以校为本:院校研究的核心价值取向

对我国而言,院校研究是高等教育的一个新的研究领域、一种新的研究范式,开启了专门研究某所具体高等院校的新的实践活动形式。本文从院校研究的动因是学校自身的发展,院校研究的对象是具体的学校自身,院校研究的内容是本校实际问题,院校研究的主体是本校人员等四个方面来探讨、说明“以校为本”是院校研究的核心价值取向,以期为我国的院校研究提供一个新的视角。     

公文、志书文风共性浅析

公文、志书虽不属同一文体,但其文风有共性之处,本文试从"严谨、朴实、简洁、流畅"及略带文采几方面对此进行剖析.     

教育的终极目的——关注人的生存状态

通过对教育终极目的的认识,分析了多种关于教育终极目的的论点.揭示了这些论点具有共同的基础,即教育是一门生存的艺术,它的终极目的应为关注人的生存状态.     

我国小学生道德情感发展研究述评与展望

小学生道德情感发展的研究是德育心理学研究领域的重要组成部分之一.本文从研究工具、关键期、移情发展、道德情绪判断四个方面总结了我国10余年来在该领域的研究,阐述了研究存在的不足,并对研究的未来做了展望     

华县东阳西周墓地结构研究

东阳西周墓地可划分为不同族属的两类四个墓区,包含殷遗民与东阳主体族群,后者可能原为活动于甘肃东部地区的西土古族,或因灭商有功,于周初改封畿内,并被分赐以殷遗民.墓地内的墓葬按族属、等级分墓区而葬,表明血缘关系是其社会组织的基础,族群内与族群间的等级差异又体现了宗法等级制度及族群关系的政治等级化.其统治族群结合殷遗民的族...     

大众化过程中高等教育自学考试的作用和发展

我国高等教育已经实现了大众化。在大众化过程中,高等教育自学考试起到主力军的作用。在大众化条件下,高等教育自学考试向高等职业教育方向发展。目前这种趋势主要表现在开设应用技术型专业、推行双证书教育模式、突出就业功能、重视对毕业生的就业指导工作等方面。     

Replication,pathogenicity, and transmission of SARS-CoV-2 in minks

Minks are raised in many countries and have transmitted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to humans. However, the biologic properties of SARS-CoV-2 in minks are largely unknown. Here, we investigated and found that SARS-CoV-2 replicates efficiently in both the upper and lower respiratory tracts, and transmits efficiently in minks via respiratory droplets; pulmonary lesions caused by SARS-CoV-2 in minks are similar to those seen in humans with COVID-19. We further found that a spike protein-based subunit vaccine largely prevented SARS-CoV-2 replication and lung damage caused by SARS-CoV-2 infection in minks. Our study indicates that minks are a useful animal model for evaluating the efficacy of drugs or vaccines against COVID-19 and that vaccination is a potential strategy to prevent minks from transmitting SARS-CoV-2.     

Injectable hybrid inorganic nanoscaffold as rapid stem cell assembly template for cartilage repair

Cartilage injuries are often devastating and most cannot be cured because of the intrinsically low regenerative capacity of cartilage tissues. Although stem-cell therapy has shown enormous potential for cartilage repair, the therapeutic outcome has been restricted by low survival rates and poor chondrocyte differentiation in vivo. Here, we report an injectable hybrid inorganic (IHI) nanoscaffold that facilitates fast assembly, enhances survival and regulates chondrogenic differentiation of stem cells. IHI nanoscaffolds that strongly bind to extracellular matrix (ECM) proteins assemble stem cells through synergistic 3D cell–cell and cell–matrix interactions, creating a favorable physical microenvironment for stem-cell survival and differentiation in vitro and in vivo. Additionally, chondrogenic factors can be loaded into nanoscaffolds with a high capacity, which allows deep, homogenous drug delivery into assembled 3D stem-cell-derived tissues for effective control over the soluble microenvironment of stem cells. The developed IHI nanoscaffolds that assemble with stem cells are injectable. They also scavenge reactive oxygen species and timely biodegrade for proper integration into injured cartilage tissues. Implantation of stem-cell-assembled IHI nanoscaffolds into injured cartilage results in accelerated tissue regeneration and functional recovery. By establishing our IHI nanoscaffold-templated 3D stem-cell assembly method, we provide a promising approach to better overcoming the inhibitory microenvironment associated with cartilage injuries and to advance current stem-cell-based tissue engineering.     

多校区大学的规模经济、范围经济与联结经济

高效的多校区大学管理不仅可以带来规模经济和范围经济优势,而且可以带来联结经济优势。多校区大学的规模经济优势主要在于相同校区的互融,范围经济优势主要在于相异校区的互补,联结经济优势主要在于相近校区的互通。多校区大学的经济效益主要受校区数量、各校区的办学能力、校区间的相似程度、校区间的互赖关系、校区间的共享能力等因素影响。     

以复杂思维透视道德教育的研究和实践

复杂思维是复杂科学在社会科学研究中的认识论和方法体系。以复杂思维透视道德教育改革,必须在开放的理性指导下,寻求支撑性的文化根基;建立生命的科学,寻找道德教育迷失的主体;运用复杂范式,建立起道德教育的多学科统整的研究范式。