have Munchausen syndrome. Consequences of the syndrome may include painful tests, frequent hospitalizations, potentially harmful treatment, and death. The diagnosis can be made when medical and social histories are characteristic of the syndrome and clinical findings are absent, suggestive of induced illness, or resolve upon separation of the child and parent. Suspicion of the syndrome should be discussed with the family once the safety of the child is insured, and the case should be reported under the child abuse reporting law of the state. Social, family, and medical histories must be obtained and verified, and court intervention should be considered. Four patients who illustrate typical features of the syndrome are described. 相似文献
158.
159.
R C Stern 《American annals of the deaf》1980,125(6):861-865
160.
This paper describes general curriculum design principles and specific software design implementations resulting from an ongoing collaboration between software designers and programmers, researchers, and a classroom teacher and his students. Research and observations in the classroom setting led to both the emergence of useful learning principles as well as the design of a specific piece of software, E-LabBook. The paper traces the development of the software in the context of the principles that emerged during the design process. 相似文献