3 = 1 + 2: how the divide conquered de novo protein structure prediction and what is next?

<正>Protein structure prediction has been a challenging problem for>60 years. Its progress has been considered incremental for the past 20 years until leaps were made by Alpha Fold that seemed to suddenly reach experimental accuracy. We argue that this unexpected success in 3D structure prediction was foreshadowed by prior advances in predicting 1D backbone structures and 2D side-chain distance maps in continuous angle and distance space as well as the embedding of these 1D and 2D featur...     

High-efficiency nonlocal reflection-type vortex beam generation based on bound states in the continuumOA

Momentum-space polarization vortices centered at symmetry-protected bound states in the continuum of a periodic structure,e.g.photonic crystal slab,provide a novel nonlocal approach to generate vortex beams.This approach enjoys a great convenience of no precise alignment requirements,although the generation efficiency of the nonlocal generators requires further optimization before the practical application.In this work,we propose a temporal-coupled-mode-theory-based guideline for high-efficiency...     

电子政务中的信息资源整合

电子政务建设对信息产业提出的需求是资源的整合,把各个隔绝的系统和分散的资源整合起来,是我国当前信息化建设的中心课题。对于电子政务系统而言。多层次的整合架构是大规模信息化应用成功的必要条件和关键因素。本文分四个层次论述了电子政务资源整合的目标、方法和实现技术。     

试论高职院校发展存在的问题及对策

高职教育已经成为高等教育的重要组成部分,近年来,高职教育发展迅速,学校数量快速增长,办学规模迅速扩大,办学途径不断拓宽,必将对我国经济建设起到积极的推动作用。但在发展过程中仍然存在着诸如规模、质量、特色、投入机制、师资建设等方面的问题,只有解决好这些问题,才能促使高职院校持续、健康、快速发展。     

高校辅导员队伍建设的困境及对策

近年来,高校辅导员队伍面临着不少困境,原因是多方面的。本文调查列举了影响高校辅导员队伍战斗力的一些因素,分析了其形成的原因,并提出了加强高校辅导员队伍建设的相应对策。     

论青年自我实现功能及方法的把握

本文用马克思主义的自我实现论,阐述了青年自我实现的若干功能,并介绍了当代青年如要最大限度地实现自我,必须掌握正确的方法,从而达到个体的自我实现和社会的自我实现高度统一的目的.     

论新时期道德修养

论述市场经济条件下道德修养的重要性 ,指明进行道德修养的四种途径 :要认识真理并不懈地追求真理 :要把祖国利益放在第一位 ;与他人建立互助式的人际关系 ;正确认识自我并严于律己、宽以待人。通过道德修养 ,不断完善自我 ,才能成为新时期社会主义建设的有用人才     

Photonic orbital angular momentum with controllable orientationOA

Vortices are whirling disturbances,commonly found in nature,ranging from tremendously small scales in Bose-Einstein condensations to cosmologically colossal scales in spiral galaxies.An optical vortex,generally associated with a spiral phase,can carry orbital angular momentum(OAM).The optical OAM can either be in the longitudinal direction if the spiral phase twists in the spatial domain or in the transverse direction if the phase rotates in the spatiotemporal domain.In this article,we demonstra...     

Dynamic bandwidth allocation scheme for MCNS DOCSIS

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