Log-Linear Analysis: An Introduction for Researchers in Counseling

This article serves as an introduction to log-linear analysis, a technique used in the analysis of qualitative data arranged in multidimensional contingency tables. The steps involved in log-linear analysis are presented in the context of an investigation of a personality characteristic of a group of counselor trainees. The references cited and supplemental readings allow interested readers to pursue the topic further.     

Method evaluation of an enzymatic method for serum creatinine

Selecting the correct method for routine analysis by ‘method evaluation’ is an important component of quality assurance. It is a step-wise procedure that evaluates various analytical parameters like accuracy, precision etc of the given method. Finally reference intervals are established for selected population. We evaluated an enzymatic method for serum creatinine. The results show that it is an acceptable method based on the above mentioned criteria.     

Clinical usefulness of alterations in sialic acid,sialyl transferase and sialoproteins in breast cancer

Sialic acid, the end moieties of the carbohydrate chains are biologically important and essential for functions of glycoconjugates and are reported to be altered in cancer patients. Two hundred and twenty five breast cancer (BC) patients, 100 patients with benign breast disease (BBD) and 100 healthy females (controls) were enrolled for the study. Eight hundred and twenty four follow-up samples of 225 breast carcinoma patients were also evaluated. The association of sialic acid forms, sialyltransferase and α-2–6 sialoproteins levels with presence and extent as well as prognosis of breast carcinoma was studied. Serum sialic acid forms and sialyltransferase revealed significantly elevated levels among untreated breast cancer patients as compared to the controls, patients with BBD as well as cancer patients in remission. Non-responders showed comparable levels of the markers with those found in breast cancer patients at the time of diagnosis. Higher levels of sialic acid forms at diagnosis were associated with poor prognosis. A positive correlation between serum levels of different forms of sialic acids and extent of malignant disease was observed. The changes in serum proteins with terminal α-2–6 sialic acid correlated well with alterations in the levels of sialic acid forms and sialyltransferase. Malignant tissues showed elevated levels of sialic acid and sialyltransferase as compared to surrounding normal tissues. The results suggested potential utility of these markers in evaluation of clinical outcome.     

Effect of diabetic serum factor on polymorphonuclear leucocyte membrane hydrophobicity and particle internalisation

Membrane hydrophobicity and slalidase activity of normal Poly morphonuclear Leucocyte were significantly enhanced when incubated with DSF. As a consequence, internalisation ofE. coli andS. aureus (opsonised or unopsonised) were greatly dimnished, internalisation ofE. coli being higher in either category. Although, increase in hydrophobicity of the membrane correlated well with the time of decrease of particle internalisation (both at 30 min.), enhancement of sialidase activity did not coincide with the said alterations.     

The Semiconductor Chemical Sensor

Several methods of detecting the presence of various chemical species are considered. A specific example of atomic hydrogen in lead selenide is examined and used to illustrate some important principles.     

Prostate specific antigen in patients of benign prostate hypertrophy and carcinoma prostate

Prostate Specific Antigen (PSA) has emerged as the most applicable and important tumor marker for carcinoma prostate. In the present study PSA was determined in serum of healthy subjects, patients of benign prostate hypertrophy (BPH) and Carcinoma Prostate (Ca−P) to evaluate its diagnostic efficiency in day to day management of prostate cancer patients and in differentiating patients of early prostate cancer from those with BPH. Receiver operating characteristic curve (ROC) revealed 2 ng/ml and 10 ng/ml cut off serum PSA level for BPH and untreated carcinoma prostate patients (Ca−P). An extremely significant increase (P<0.0001) was observed in mean PSA concentration in BPH patients and adenocarcinoma prostate patients when compared to healthy males. Clinical relevance of PSA was highlighted by a case study of cancer patient prior to any therapy till death.     

我国各地区现代化进程研究

本文根据国际通行的现代化指标体系计算了中国大陆31个省市区的各项现代化指标的重分，采用主成分分析法和聚类分析法评估了各省市区的现代化水平及其分级和分类特征，并在此基础上分析了我国现代化水平的整体特点及地域分异特点。     

Analyzing imbalance among homogeneous index servers in a web search system

The performance of parallel query processing in a cluster of index servers is crucial for modern web search systems. In such a scenario, the response time basically depends on the execution time of the slowest server to generate a partial ranked answer. Previous approaches investigate performance issues in this context using simulation, analytical modeling, experimentation, or a combination of them. Nevertheless, these approaches simply assume balanced execution times among homogeneous servers (by uniformly distributing the document collection among them, for instance)—a scenario that we did not observe in our experimentation. On the contrary, we found that even with a balanced distribution of the document collection among index servers, correlations between the frequency of a term in the query log and the size of its corresponding inverted list lead to imbalances in query execution times at these same servers, because these correlations affect disk caching behavior. Further, the relative sizes of the main memory at each server (with regard to disk space usage) and the number of servers participating in the parallel query processing also affect imbalance of local query execution times. These are relevant findings that have not been reported before and that, we understand, are of interest to the research community.     

临床医学期刊在健康科普中的作用

随着泛在网络时代的到来,新媒体已成为人们获取健康知识的首要途径;但当前网络健康知识来源芜杂,各种夸大甚至歪曲医学事实的报道层出不穷,健康科普的“含金量”亟须提高。临床医学期刊是权威医学成果发布和交流的重要平台,拥有由作者、审者和编者等众多优秀医学专业工作者组成的专家团队,具有天然的健康科普优势和媒体属性。《协和医学杂志》通过将医学论文科普化、捕捉新闻热点、培养科普人才、充分利用新媒体平台等途径,证明临床医学期刊有责任更有能力在健康科普中发挥重要作用。     

Getting sloshed in outer space

We document some basic facts about how liquids behave in the low gravity of outer space and how this poses challenges to space scientists and engineers who need to design and test systems that handle fluids in outer space while working in the 1-g environment on Earth. N Ananthkrishnan is Director, Coral Digital Technologies (P) Ltd, a Bangalore-based company working in the area of multidisciplinary simulation and system integration of aerospace, naval and surface vehicles, and in the design and development of autonomous unmanned/micro air vehicles.