FLOSSWorld全球调查结果显示服务器更多使用开源软件

FLOSSWorld调查的主体由5部分构成,包括:个人(Private sector)、政府(Government sector)、开源社区参与者(Open Source participants community)、高校管理者(Heigher Education Institutes——Administrators)、高校信息部门主管(Heigher Education Institute——ITManagers)     

Synthetic and biological studies on a cyclopolypeptide of plant origin

Objective: A natural cyclic peptide previously isolated from Citrus medica was synthesized by coupling oftetrapep-tide units Boc-Leu-Pro-Trp-Leu-Ome and Boc-Ile-Ala-Ala-Gly-Ome after proper deprotection at carboxyl and amino terminals followed by cyclization of linear octapeptide segment.Methods: Solution phase technique was adopted for the synthesis of cyclooctapeptide--sarcodactylamide.Required tetrapeptide units were prepared by coupling of Boc-protected dipeptides viz.Boc-Leu-Pro-OH and Boc-Ile-Ala-OH with respective dipeptide methyl esters Trp-Leu-Ome and Ala-Gly-Ome.Cyclization of linear octapeptide unit was done by p-nitrophenyl ester method.The structure of synthesized cyclopolypeptide was elucidated by FTIR,1H NMR,13C NMR,FABMS spectral data and elemental analysis.The newly synthesized peptide was evaluated for dif-ferent pharmacological activities including antimicrobial,anthelmintic and cytotoxic activities.Results: Synthesis of sarcodac-tylamide was accomplished with >78% yield utilizing dicyclohexylcarbodiimide (DCC) as coupling agent.Newly synthesized peptide possessed potent cytotoxic activity against Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines,in addition to moderate anthelmintic activity against earthworms Megascoplex konkanensis,Pontoscotex corethruses and Eudrilus sp.Moreover,cyclopolypeptide displayed good antimicrobial activity against pathogenic fungi Candida albicans and Gram-negative bacteria Pseudomonas aeruginosa,in comparison to standard drugs griseofulvin and ciprofloxacin.Conclusion: Solution phase technique employing DCC and triethylamine (TEA) as base proved to be effective for the synthesis of natural cyclooctapeptide.N-methyl morpholine (NMM) was found to be a better base for the cyclization of linear octapeptide unit in comparison to TEA and pyridine.     

关于猫、黄金、老头和金字塔的三个不同故事

两位考古专家一同前去参观金字塔,晚上便住在开罗市郊的一家小旅馆里,一个人留在房间里面写工作日记,另一个人就上街闲逛。他在路边发现有一个老妇人在卖一只黑色的工艺猫,要价1000元。他忽然发现这只猫的两只眼睛竟是两颗大     

职业教育基本问题访谈录(I) 职业教育是什么

全国教育科学“十五”规划国家一般课题《职业教育几个基本问题研究》(BJA010100)课题组就“职业教育的基本问题”对国内外职业教育界的专家、学者进行了访谈,使我们看到了对此问题的不同角度和层面的理解。这是一次思想的碰撞,有利于我们深化对职业教育基本问题的认识。本刊特将访谈记录分专题编辑处理,并从本期起连续刊发,本期论题为“职业教育是什么?”     

生物学教科书中的错误和概念不正确：细胞生理学

本文是关于教科书中的错误和概念不正确以及过时提法的系列文章中的第五篇,供中学和大学普通生物学课程教师阅读。第一篇是关于光合作用的、第二篇关于细胞结构、第三篇关于细胞的新陈代谢、第四篇关于细胞能力学。写作这一系列文章的目的以前曾作过说明。本文讨论教科书中有关细胞功能方面常被误解、或被忽略的问题。     

基于国家教育标准的地理教材

为进一步增强美国地理教育。我们要做的许多事情之一就是改进教材的质量。其中最主要的三个方面的任务是:(1)开发优良的教材,(2)利用教师联盟的在职培训网络和职前教育计划培训教师使用这种新教材,(3)通过提供强有力的课程指导,特别是将教材与师资培训和基于国家     

心路历程--流逝的岁月

Old age gives us the privilege to explore, to innovate, to challenge.Dear Friends,This is our twelfth monthly column and the first-year anniversary of our conversation together in the pages of Overseas English. We call this a milestone in English. Is there a Chinese word for it?I would like to begin our column with one of my own poems.     

为大学毕业生开设的速成本科护理课程与传统护理课程学生成绩的比较

由于技术进步,经济波动,护理短缺,护理患者所需知识的增加,人们对新的护理教育模式更感兴趣。目前美国各地许多护理院校已采取了各种不同模式的学士后护理教育,大致有三种新的模式:对非护理学院毕业生的护理学士学位课程,普通硕土学位课程和护理博士学位课程。作者对新旧两种护理学士学位课程的学生进行了比较,发现新模式培养的学生在护理成绩和注册护士考试通过率方面明显高于传统模式教育的学生。