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11.
Increasingly, research has focused on the cognitive processes associated with various standard-setting activities. This qualitative study involved an examination of 16 third-grade reading teachers' experiences with the cognitive task of conceptualizing an entire classroom of hypothetical target students when the single-passage bookmark method or the yes/no method was used during a one-day mock panel meeting. Data were collected using in-depth focus group interviews with eight participants from each of the panel meetings, and a whole-text analysis revealed three categories. Most participants experienced difficulty in attempting to conceive of an entire classroom of target students. Most of them were ultimately unable to do so and made use of alternative cognitive strategies. More fundamental issues also contributed to the difficulties experienced in attempting to complete the required cognitive task. Implications of the findings for standard setting and for further research are also discussed.  相似文献   
12.
The aim was to develop, implement, and evaluate a physical education-based coping training program for vocational students. Two vocational schools participated in the quasi-experimental pilot study (EPHECT I). One school received the intervention (intervention group: n?=?434), while the other school maintained regular physical education classes (control group: n?=?430). Repeated measures ANCOVAs were used to examine the effects on coping and perceived stress. Additionally, effects were compared among students who reported low versus elevated life satisfaction. Finally, the implementation rate was considered as a moderating factor. Overall, no significant time by group effects were found between the intervention group and the control group. However, a reduction in maladaptive coping occurred among students of the intervention group who reported low life satisfaction. The implementation rate did not moderate the findings. Despite a relatively low implementation rate, the intervention program reduced maladaptive coping strategies in adolescents with low life satisfaction. Program monitoring needs to be increased in future research.  相似文献   
13.
Oxidative stress is thought to be involved in the pathophysiology of malaria, especially in pregnancy where natural resistance is markedly reduced. In the present study we investigated oxidative stress in 315 pregnant women out of which 159 had Plasmodium falciparum malaria and 154 controls. We evaluated the level of lipid peroxidation products (MDA level) in the plasma, the activity of erythrocyte antioxidant defense enzymes, superoxide dismutase (SOD, EC: 1.15.1.1) and catalase (Cat, EC: 1.11.1.6) as well as the ability to resist oxidative stress by the FRAP (Ferric Reducing Ability of Plasma) assay. Total erythrocyte protein levels were also examined. For the two groups of patients, several differences between the biochemical parameters tested were found. Median parasitaemia in women with malaria was 25,392 parasites/μl of blood (Range1200–82000), while in controls we had no parasites found in thin and thick smears. Levels of lipid peroxidation products (MDA) were significantly higher in patients with parasitemia than in healthy asymptomatic volunteers (mean: 0.844 ± 0.290 and 0.384 ± 0.129 respectively, p<0.001). This MDA level was higher in primigravidea and also correlates well with parasite density (p<0.001). Catalase activity in erythrocytes of women with malaria did not differ statistically from that of controls. In contrast, SOD activity of patients with malaria was found to be significantly higher than that of controls (mean: 0.7899 ± 0.2777 and 0.4263 ± 0.2629 respectively, p<0.05). FRAP values declined, from parasitemic patients (1.4619 ± 0.6565) compare to controls (2.4396 ± 0.8883, p<0.05), particularly in the first and third trimester of gestation (p<0.05 and p<0.01 respectively). Finally, total erythrocyte protein concentrations of women with malaria did not differ from that of the controls. Our results suggest an imbalance between oxidants and antioxidants in pregnant women suffering from malaria, a situation which could lead to severe damage for either the mother or the fetus. Therefore, further research should be done to assess the potential benefits of antioxidant supplementation for the pregnant women suffering from malaria.  相似文献   
14.
Background: Although most adolescents successfully manage the transition between childhood and adulthood, the speed and magnitude of these changes may exceed the coping abilities of a significant number of young people. For vocational students, additional responsibilities arise during the vocational school transition and the need to balance academic and job-related requirements. An expanding body of literature suggests that adolescence is a vulnerable period for the development of psychiatric diseases and as such, the need to develop an adequate coping repertoire is receiving increasing attention globally. The growing awareness of long-term consequences of stress has led governments to instill school-based resilience promotion programs. For instance, the new physical education (PE) curriculum of vocational (vocational education and training (VET)) students in Switzerland addresses stress management, because stress-related diseases at the workplace have become commonplace among young professionals.

Purpose: Our aim was to develop, implement and evaluate a PE-based coping training (EPHECT) for VET students. Therefore, we adapted components of extant field-tested coping training programs and tailored them to the unique needs of VET students. To facilitate the standardization of the program, each teacher received a teaching manual. Moreover, drawing upon experiential learning theory, we introduced the contents of the coping training in PE class through practical, movement-based exercises in PE. Students also received a workbook for use at home.

Participants and research design: In this cluster randomized controlled trial, eight classes from a Swiss vocational school participated (N?=?131, Mage?=?16.22?±?1.12, 35% females). Two trained PE teachers implemented the program with students in the intervention group (IG?=?67) for three months, while students in the other four classes maintained regular PE (CG?=?64) to comprise the control group. To evaluate the coping training, all participants completed several self-report psychological questionnaires (assessing stress, coping and sleep) at baseline and follow-up. IG students completed further questions with regard to intervention fidelity at follow-up.

Data analysis: To evaluate possible effects of the coping training on stress, coping and sleep, a 2?×?2 repeated-measures analysis of variance design was executed with time (pre vs. post) and group (IG vs. CG) as within- and between-subject factors.

Findings: Over time, IG students significantly increased their adaptive coping compared to CG students, while stress and sleep remained relatively stable for both. Regularly completing one’s homework reinforced this effect because it was significantly associated with students’ reflection and compliance.

Conclusion: A complete and accurate implementation of a PE-based coping training can make a positive contribution to the development of adaptive coping skills among adolescents attending vocational schools. This PE-based program allows students to experience their responses to stress directly and offers opportunities to experiment with different coping strategies. Adaptive coping skills are vital for successful stress management and the prevention of stress-related disorders across the work domain and in everyday life.  相似文献   
15.
The aim of this study was to determine the effects of frequency of verbal encouragement during maximal exercise testing. Twenty-eight participants (12 males, 16 females) aged 20.9 +/- 1.5 years (mean +/- s) performed a maximal exercise test (VO2max) on a treadmill without any verbal encouragement. The participants were matched according to their pre-test VO2max and placed into either a control group or one of three experimental groups. They performed a second exercise test (post-test) 1 week later. During the second test, the control group received no verbal encouragement; the 20 s (20E), 60 s (60E) and 180 s (180E) encouragement groups received verbal encouragement every 20, 60 and 180 s, respectively, beginning with stage 3 of the exercise test. Relative VO2max, exercise time, blood lactate concentration, respiratory exchange ratio (RER) and ratings of perceived exertion (RPE) were not significantly different from the first test to the second test for the control group without verbal encouragement and the 180E group that received infrequent encouragement. Post-test values were significantly higher than pre-test values for the 20E and 60E groups. The post-test values of the 20E group were significantly higher than their pre-test values for relative VO2max (P < 0.001), exercise time (P < 0.0001), blood lactate concentration (P < 0.05), RER (P < 0.01) and RPE (P < 0.0001); this was also the case for the 60E group for relative VO2max (P < 0.01), blood lactate concentration (P < 0.05), RER (P < 0.05) and RPE (P < 0.05). The results suggest that frequent verbal encouragement (every 20 s and 60 s in the present study) leads to significantly greater maximum effort in a treadmill test than when no encouragement is given or when the encouragement is infrequent (i.e. every 180 s).  相似文献   
16.
In this study, we examined the effects of three recovery intensities on time spent at a high percentage of maximal oxygen uptake (t90[Vdot]O(2max)) during a short intermittent session. Eight endurance-trained male adolescents (16 +/- 1 years) performed four field tests until exhaustion: a graded test to determine maximal oxygen uptake ([Vdot]O(2max); 57.4 +/- 6.1 ml x min(-1) . kg(-1)) and maximal aerobic velocity (17.9 +/- 0.4 km x h(-1)), and three intermittent exercises consisting of repeat 30-s runs at 105% of maximal aerobic velocity alternating with 30 s active recovery at 50% (IE(50)), 67% (IE(67)), and 84% (IE(84)) of maximal aerobic velocity. In absolute values, mean t90[Vdot]O(2max) was not significantly different between IE(50) and IE(67), but both values were significantly longer compared with IE(84). When expressed in relative values (as a percentage of time to exhaustion), mean t90[Vdot]O(2max) was significantly higher during IE(67) than during IE(50). Our results show that both 50% and 67% of maximal aerobic velocity of active recovery induced extensive solicitation of the cardiorespiratory system. Our results suggest that the choice of recovery intensity depends on the exercise objective.  相似文献   
17.
18.
In this study, we developed a miniaturized microfluidic-based high-throughput cell toxicity assay to create an in vitro model of Parkinson's disease (PD). In particular, we generated concentration gradients of 6-hydroxydopamine (6-OHDA) to trigger a process of neuronal apoptosis in pheochromocytoma PC12 neuronal cell line. PC12 cells were cultured in a microfluidic channel, and a concentration gradient of 6-OHDA was generated in the channel by using a back and forth movement of the fluid flow. Cellular apoptosis was then analyzed along the channel. The results indicate that at low concentrations of 6-OHDA along the gradient (i.e., approximately less than 260 μM), the neuronal death in the channel was mainly induced by apoptosis, while at higher concentrations, 6-OHDA induced neuronal death mainly through necrosis. Thus, this concentration appears to be useful for creating an in vitro model of PD by inducing the highest level of apoptosis in PC12 cells. As microfluidic systems are advantageous in a range of properties such as throughput and lower use of reagents, they may provide a useful approach for generating in vitro models of disease for drug discovery applications.  相似文献   
19.
Book reviews     
Serge Wagner 《Prospects》1984,14(3):429-431
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20.
ABSTRACT

There are well-known biological differences between women and men, especially in technical-coordinative variations that contribute to sex differences in performance of complex movements like the most important offensive action in volleyball, the spike jump. The aim of this study was to investigate sex-dependent performance and biomechanical characteristics in the volleyball spike jump. Thirty female and male sub-elite volleyball players were analysed while striking a stationary ball with maximal spike jump height. Twelve MX13 Vicon cameras with a cluster marker set, two AMTI force plates, surface EMG, and a Full-Body 3D model in Visual3D were used. Main findings include sex differences (P< .05) in jump height (pη2 = .73), approach [speed (pη2 = .61), step length], transition strategy [plant angle, neuromuscular activation (pη2 = .91), horizontal force maxima and impulses], acceleration distances [centre of mass displacement (pη2 = .21), minimal knee and hip angles], use of torso and arms [incline, angular velocity (pη2 = .23)]. Correlations support that the results cannot be explained fully by strength and power differences between sexes but represent the product of technical-coordinative variations. Their relevance is acknowledged for both sexes and numerous performance determinants displayed sex differences. The integration of such attributes into sex-specific training seems promising but its effect requires further investigation.  相似文献   
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