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排序方式: 共有486条查询结果,搜索用时 78 毫秒
81.
Walid E. Zahran Kholoud A. Salah El-Dien Philip G. Kamel Ahmed Shawky El-Sawaby 《Indian journal of clinical biochemistry : IJCB》2013,28(2):141-146
Tumor necrosis factor (TNF-α) is a cytokine involved in systemic inflammation during acute phase reactions. The current study was designed to investigate the levels of pro-inflammatory cytokine (TNF-α) along with the anti-inflammatory cytokine (IL-10) during progression of non-alcoholic fatty liver disease (NAFLD) from simple steatosis to non-alcoholic steatohepatitis (NASH) and fibrosis in diabetic patients, and correlate the levels of cytokines with the progression of NAFLD. Fifty-two diabetic patients compared to 18 healthy controls were participated in this study. Based on clinical diagnosis, patients were divided into three groups: simple steatosis, NASH and fibrosis. Serum liver function tests, fasting blood glucose, bilirubin, ALT, AST, TNF-α, IL-10 and lipid profile were measured. TNF-α levels were significantly higher in NAFLD patients compared to control subjects with a significant positive correlation with body mass index and fasting blood glucose (FBG) but with negative correlation with IL-10. Serum IL-10 levels were significantly lower in NAFLD patients compared with controls. A positive correlation between IL-10 and HDL-C with concomitant negative correlation between IL-10 and FBG and triacylglycerides was found. Cytokine analyses showed that there was a prominent imbalance between TNF-α and IL-10 in patients with NAFLD, and this imbalance increase by increasing the progression of NAFLD especially in obese diabetic patients. TNF-α and IL-10 could be used in diagnosis and follow-up of NAFLD stages in a way to avoid liver biopsies in greater proportion of patients. 相似文献
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Sohaib Ahmed Sameena Javaid Moazzam Fareed Niazi Anzar Alam Adnan Ahmad Murad Ali Baig 《Technology, Pedagogy and Education》2019,28(1):53-71
The use of Bluetooth Low Energy (BLE) beacons is becoming widespread for context-aware learning environments. This technology can be used in indoor and outdoor settings such as museums, shops, home and schools in order to identify the location of learners and their contexts. Specifically, in the constructivist view of learning, learners can use such sensing technology for constructing knowledge and experiencing learning at any time, anywhere. However, exploration of such technology has been limited in the constructivist context-aware ubiquitous learning (U-learning) literature. For this purpose, the authors evaluated two android-based U-learning applications: one was an outdoor learning environment in a garden, the other was about locating books in a library. The applications were implemented and tested with school and university students. The qualitative results are presented in this article, and show how such sensing technology is promising for both pedagogical environments. 相似文献
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Ines Ben Chobba Amine Elleuch Imen Ayadi Lamia Khannous Ahmed Namsi Frederique Cerqueira Noureddine Drira Néji Gharsallah Tatiana Vallaeys 《Journal of Zhejiang University. Science. B》2013,14(12):1084-1099
Endophytic flora plays a vital role in the colonization and survival of host plants, especially in harsh environments, such as arid regions. This flora may, however, contain pathogenic species responsible for various troublesome host diseases. The present study is aimed at investigating the diversity of both cultivable and non-cultivable endophytic fungal floras in the internal tissues (roots and leaves) of Tunisian date palm trees (Phoenix dactylifera). Accordingly, 13 isolates from both root and leaf samples, exhibiting distinct colony morphology, were selected from potato dextrose agar (PDA) medium and identified by a sequence match search wherein their 18S–28S internal transcribed spacer (ITS) sequences were compared to those available in public databases. These findings revealed that the cultivable root and leaf isolates fell into two groups, namely Nectriaceae and Pleosporaceae. Additionally, total DNA from palm roots and leaves was further extracted and ITS fragments were amplified. Restriction fragment length polymorphism (RFLP) analysis of the ITS from 200 fungal clones (leaves: 100; roots: 100) using HaeIII restriction enzyme revealed 13 distinct patterns that were further sequenced and led to the identification of Alternaria, Cladosporium, Davidiella (Cladosporium teleomorph), Pythium, Curvularia, and uncharacterized fungal endophytes. Both approaches confirmed that while the roots were predominantly colonized by Fusaria (members of the Nectriaceae family), the leaves were essentially colonized by Alternaria (members of the Pleosporaceae family). Overall, the findings of the present study constitute, to the authors’ knowledge, the first extensive report on the diversity of endophytic fungal flora associated with date palm trees (P. dactylifera). 相似文献
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Mohamed Taher Amin Ahmed Khan Muhammed Burhanuddin 《International Information and Library Review》2013,45(4):337-345
This paper relates to the difficulty in retrieving precise information from big repositories of magazine articles in full text, and proposes an Extended Markup Language (XML) vocabulary for improving retrieval rates. The hypothesis tested was as follows: Magazine articles marked up with an XML vocabulary, indexed only by selected parts, give more precise search results than the same search using full text index.The study was exploratory with the following characteristics: 29 magazine articles were tested for results, 8 scholars were interviewed for defining 23 search strategies and evaluating results. The data showed that precision improved from 40.72% with full text search to 62.84% using XML markup and searching only in specific labels.Revision of the vocabulary and more testing has to be done by the library and information science community in order to obtain a valid vocabulary and provide more research results. Cultural characteristics and politics of librarians and information managers’ community are as important as technical issues in order to consider any technical proposal to be implemented successfully to achieve interoperability. 相似文献
89.
Extensive use of social networking sites by students and teachers makes educators and researchers to think whether they can be incorporated in instructional process to facilitate students’ learning. This survey-based study records and examines Pakistani pre-service teachers’ and teacher-educators’ current uses of Facebook, and their attitudes toward using Facebook for collaborative learning, and to see if there is a significant relationship between participants’ intensity of Facebook use and their attitude toward instructional use of Facebook. Results of the study indicated that pre-service teachers’ and teacher-educators’ motives for their current Facebook use are mainly limited for social purposes. Pre-service teachers’ use of Facebook is more intensified than the use of Facebook by teacher-educators. Further, pre-service teachers showed more positive attitudes toward using Facebook for collaborative learning than the attitudes of their faculty. Findings also indicated a positive relationship between participants’ Facebook intensity and their attitudes toward its use for collaborative learning. 相似文献
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Five ratios RH, RT, SH, ST and SZ derived from the three-part division of a set of sources in h-core, h-tail and uncited sources are defined. Dynamic changes in the three independent ratios RH, SH and SZ are studied for six selected topics. Data about these topics are obtained from the Web of Science for scientific papers and Derwent Innovations Index for technical patents. It is observed that all RH- and SH-values decrease when the time span widens, while SZ stays the same or increases; and that all RH- and SH-values for papers are larger than the corresponding values for patents. The shifted Lotka distribution is used in a theoretical interpretation of these empirical phenomena. 相似文献