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141.
Sonika Raj Vijay Lakshmi Sharma Amarjeet Singh Sonu Goel 《Health information and libraries journal》2015,32(2):143-149
This article represents two‐firsts for the feature – it is the first to report on a study outside the UK and the first to examine the health information needs of community health workers. Sonika Raj is pursuing PhD at the Centre for Public Health, Panjab University, Chandigarh, in India and she conducted her research in Chandigarh. The article outlines the important role that health workers at community level play in determining health outcomes in the developing world, including Chandigarh. It demonstrates that while those workers recognise their information needs, there are many issues affecting their ability to access health information effectively, not least their limited access to appropriate technology and training. AM 相似文献
142.
An assemblage of Buddhist wall paintings and sculptures dating to the twelfth/early thirteenth century are found distributed over the interiors of the temple complex at Sumda Chun, Ladakh. Detailed investigations carried out as part of a conservation project shed light on their antiquity and production technology. The sculptures are constructed with fine mud mortar applied over a wooden armature and affixed to the walls without any support from the ground. In both the sculptures and wall paintings, the paint layer is applied over a thin gypsum ground that functions as a white colourant where unpainted. For the paint layer, azurite, vermilion, and orpiment are the dominant mineral pigments utilized. Minium (red lead) has been used for preparatory drawings and as paint. Highlighting of special areas was achieved using a laminate of tin–lead alloy and gold on relief. Overall the material and techniques employed in the execution of the wall paintings and sculptures are consistent with those reported for other early sites in the region. 相似文献
143.
Jyoti Aggarwal Akansha Singh Sanjeev Gupta Rajendra Prasad 《Indian journal of clinical biochemistry : IJCB》2021,36(1):120
Psoriasis is a common and an inflammatory skin disease. Trace elements play an important role in the skin metabolism such as keratinisation and melanin formation as well as immunological and inflammatory reactions. Henceforth, the present study was aimed to evaluate the essential metals with special reference to Cu and Zn. In this study, 72 psoriatic patients and 50 controls were enrolled. On the basis of PASI score psoriatic group comprising of 48 mild and 24 severe psoriatic patients were grouped. The serum trace elements analysis in the subjects revealed that serum Cu levels and Cu/Zn ratio was significantly higher in the psoriatic patients as compared to controls. Interestingly, severity of the psoriasis was well correlated with the serum Cu levels. Taking together, all these findings suggest that Cu may be a major culprit in the pathogenesis as well as in the severity of the disease. 相似文献
144.
Nidhi Gupta Ramesh Kandimalla Kumari Priyanka Gagandip Singh Kiran Dip Gill Surjit Singh 《Indian journal of clinical biochemistry : IJCB》2014,29(1):69-73
Dietary and lifestyle factors have been shown to have a profound effect on paraoxonase-1 (PON1) activity. Cigarette smoke has been shown to inhibit its mass and activity where as resveratrol has been shown to enhance it. We exposed hepatoma derived cell line (HepG2) to resveratrol and nicotine in varying doses and measured PON1 enzymatic activity and PON1 gene expression. In addition, total protein content of HepG2 cells was also measured. Resveratrol in a dose of 15 μmol/l or above significantly increased the PON1 enzyme activity (p > 0.001) where as nicotine in a dose of 1 μmol/l or higher significantly reduced it (p < 0.05). The resveratrol in this dose also enhanced the PON1 gene expression whereas nicotine decreased it as compared to controls. However, the protein conent of cells was not changed suggesting that they were not cytotoxic in the doses used. Till date the antioxidant vitamins have shown disappointing results against LDL oxidation and cardiovascular protection. However, the effect of resveratrol on PON1 gene expression and activity was significant, suggesting increase in PON1 activity and enhanced gene expression may be its alternative mechanism for offering protection against cardiovascular disease and may be an potential pharmacological agent which can be used for this. 相似文献
145.
Ravjit Kaur Sabharwal Parduman Singh M. M. Arora B. L. Somani Vivek Ambade 《Indian journal of clinical biochemistry : IJCB》2008,23(1):71-75
The prevalence of microalbuminuria was assessed in 174 albustix negative hypertensive patients by estimating albumin in the
morning random urine samples by immunoturbidimetric method within four hours of voiding of urine. The urine samples were not
stored and collected without any preservatives. The urinary albumin was calculated in terms of ratio with respect to urinary
creatinine and expressed as albumin creatinine ratio (mg/g). Out of 174 albustix negative hypertensives, 58 (33.3%) patients
were found to have microalbuminuria. The prevalence of microalbuminuria in males and females was found to be 34% and 30.7%
respectively. No correlation was found between the Body Mass Index (BMI) and albumin excretion (r2 = 0.0271) and between duration of hypertension and urinary albumin excretion (r2 = 0.0042). Prevalence of microalbuminuria in nonsmokers and non-alcoholic hypertensives was 20%. The prevalence in alcoholics,
smokers and both smokers and alcoholics was found to be 35%, 42% and 41% respectively. The high prevalence of microalbuminuria
than the various reported studies on the subject demands establishment of a screening programme for microalbuminuria, implementation
of specific intervention methods and education of hypertensive patients about the consequences of smoking and alcohol on possible
involvement of renal system. 相似文献
146.
147.
Pradeep Sharma Neelima Singh Vinod Singh Sanjeev Singh Harsh vardhan Singh Sameer Gupta 《Indian journal of clinical biochemistry : IJCB》2006,21(1):205-207
Osteoarthritis of knee joints is a disease of old age in both sex. It is very common after the age of 40 years in elderly
females or in postmenopausal phase of females. It is characterized by narrowing of space in joints due to inflammation. The
exact mechanism of inflammation in this disease is not yet clear. Tumor necrosis factor alpha (TNF-α) may involve in onset
of disease. The present study is being carried out in 130 female subject of age group 40–60 years suffering from osteoarthritis
of knee joints and 50 normal healthy control female subjects. A correlation is made between TNF-α and estrogen and found significant
inverse correlation (r<0.001), between TNF-α and estrogen hormone in osteoarthritic female patients as compared to normal
healthy control female group. 相似文献
148.
Jasvir Kaur Nachatar Singh 《Higher Education Quarterly》2023,77(3):501-514
Limited scholarly work has been conducted on obtaining equal opportunities to participate in employability-related programmes by international students while studying in Australia. Drawing on a qualitative study, 20 South Asian postgraduates were interviewed to explore their experiences in accessing employability-related programmes. Based on the findings, South Asian graduates have experienced unequal opportunities in accessing employability-related programmes as postgraduate international students in Australia. They are disadvantaged by generic career advice and resume assistance offered by their university career office, and companies invited to university career fairs offer internships, placements or graduate programme opportunities mostly to domestic students. As a result, South Asian graduates were unable to gain employment in their field of studies. South Asian graduates have also offered several useful recommendations to facilitate more equal chances of developing employability and thereby gaining successful employment in Australia. These include partnerships with companies in providing employment opportunities, diversification of university career office roles, and establishing connections with alumni. The paper also discusses implications for Australian higher education institutions and higher education policy and practice in Australia. 相似文献
149.
Arindama Singh 《Resonance》2017,22(12):1205-1211
We present a ball game that can be continued as long as we wish. It looks as though the game would never end. But by applying a result on trees, we show that the game nonetheless ends in some finite number of moves. We then point out some deep results on the natural number system connected with the game. 相似文献
150.
Sutirtha Chakraborty Anindya Dasgupta Harendra Nath Das Om Prakash Singh Asok Kumar Mandal Nikhiles Mandal 《Indian journal of clinical biochemistry : IJCB》2009,24(2):194-197
Oxidative stress has been found to play important role in several neuropsychiatric diseases including Obsessive Compulsive
Disorder. A longitudinal case control study was conducted to evaluate the oxidative stress in 30 newly diagnosed obsessive
compulsive disorder patients and same number of control patients. Serum thiobarbituric acid reacting substances, plasma ascorbate
were assessed to evaluate oxidative stress and Yale Brown obsessive compulsive scale for disease severity before and after
treatment with Fluoxetine at the average dosage of 40 mg/day. Improvement in Yale Brown obsessive compulsive scale score by
about 43% after 12 weeks treatment was associated with significantly decreased thiobarbituric acid reacting substances and
increased plasma ascorbate values (p < 0.05). The newly diagnosed obsessive compulsive disorder patients had higher serum
thiobarbituric acid reacting substances as well as a lower plasma ascorbate levels than the control population. Thus, the
present study suggested a significant role of oxidative stress in obsessive compulsive disorder and showed that a successful
treatment with Fluoxetine not only improves the clinical scenario but also reduces the oxidative stress that may further improve
the prognosis of the disease. 相似文献