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231.
232.
Rachna Agarwal Suman S. Kushwaha C. B. Tripathi Neeraj Singh Neelam Chhillar 《Indian journal of clinical biochemistry : IJCB》2008,23(4):369-374
Alzheimer’s disease is the most common form of dementia in the elderly and it’s prevalence is rapidly rising. Oxidative stress
plays important role in the pathophysiology of Alzheimer’s disease. Metals like copper, iron derived through diet can act
as pro-oxidant under oxidative stress. In the present study, serum copper levels were evaluated in 50 patients with Alzheimer’s
disease, 24 patients with Vascular Dementia and 30 controls. All the groups were also investigated for serum ceruloplsmin
levels. The mean copper levels in Alzheimer’s disease and Vascular Dementia were significantly raised compared to controls.
An attempt has been made to study the relationship of serum copper with ceruloplasmin. Our study found weak correlation between
copper and ceruloplasmin levels in Alzheimer’s disease and Vascular Dementia. 相似文献
233.
Amar B. Singh J. P. Chaturvedi T. Narender Arvind K. Srivastava 《Indian journal of clinical biochemistry : IJCB》2008,23(4):391-393
Peganum harmala L. (Zygophyllaceae) is a traditional medicine used for the treatment of variety of human ailments, including
antidepression, hallucination, antileishmaniasis etc. We report for first time the hypoglycemic activity of the ethanolic
extract of this plant at two dose levels of 150 and 250mg/kg bw in sucrose challenged normal as well as in rats with streptozotocin
induced diabetes. The oral administration of ethanolic extract causes maximum fall of blood glucose level to 22.9% (p<0.05)
and 29.4% (p<0.01) respectively with the two doses in normal and 30.3% (p<0.01) and 48.4% (p<0.001) in diabetic rats. The
standard drug metformin treated group showed 28.0% (p<0.01) and 45.5% (p<0.001) respectively in normal and diabetic rats.
The above results show that the ethanolic extract of P. harmala is as effective as metformin in reducing the blood glucose
levels of normoglycemic and streptozotocin-induced diabetic rats. 相似文献
234.
Zolianthanga Zongte L. Shaini Asis Debbarma Th Bhimo Singh S. Bilasini Devi W. Gyaneshwar Singh 《Indian journal of clinical biochemistry : IJCB》2008,23(2):154-157
Hyperhomocysteinemia has been considered an independent risk factor in the development of stroke. The present study was undertaken
to evaluate serum homocysteine levels in patients with cerebrovascular accidents among the Manipuri population and to compare
with the normal cases. Ninety-three cerebrovascular accident cases admitted in the hospital were enrolled for the study and
twenty-seven age and sex matched individuals free from cerebrovascular diseases were taken as control group. Serum homocysteine
levels were estimated by ELISA method using Axis homocysteine EIA kit manufactured by Ranbaxy Diagnostic Ltd. India. The finding
suggests that hyperhomocysteinemia is associated with cerebrovascular accident with male preponderance, which increases with
advancing age. However, whether hyperhomocysteinemia is the cause or the result of cerebrovascular accidents needs further
investigations. 相似文献
235.
236.
Malkeet Singh 《Educational Research and Evaluation》2013,19(1):4-18
Eliminating inequity in public education is a central goal of the No Child left Behind (NCLB) act. Controlling for 3rd-grade performance, the impact of English language learner (ELL) status, socioeconomic status (SES), and special education (SPED) status on a cohort’s reading performance was investigated from elementary to high school through a multilevel framework. Results in Hawaii show that the negative impact of low SES and SPED status persists up to high school, while the disadvantage of ELL status is restricted within the elementary grades. Moreover, individual characteristics, not school characteristics, have a dominant impact on future reading performance. Among individual characteristics, early performance is a crucial factor for future academic achievement. The findings show that educational policies that use incentives and sanctions such as NCLB to close achievement gaps may not be successful. 相似文献
237.
Satendra Singh 《Anatomical sciences education》2010,3(1):50-51
Peer‐assisted learning as de rigueur is reverberating in medical institutions around the world. Anatomy classroom activities are challenging and different, and the stressful environment of dissection rooms poses a greater challenge than what can be addressed through peer‐assisted learning. It is here that “near‐peer role modeling” is not only likely to be more useful, both to the students as well as their near‐peer teachers, but also holds the answer to the worsening faculty shortage in anatomy education. Anat Sci Educ 3:50–51, 2010. © 2010 American Association of Anatomists. 相似文献
238.
Sagar Dholariya Deepak Narayan Parchwani Ragini Singh Amit Sonagra Anita Motiani Digishaben Patel 《Indian journal of clinical biochemistry : IJCB》2021,36(4):451
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the etiological agent of coronavirus disease-2019 (COVID-19), is a highly contagious pathogenic coronavirus to emerge and spread in human populations. Although substantial exertions have been laid to avert spread of COVID-19 by therapeutic and preventive countermeasures, but emergence of SARS-CoV-2 variants as a result of mutations make the infection more ominous. New viral confers a higher nasopharyngeal viral load, increased viral transmissibility, higher infectiousness, immune escape, increased resistance to monoclonal/polyclonal antibodies from convalescence sera/vaccine, and an enhanced virulence. Thus, it is pertinent to monitor evolving mutations and genetic diversity of SARS-CoV-2 as it is decisive for understanding the viral variants. In this review we provide an overview of colloquial nomenclature and the genetic characteristics of different SARS-CoV-2 variants in the context of mutational changes of the circulating strains, transmissibility potential, virulence and infectivity. 相似文献
239.
Biosensors function by coupling a biological sensing element with a detector system using a transducer. They are widely used
in diagnostics, pharmaceutical research, fermentation-based industries and environmental and pollution monitoring. 相似文献
240.