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521.
This paper examines international standard-setting in the toxicology of pharmaceuticals during the 1990s, which has involved both the pharmaceutical industry and regulatory agencies in an organization known as the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). The analysis shows that the relationships between innovation, regulatory science and 'progress' may be more complex and controversial than is often assumed. An assessment of the ICH's claims about the implications of 'technical' harmonization of drug-testing standards for the maintenance of drug safety, via toxicological testing, and the delivery of therapeutic progress, via innovation, is presented. By demonstrating that there is not a technoscientific validity for these claims, it is argued that, within the ICH, a discourse of technological innovation and scientific progress has been used by regulatory agencies and prominent parts of the transnational pharmaceutical industry to legitimize the lowering and loosening of toxicological standards for drug testing. The mobilization and acceptance of this discourse are shown to be pivotal to the ICH's transformation of reductions in safety standards, which are apparently against the interests of patients and public health, into supposed therapeutic benefits derived from promises of greater access to more innovative drug products. The evidence suggests that it is highly implausible that these reductions in the standards of regulatory toxicology are consistent with therapeutic progress for patients, and highlights a worrying aspect embedded in the 'technical trajectories' of regulatory science. 相似文献
522.
Instructional Science - In research on learning with animations compared to static pictures usually very short and narrowly defined topics are chosen. However, in school contexts such topics are... 相似文献
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Mary Webb Niki Davis Tim Bell Yaacov J. Katz Nicholas Reynolds Dianne P. Chambers Maciej M. Sysło 《Education and Information Technologies》2017,22(2):445-468
In this paper we have examined the position and roles of Computer Science in curricula in the light of recent calls for curriculum change and we have proposed principles and issues to consider in curriculum design as well as identifying priority areas for further research. The paper is based on discussions within and beyond the International Federation of Information Processing (IFIP) Education Community since 2012 as well as an analysis of curriculum developments in five different countries. Emerging themes have been discussed with reference to important perspectives from curriculum theory including “powerful knowledge” as a key element of entitlement and management of the growth of expertise. Based on this analysis we have identified areas of consensus as well as constraints, risks and issues that are still subject to controversy. There is an emerging consensus of the importance of Computer Science and the nature of its “powerful knowledge”. Furthermore current understanding of the opportunities and benefits for starting to learn Computer Science early in primary schools has identified this early start as an entitlement and equity issue. There is a strong consensus that teacher professional development in Computer Science Education is critical for supporting curriculum change and is currently a major challenge in many countries. Other key issues include understanding how the growth of expertise affects potential structure and sequencing in the curriculum and the balance of content. Further considerations include how new technological opportunities interact with pedagogical approaches and can provide new potential for the growth of expertise. 相似文献
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Tim McInerny 《中学生英语》2005,(12):19-19
Since high school I have always wanted to study in a country other than my own. However, my parents always informed me that it was too expensive. This was until luck turned my way one day while I was at university. My advisor called me and asked me to go and see him as soon as possible. I just knew it had to be good news. I could barely stand the suspense and went to his office with a nervous happiness in my tummy (肚子). 相似文献
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Sara Hennessy Tim O'Shea 《British journal of educational technology : journal of the Council for Educational Technology》1993,24(2):125-138
The authors discuss a key issue affecting the educational potential of interactive computer simulations—their possible lack of credibility. They explore the circumstances under which students are able to separate'magical'features from those which map easily and directly onto the real world, and the relationship between their perceptions of events on and off the computer. They put forward some means of overcoming disbelief through manipulating the degree of reality inherent in simulations and offer suggestions for how future research might address these issues. 相似文献
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The following paper outlines and evaluates the implementation of the use of peer assessment in higher education (HE), using the BA in music course at Kingston University as a case study. The rationale of the peer assessment systems introduced into two curriculum areas is examined, and the operation of the scheme is evaluated, by the use of lecturer interviews, attitudinal questionnaires completed by the participating students, and the assessments and feedback produced. Conclusions drawn are that the introduction of peer assessment seems to improve students’ critical faculties and gives them a greater ownership of the whole assessment process. 相似文献
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Instructional animation versus static pictures: A meta-analysis 总被引:8,自引:0,他引:8
A meta-analysis of 26 primary studies, yielding 76 pair-wise comparisons of dynamic and static visualizations, reveals a medium-sized overall advantage of instructional animations over static pictures. The mean weighted effect size on learning outcome is d = 0.37 (95% CI 0.25–0.49). Moderator analyses indicate even more substantial effect sizes when the animation is representational rather than decorational (d = 0.40, 95% CI 0.26–0.53), when the animation is highly realistic, e.g., video-based (d = 0.76, 95% CI 0.39–1.13), and/or when procedural-motor knowledge is to be acquired (d = 1.06, 95% CI 0.72–1.40). The results are in line with contemporary theories of cognitive load and multimedia learning, and they have practical implications for instructional design. 相似文献