Preparation and evaluation of microcapsule containing volatile oil of Herba Schizonepetae by emulsion solvent diffusion method

Microcapsules of volatile oil containing Herba Schizonepetae(VOHS) were prepared by emulsion solvent diffusion method to improve the drug loading and reduce the amount of pharmaceutical excipients.Orthogonal assay was applied to optimize the preparation condition of microcapsulation,and the results illustrated that the ratio of ethyl cellulose(EC) to VOHS influenced the property of VOHS microcapsule significantly.GC-MS analysis indicated that some volatile components with low concentration in VOHS were lost after microencapsulation.The microcapsules prepared with optimum condition had good fluidity,and the holes on the surface of the microcapsules contributed to the release of VOHS.The particles of the microcapsule conformed to a normal distribution with the diameter of 45—220 μm.In the simulated intestinal fluid containing 0.2% sodium dodecyl sulfate,pulegone in VOHS microcapsule showed a certain degree of slow release.Compared with β-cyclodextrin method,the microencapsulation used in the present work could reduce the amount of excipients and increase the drug loading.It was beneficial to reduce the dose of Chinese medicines containing volatile oils.     

K-12 students’ online learning motivation in China: An integrated model based on community of inquiry and technology acceptance theory

Education and Information Technologies - Learning motivation is crucial to online learning success, especially for K-12 students. Although previous research has proved that there are many factors...     

幼儿园园本课程资源开发存在的问题及对策

当前园本课程资源开发利用存在着水平低、结构单一、目的性不强等问题,这些问题的原因是教师缺乏课程资源开发的综合知识与能力,幼儿园缺乏民主、开放的管理制度。园本课程开发利用的对策是：加强对教师的多层化多样化培训、合理建构和优化园本课程资源的结构、重视教学在课程资源开发中的积极作用。     

1995-1999年国内外同类期刊论文中图表数量的比较

比较并分析了1995-1999年出版国内外5种同类学术期刊论文中的统计图和统计表的数量。结果表明，国内学术期刊的论文中统计图太少，统计表过多。提示这些学术期刊论文的科学含量较少，可利用的资料不多，与国外同类学术期刊相比，差距较大。     

基于任务驱动的“电工学”教学设计

本文阐述了任务驱动教学法的基本环节、在电工学中的实际应用以及使用该方法时要注意的问题。     

湖南省专利结构分布及其区域变动模式研究

从专利发展速度、授权率、专利结构分析了湖南省专利发展的总体情况,并利用布局系数和顺序分布模型,从区域特化角度分析了近年来湖南省各地区专利结构区域分布和变动的差异,最后针对湖南省专利发展特点,提出了一些建议.     

化学基础实验教学方法的思考与探索实践

为了培养高素质创新型人才以适应新时期国家建设和社会发展的需要,高等教育正进行着全面的改革。如何进一步深化教学改革,提高教学质量,加快高等教育强国的建设步伐,高等教育教学方法的改革与创新至关重要。本文就在化学基础实验教学中对教学方法的思考和点滴实践进行了初步的总结。     

Validity and reliability testing of the Chinese (mainland) version of the 39-item Parkinson’s Disease Questionnaire (PDQ-39)

The 39-item Parkinson’s Disease Questionnaire (PDQ-39) has been tested in many languages, but not in Chinese mainland. We aimed to assess the Chinese (mainland) version of the PDQ-39. Seventy-one subjects with Parkinson’s disease (PD) completed the PDQ-39 and the Medical Outcomes Study 36-item Short Form Health Survey (SF-36). All subjects were retested with the PDQ-39 a week later. The united Parkinson’s disease rating scale (UPDRS) and the Hoehn and Yahr (H &; Y) scale were also used to evaluate the subjects. Reliability was assessed by Cronbach’s α and intra-class correlation coefficient (ICC). Validity was examined in terms of agreement with SF-36, UPDRS, and H &; Y scales. The Chinese (mainland) version of the PDQ-39 demonstrated acceptable reliability (Cronbach’s α: 0.84–0.88; ICC: 0.56–0.82). The item-total correlations (0.33–0.88) and scaling success rates (77.56%) indicated satisfactory convergent and discriminant validity of the PDQ-39 items. The correlations between related constructs of the PDQ-39 and UPDRS (r=0.44–0.68) and between those of the PDQ-39 and SF-36 (r=(−0.46)-(−0.69)) were all statistically significant (P<0.01). Except for stigma, cognitions, and bodily discomfort, all other dimensions of the PDQ-39 significantly discriminated patients at different H &; Y stages indicated by the H &; Y scale. Although our observations indicate that some problematic subscales of this version of the PDQ-39 could be improved upon, this study suggests acceptable reliability and validity of the Chinese (mainland) version of the PDQ-39.     

母子山村人地关系优化调控对策

根据母子山村实地调研结果分析：该村人口众多,贫困现象突出,人地关系矛盾突出.要使这一地区贫困状况得到根本性的改善,人地关系优化,就应该对这一地区的产业结构.