Oxidative stress and antioxidant status in cervical cancer patients

Cervical cancer (CaCx) is a global public health problem as it is the second most common cancer leading to the death of women worldwide. Many references revealed that the low levels of antioxidants induce the generation of free radicals leading to DNA damage and further mutations. In the present study attempt have been made to evaluate the levels of serum Lipid peroxide, Nitric Oxide (NO^.) Erythrocytic—Superoxide Dismutase (RBC-SOD), Vitamin-C, serum Copper (Cu) and serum Zinc (Zn). 120 patients were divided in 4 groups according to the increasing CaCx stages i.e. stage I, II, III & IV respectively. All the patients were around the age group of 25–65 years. 30 healthy women between the same age group were treated as controls. Highly significant increased values of MDA, NO^. and Cu were observed (p<0.001) whereas the activity of RBC-SOD, levels of Vitamin-C and Zn were significantly decreased in CaCx patients as compared with healthy controls (p<0.001). Cu/Zn ratio was found to be altered in CaCx patients. From our findings it can be concluded that the oxidative stress is induced among CaCx patients, which inturn increases the risk of CaCx.     

Motivation for and Extent of Participation in Organized Sports by High School Seniors

Abstract

The purpose of this study was twofold: (a) to replicate previous studies in which selected demographic and socioeconomic factors were examined as influences on socialization into youth sport and (b) to extend previous research by analyzing the effects of parental influence on involvement in and motivations toward sport. The range of focus in this study was from the time of the subjects' first encounter with organized sport through the senior year of high school. Data were obtained from direct administration of the questionnaire to twelfth-grade students in four Jackson, Mississippi, high schools. Regression analysis revealed that significant independent variables accounted for nearly 26% of the variance in sport involvement in one setting and nearly 10% of the variance in motivations toward involvement in sport and recreational activities. Subjects' gender, their fathers' past athletic experiences, and mothers' educational levels were the most influential independent variables. Influences varied between school sports and out-of-school sports and over the sports career of subjects.     

One‐year teaching internships and the dimensions of beginning teacher development

The authors draw on data from weekly e‐mail responses to a questionnaire completed by beginning teachers placed in one‐year, paid, internships. Interns were assigned mentors who responded every several weeks, also via e‐mail, to a questionnaire about the interns and their development. Data from 23 interns were analyzed. Seven themes were identified that capture various dimensions of intern development. To portray the nature, direction and complexity of intern development, each of the dimensions is conceptualized in terms of opposable orientations to the defining aspect of each theme. The authors use the dimensions and their related orientations to organize the data for discussion. Conclusions related to each dimension are situated within the wider research literature on teacher development, and some similarities and differences are noted between this group of interns and what is widely reported about beginning teacher development.

One‐year teaching internships and the dimensions of beginning teacher development

All authors

Robert V. Bullough, Jr * , Janet Young & Roni Jo Draper

https://doi.org/10.1080/1354060042000224124

Published online:

04 August 2006

Table     

Focus: between and beyond "histories of science" and "histories of medicine". Introduction

Historians tend to treat science and medicine as having developed in parallel, and we maintain separate societies and journals, often giving primacy to science, at least for intellectual history. Yet much of "science" before circa 1800 was dependent on the organizations of medicine, and much of science now is promoted for the improvement of medical diagnoses and therapies. This Focus section unpicks some of the historical and historiographical relationships, recognizing the present prominence of biomedicine and the diminishing utility of distinctions between science, medicine, and technology.