试论"概念图书馆"

本文提出概念图书馆的新概念,旨在深入认识图书馆的内容性建设,强调整体性合作与发展.文中阐述了概念图书馆定义,内核和目的意义.     

一类非线性脉冲时滞差分方程的振动性

讨论非线性脉冲时滞差分方程：{xn 1-xn Pnf(Xn-l)=0,n≥0,n≠nk,xnk 1-xnk=bkxnk,k=1,2,3……给出了一类f方程所有解振动的充分条件。     

一类二阶非线性微分方程属于极限圆型的判定

主要利用Gronwall-Bellman -Behari不等式 ,把一类二阶线性微分方程与其摄动方程进行比较 ,对摄动项作适当限制 ,得到一类非线性非齐次微分方程属于极限圆型的判定准则     

Mitochondrial dysfunction at the early stage of cisplatin-induced acute renal failure in rats

The present study was undertaken to clarify the pathogenesis of cisplatin-induced acute renal failure at the early stage. Male Sprague-Dawley rats were given an intravenous administration of 10 mg/kg cisplatin. 0.9% saline was infused into them at a rate of 2 ml/h for 3 h, starting with a 2-ml bolus injection before cisplatin administration. 3 h following cisplatin administration, no evident morphological abnormalities were found by both light and electron microscopy; there were also no significant changes in GFR. Thirty min after cisplatin injection, urine sodium and potassium excretion increased by 56% and 260% those of the control animals, respectively. Apparent renal mitochondrial respiration dysfunction was observed in cisplatintreated rats 3 h later; the state 4 respiration increased by 100% and state 3 respiration, respiratory control ratio and carbonyl cyanide p-trifluoromethoxyphenyl hydrazone-uncoupled respiration decreased by 46%, 74% and 47% of the controls, respectively. The present data suggest that mitochondrial dysfunction may be a very early event in cisplatin-induced acute renal failure in rats.     

AMINO ACIDS' PROTECTIVE EFFECTS ON EXPERIMENTAL ACUTE RENAL FAILURE

This study was carried out to elucidate the nephroprotective effects from a mixture of 8 L-amino acids and the possible mechanism of protection by this amino acid mixture. Acute renal failure model was induced by an intravenous administration of 10 mg/kg cisplatin to male Sprague-Dawley rats. A mixture of 8 L-amino acids or 0.9% saline was infused at a rate of 2 ml/h for 3 h, starting with a 2 ml bolus injection before cisplatin administration. Amino acids showed no acute effect on renal morphology. The infusion of a mixture of 8 L-amino acids increased GFR by 85% in control rats. The abnormalities of urine sodium and potassium excretion caused by cisplatin were markedly attenuated by the administration of the amino acid mixture. With the infusion of this amino acid mixture, cisplatin-induced abnormal state 4 respiration returned to control levels and the depressed state 3 respiration, respiratory control ratio and carbonyl cyanide p-trifluoromethoxyphenyl hydrazone-uncoupled respiration were ameliorated remarkably. A mixture of 8 L-amino acids showed marked nephroprotection against cisplatin-induced acute renal failure in rats and might function through augmentation of the cisplatin-injured renal mitochondrial electron transport-oxidative phosphorylation sequence, probably via stabilizing the membrane (including inner mitochondrial membrane) protein tertiary structure. In addition, this amino acid mixture remarkably increased GFR and decreased urine sodium excretion in rats.     

"内化",一个被忽略的关键环节--大学生素质教育问题浅析

近年来大学生素质教育开展得轰轰烈烈,然而其效果却并不如人们所预期的那样好,恐怕与大学忽略了素质教育过程中“内化”这一关键环节不无关系。在某种程度上我们甚至可以说,大学教育缺乏促进素质教育要求转化为学生内在身心素质的条件与措施,是大学生素质教育功亏一篑...     

国际突发公共事件背景下大学生社会主义核心价值观培育探究

当前国际性突发公共事件频发,它不仅具备一般突发公共事件的突发性、破坏性、不可预见性、紧迫性等特点,且因其爆发的范围不仅限于我国范围内,而是涉及到不同文化、价值观的人群和不同制度体系的国家,影响程度远超一般突发公共事件,治理难度更大,影响也更为深远.当前大学生由于能够较好地使用信息技术、社会主人翁意识较强等特点,对于国际...     

用ISTP统计评估国际学术会议的等级

利用科技会议录索引ISTP,从会议主办机构、ISTP收录会议论文篇数和专家审定等三方面对ISTP收录的国际学术会议进行等级评估。评估结果为按学校学科专业、会议等级、会议名称等排列的EXCEL表。结果表明这种方法能定量与定性评估国际学术会议的等级。参考文献2.     

D-S证据理论在群决策支持系统中的应用

针对以往决策方法的不足,运用D-S证据理论融合处理多个决策的结果,以提高准确性与可靠性,辅助做出科学化的决策,以完善建立群决策支持系统。     

精表处预养护沥青路面耐磨耗性能研究

为研究新型精表处预养护沥青路面的耐磨耗性能,以自制高性能胶结料和三种粒径的玄武岩为原材料研究了不同集料粒径、油石比以及胶结料洒布量对精表处沥青路面层耐磨性能的影响,对不同试件进行4个周期的磨耗试验,测定了不同磨耗周期下精表处试件的质量损失、构造深度和摩擦系数.试验结果表明,经过精表处技术处理后的路面改善效果较好,精表处...