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91.
Katja Uhlig Bj?rn Boysen Andreas Lankenau Magnus Jaeger Erik Wischerhoff Jean-Fran?ois Lutz André Laschewsky Claus Duschl 《Biomicrofluidics》2012,6(2)
Thermoresponsive polymer surface coatings are a promising tool for cell culture applications. They allow for a mild way of cell detachment that preserves the activity of membrane proteins—a prerequisite for reliable cell analysis. To enlarge the application range of these coatings to cells with different adhesion properties, we synthesized various novel poly(ethylene glycol)-based thermoresponsive polymers and describe how (i) their chemical structure and (ii) their surface density affect their efficiency. In order to quantify the influence of both factors, the time for cell spreading and rounding efficiency were observed. As a result, efficiency of cell rounding, which is closely correlated to cell detachment, is less affected by both factors than the time needed for cell spreading. This time can effectively be adjusted by the molecular architecture which includes the length of the polymer backbone and the side chains. Based on this work, recommendations are given for future optimization of functionality of thermoresponsive polymer coatings for cell culture applications. 相似文献
92.
Riikka Hirvonen George K. Georgiou Marja‐Kristiina Lerkkanen Kaisa Aunola Jari‐Erik Nurmi 《Journal of Research in Reading》2010,33(3):302-319
The purpose of this study was twofold: (a) to examine the effect of task‐focused behaviour on reading fluency, spelling and comprehension; and (b) to examine the role of the different literacy skills in subsequent task‐focused behaviour. Two hundred and seven Finnish‐speaking children were followed from preschool until their fourth year at school and were tested for reading fluency, spelling and reading comprehension. The teachers also rated the children's task‐focused behaviour. The results showed that task‐focused behaviour was a significant predictor of later reading comprehension and spelling skills. However, all three literacy skills predicted subsequent task‐focused behaviour. 相似文献
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94.
Exploiting Hierarchy in Text Categorization 总被引:4,自引:3,他引:1
With the recent dramatic increase in electronic access to documents, text categorization—the task of assigning topics to a given document—has moved to the center of the information sciences and knowledge management. This article uses the structure that is present in the semantic space of topics in order to improve performance in text categorization: according to their meaning, topics can be grouped together into meta-topics, e.g., gold, silver, and copper are all metals. The proposed architecture matches the hierarchical structure of the topic space, as opposed to a flat model that ignores the structure. It accommodates both single and multiple topic assignments for each document. Its probabilistic interpretation allows its predictions to be combined in a principled way with information from other sources. The first level of the architecture predicts the probabilities of the meta-topic groups. This allows the individual models for each topic on the second level to focus on finer discriminations within the group. Evaluating the performance of a two-level implementation on the Reuters-22173 testbed of newswire articles shows the most significant improvement for rare classes. 相似文献
95.
Henk Erik Meier Till Utesch Charlotte Raue Christina Uhlenbrock Nabila Chababi Bernd Strauss 《Sport in Society》2019,22(3):476-498
It is commonly assumed that sport plays an important role for national identity. However, empirical research has primarily focused on sport’s role for emotional-affectice rather than cognitive aspects of national identity. Therefore, research presented here explores whether identification with the German national soccer team serves to reinforce ethnic or civic conceptions of national identity. Analyses of a unique dataset conducted during the 2014 FIFA World Cup and the 2016?EURO show that national team identification is an important determinant of national pride and national belonging. Respondents who identify with the national soccer team can adhere to different conceptions of national identity. It seems that national pride and affection as well as conceptions of national identity represent stable attitudes not affected by the success of the national team. Further research should improve conceptual clarity and measurement. 相似文献
96.
Hans Erik Næss 《国际体育史杂志》2017,34(7-8):535-553
As the governing body of world motorsports since 1904, Fédération Internationale de l’Automobile (FIA) has, through the growth of Formula 1, become increasingly embedded in the globalization of commerce and faced with difficult political issues. Specifically, FIA events are used to sanitize the image of undemocratic countries, and FIA is, thus, becoming increasingly entangled in spheres other than sport. This presents a challenge to a sporting body which traditionally follows the principle of not mixing sport and politics. To explore this topic, two Formula 1 races where sport and politics are intertwined are chosen as examples: the 1985 South African Grand Prix and the 2016 Azerbaijan Grand Prix. As the holding of both events evoked controversy, for various reasons, this paper investigates whether something has changed at FIA along the way, and, in that case, what? As findings demonstrate, while the races differ and the context has changed, the FIA has kept its policy despite the fact that it has become increasingly difficult to maintain its neutral stance. 相似文献
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99.
Swedish higher education institutions havebeen given increased autonomy to organise theirinternal affairs, raising numerous demands onleadership and governance. Changes are so profoundthat institutions wanting to create an`entrepreneurial response' through a newdecision-making structure must undergo a culturerevolution, threatening existing power structures. Three organising principles are used to describe andanalyse Göteborg University. One conclusion isthat collegial decision-making bodies shouldsimultaneously be redefined, reestablished andabolished, depending on the issues dealt with.Commissions as deans and department heads must beclear and accountable to superiors or tonon-sub-optimising boards in a balanced powerstructure. 相似文献
100.