Organic-inorganic material for the consolidation of plaster

Organic-inorganic materials to be used as hydrophobic consolidants for plasters were synthesized starting from an inorganic precursor (Tetraethoxysilane [TEOS]), added to a polysiloxane epoxy formulation and thermally cured with Ytterbium as acid catalyst. The TEOS reduces the viscosity of the resin, contributing to the mechanical properties of the film, without causing cracking. Solvents, that are harmful for workers and environment and show some drawbacks in the practice of restoration, were not used. The film properties and the formation of silica clusters were investigated. The products were applied by brush on plaster's samples and their compatibility and effectiveness were verified. Thanks to the organic content, the products penetrate deeply, are more stable to photo-oxidative degradation, and the hydrophobicity of the resin, provided by the silicone component, is not altered.     

Cardiac indexes, cardiac damage biomarkers and energy expenditure in professional cyclists during the Giro d'Italia 3-weeks stage race

Introduction

The study of cardiac response to strenuous and continuous exercise is crucial to understanding the physiology of endurance. N-terminal proB-type natriuretic peptide (NT-proBNP) is a potential marker for monitoring myocardial wall stress, and troponins (TnT and TnI) are widely used in the diagnosis of cardiac ischemia and infarction. Strenuous exercise may generate transitory ischemia, myocardial stress, and diastolic left ventricular dysfunction, inducing the increased production of both these biomarkers. We measured changes in NT-proBNP and TnT in elite cyclists during a 3-week stage race, a model of strenuous exercise.

Materials and methods:

The study population was 9 professional cyclists participating in the 2011 Giro d’Italia. Pre-analytical and analytical phases scrupulously followed official recommendations. Anthropometric data, net energy expenditure and cardiac indexes (rate, diastolic and systolic blood pressure) were recorded. Blood samples were drawn pre-race (day −1) and at days 12 and 22; NT-proBNP and highly sensitive-troponin (Hs-TnT) concentrations were assayed and corrected for plasma volume changes.

Results:

Body-mass index decreased and energy expenditure increased by 52% during the race. NT-proBNP concentrations increased [day −1: 23.52 ng/L (9.67–34.33); day 12: 63.46 ng/L (22.15–93.31); P = 0.039; day 22: 89.26 ng/L (34.66–129.78) vs. day −1; P < 0.001] and correlated with heart rate (r = −0.51; P = 0.006), systolic pressure (r = 0.39; P = 0.046) and energy expenditure (r = 0.70; P < 0.001). TnT concentrations did not vary, but a widened TnT amplitude distribution was observed.

Conclusions:

Increases in NT-proBNP correlated with higher energy expenditure over a 3-week cycling stage race, possibly indicating myocardial stress.     

Mapping the impact of climate change on biomass accumulation on stone

Several climate parameters affect the growth of organisms and, hence, their capacity to accumulate biomass. In the present research, we analyse the influence of two parameters, temperature and precipitation, on biomass accumulation on stone substrate, and propose a function to estimate it in temperate areas. The expression is subsequently used for the first time to evaluate the impact that climate change would have in biomass accumulation in Europe. The models on climate change predict an increase in temperature and precipitation in northern areas of Europe for the far future (2070–2099), which would lead to a higher accumulation of biomass. Otherwise, a significant reduction in precipitation is expected in southern areas of Europe, associated with a lower biomass accumulation in such areas.     

Neuroanatomy,the Achille’s Heel of Medical Students. A Systematic Analysis of Educational Strategies for the Teaching of Neuroanatomy

Neuroanatomy has been deemed crucial for clinical neurosciences. It has been one of the most challenging parts of the anatomical curriculum and is one of the causes of “neurophobia,” whose main implication is a negative influence on the choice of neurology in the near future. In the last decades, several educational strategies have been identified to improve the skills of students and to promote a deep learning. The aim of this study was to systematically review the literature to identify the most effective method/s to teach human neuroanatomy. The search was restricted to publications written in English language and to articles describing teaching tools in undergraduate medical courses from January 2006 through December 2017. The primary outcome was the observation of improvement of anatomical knowledge in undergraduate medical students. Secondary outcomes were the amelioration of long-term retention knowledge and the grade of satisfaction of students. Among 18 selected studies, 44.4% have used three-dimensional (3D) teaching tools, 16.6% near peer teaching tool, 5.55% flipped classroom tool, 5.55% applied neuroanatomy elective course, 5.55% equivalence-based instruction-rote learning, 5.55% mobile augmented reality, 5.55% inquiry-based clinical case, 5.55% cadaver dissection, and 5.55% Twitter. The high in-between study heterogeneity was the main issue to identify the most helpful teaching tool to improve neuroanatomical knowledge among medical students. Data from this study suggest that a combination of multiple pedagogical resources seems to be the more advantageous for teaching neuroanatomy.     

From parents to children: the impact of mothers’ and fathers’ educational attainments on those of their sons and daughters in West Germany

Empirical studies have repeatedly shown that in Germany educational success still strongly depends on the social origin of individuals. Using the National Educational Panel Study, we analyse the effects of fathers’ and mothers’ education levels on their sons’ and daughters’ educational attainments across three successive birth cohorts in West Germany. We calculate the predicted probabilities of reaching low, medium or high education levels on the basis of the level of education of the mothers and the fathers. Our results show: a persistence of the status maintenance model, with very few exceptions; a growth in the educational level of women via medium-level education connected to segregation in the labour market; and finally that the first transition of girls to medium-level education has been completed, leaving space for daughters to attempt to outnumber sons in tertiary education, mainly due to the pressure of mothers.     

The market for patents in Europe

By using the PatVal-EU dataset we find that the most important determinant of patent licensing is firm size. Patent breadth, value, protection, and other factors suggested by the literature also have an impact, but not as important. In addition, most of these factors affect the willingness to license, but not whether a license actually takes place. We discuss why this suggests that there are transaction costs in the markets for technology. The issue is important because many potential licenses are not licensed suggesting that the markets for technology can be larger, with implied economic benefits.     

An analysis of building methods: chemical-physical and archaeological analyses of micro-layer coatings on medieval facades in the centre of Genoa

The present research is an attempt to create a link among different disciplines and to confirm stratigraphic observations through chemical analyses. It involved detailed colorimetric examination and in-depth chemical-physical study of the samples taken from the historical centre of Genoa, which enabled connections to be made among many data. This led to the creation of an analytical method that is applicable to various geographical sites. Examinations involved several experimental techniques: X-ray diffractometry, scanning electron microscopy, optical microscopy and infrared spectroscopy; the data were compared with those from the stratigraphic examination. A detailed investigation of the Ligurian climate, including data kindly supplied by the Environment Department of the Provincia di Genova, allowed us to explain the presence of particular chemical substances and suggested how they might have been formed.     

Varied but not necessarily random: Human performance under variability contingencies is affected by instructions

The goal of the present study was to evaluate the role of verbal stimuli in the production of response variability in humans. College students were distributed into three groups and asked to type three-digit sequences. Participants in the systematic group were instructed to produce sequences according to a rule of their choice; those in the random group were instructed to produce sequences according to chance; and those in the control group were not instructed about how to produce sequences. The experiment employed an ABA design. During the A phases, low-frequent sequences were reinforced (variability contingency), whereas during the B phase, reinforcement was withdrawn (extinction). The results indicated the following: (1) The instructions were efficient at producing systematic and random-like patterns for the systematic and random groups, respectively; in the absence of instructions, a mix of both patterns was observed. (2) Behavior was sensitive to extinction independently of the instructions provided. (3) Systematic patterns favored a more equiprobable distribution of sequences across trials. (4) Reaction times were longer for responding in a systematic than in a random-like fashion. The present findings suggest that individual differences in meeting variability contingencies may be due, at least partially, to instructional control.