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81.
82.
Justin X. Nicoll Andrew J. Galpin Donald B. Thomason Christopher A. Moore 《European Journal of Sport Science》2017,17(9):1194-1202
Purpose: There is a paucity of research investigating the expression of mitogen-activated protein kinases (MAPK) in chronically trained (CT) athletes. Thus, it is unclear how MAPK may contribute to performance and muscle adaptation in CT subjects. The purpose of this study was to determine MAPK total protein, and phosphorylated expression of extracellular signal-regulated kinases 1 and 2 (ERK1/2), c-Jun N-terminal kinase (JNK), and p38-MAPK (p38) between untrained, and chronically trained runners. Methods: Tissue samples were analysed from sedentary (SED; n?=?5) controls and chronically trained runners (CT; n?=?5). Resting muscle biopsy samples were analysed for total-MAPK – and ratio of phosphorylated/total (p-MAPK) – ERK1/2, JNK, and p38-MAPK via western blotting. Mann–Whitney U tests and effect sizes were utilized to determine differences in total MAPK protein content and phosphorylation status between SED and CT subjects. Results: There was no difference in total-MAPK expression between SED and CT (p?>?.05). p-p38-MAPK tended to be greater for CT compared to SED (p?=?.07). There were moderate effect sizes of decreased pERK/total-ERK (d?=??0.69) and increased pJNK/total-JNK (d?=?0.54) in CT compared to SED. There was a positive correlation between p-p38-MAPK/total-MAPK and the percentage of type I fibres (r?=?0.73, p?=?.016). Conclusion: Contrary to previous studies, chronic endurance training does not greatly influence total MAPK protein expression in chronically trained runners. However, resting phosphorylation of p38-MAPK may contribute to enhanced oxidative metabolism at chronically trained levels. These alterations are likely involved in the different physiological adaptations that occur following long-term training or at highly competitive levels. 相似文献
83.
Peter B. Smith Cláudio V. TorresAlena Chudzikova Serdar DegirmenciogluFrancisco Donoso-Maluf Nancy Chen Yi FengCharles Harb Brad JacksonSigmar Malvezzi Andrew MogajiJuan Carlos Pastor Lorena Perez-FlorianoB.N. Srivastava Günter StahlStephanie Thomason Vladimir Yanchuk 《Int J Intercult Relat》2011,35(4):440-451
84.
Ullah SM Bodrogi A Cristea O Johnson M McAlister VC 《Anatomical sciences education》2012,5(3):165-170
Didactic and laboratory anatomical education have seen significant reductions in the medical school curriculum due, in part, to the current shift from basic science to more clinically based teaching in North American medical schools. In order to increase medical student exposure to anatomy, with clinical applicability, a student-run initiative called surgically oriented anatomy prosectors (SOAP) club was created within the extracurricular program at the Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Canada. SOAP invites surgeons and residents from various surgical specialties to demonstrate, on a cadaver, a surgical procedure of their choosing. During the demonstration, the anatomy, as it relates to the surgical procedure, is discussed. The students then break into smaller groups to examine the relevant anatomy on the cadavers, during which time the discussion is broadened. The group continues the conversation in a social environment with refreshments. SOAP is one of the most popular extracurricular clubs with 65% of first and second year medical students registered as members. The high demand for SOAP, along with the positive participant feedback, may be due to its utilization of the principle of education through recreation, which seeks to provide opportunities for learning seamlessly throughout all facets of life. It also demonstrates the desire, amongst certain medical students, to learn applied anatomy, particularly within a surgical context. 相似文献
85.
Government-led interorganizational alliance networks present a sensible opportunity to overcome many societal challenges through collaborative governance. In particular, few researchers have studied alliance networks in the field of energy conservation in commercial buildings—a sector with unique barriers to greater diffusion of innovative cost-saving strategies. We applied an analytic inductive case-based method and social network analysis to study one particular alliance network: the United States Commercial Building Energy Alliances representing interests from retail, commercial real estate, and healthcare sectors. This alliance network was initiated by the United States Department of Energy, with assistance from several federally funded research laboratories in the United States, to promote the diffusion of knowledge and ultimately encourage greater deployment of energy efficiency and clean energy strategies in commercial buildings. We draw upon interview data from 28 cases of private, non-profit, and governmental organizations and complete network data from the alliance participants. We honed in on eight focal cases of governmental organizations to provide insight on how the four forms of energy and environmental data, information, and knowledge shared within an alliance network address the challenge of a vastly underutilized energy resource, namely conservation. Further, we identify and discuss the public's four roles—Commissioner, Interpreter, Marketer, and User—in providing balance to the diffusion of both private and public goods in a network. 相似文献
86.
The purpose of this study was to investigate social science doctoral students’ preferences and needs with regard to written feedback on academic writing and to develop a written feedback categorization. In an exploratory mixed methods approach, qualitative data collected during interviews were used to form a questionnaire to collect quantitative data in two research-intensive universities. The results based on 276 doctoral students’ responses provided a clear list of feedback types needed by doctoral students, including comments addressing their main idea, argumentation, clarity, and information coverage. Their preferences varied on issues of autonomy, criticism, and ambiguity, all critical factors in the transition to independence expected during their doctoral education. The resulting written feedback categorization encompasses three aspects: function, focus, and presentation. The findings of this study have the potential to guide supervisors, feedback providers, and doctoral students as well as inform further research, including instrument development and written feedback content analyses. 相似文献
87.
Explaining the academic performance of community college students who transfer to a senior institution 总被引:1,自引:1,他引:1
Archie G. Phlegar Loyd D. Andrew Gerald W. McLaughlin 《Research in higher education》1981,15(2):99-108
The academic performance of 361 community college students was investigated after their transfer to a comprehensive university. The predictor variables included personal, environmental, demographic, and pretransfer academic measures. The criterion was grade point average (GPA) at the senior institution. Analyses included moderated linear regression and a branching algorithm which forms subgroups to best explain criterion scores (AID-3). The academic pattern and performance at the community college was found to be very important to the relevance of specific factors related to the curriculum selected at the senior institution. 相似文献
88.
Jack E. T. Wells Andrew C. S. Mitchell Laura H. Charalambous Iain M. Fletcher 《Journal of sports sciences》2018,36(16):1847-1851
Whilst previous research has highlighted significant relationships between golfers’ clubhead velocity (CHV) and their vertical jump height and maximum strength, these field-based protocols were unable to measure the actual vertical ground reaction force (vGRF) variables that may correlate to performance. The aim of this study was to investigate relationships between isometric mid-thigh pull (IMTP), countermovement jump (CMJ), squat jump (SJ) and drop jump (DJ) vGRF variables and CHV in highly skilled golfers. Twenty-seven male category 1 golfers performed IMTP, CMJ, SJ and DJ on a dual force platform. The vertical jumps were used to measure positive impulse during different stretch-shortening cycle velocities, with the IMTP assessing peak force (PF) and rate of force development (RFD). Clubhead velocity was measured using a TrackMan launch monitor at a golf driving range. Pearsons correlation coefficient analyses revealed significant relationships between peak CHV and CMJ positive impulse (r = 0.788, p < 0.001), SJ positive impulse (r = 0.692; p < 0.001), DJ positive impulse (r = 0.561, p < 0.01), PF (r = 0.482, p < 0.01), RFD from 0–150 ms (r = 0.343, p < 0.05) and RFD from 0–200 ms (r = 0.398, p < 0.05). The findings from this investigation indicate strong relationships between vertical ground reaction force variables and clubhead velocity. 相似文献
89.
Two studies examine reactions to permitted (offered and permission granted), volunteered (given without offer or assent), and imposed advice (offered and given even though declined). In Study 1, participants’ ratings of advice quality and implementation intention were higher for volunteered and permitted than imposed advice. Only for a task that was highly personal did recipients have a significantly higher intention to use permitted than volunteered advice. Study 2 replicated results from Study 1 with a nonstudent sample. In addition, Study 2 found stronger differences between volunteered and permitted advice, with permitted advice rated more positively. Study 2 also examined the effect of using you pronouns, which have been linked to confrontation and criticism, when giving advice, but found no consistent effects on advice outcomes. 相似文献
90.
Brad Benedict Linda Barton George McCue Dean Tudor Andrew D. Armitage Derek Jewell 《Communication Booknotes Quarterly》2013,44(3):55-57
Brad Benedict and Linda Barton's Phonographics: Contemporary Album Cover Art and Design (New York: Collier Books/Macmillan Publishing, 1977—$9.95, paper) George McCue, ed. Music in American Society, 1776-1976: From Puritan Hymn to Synthesizer (New Brunswick, N.J.: Transaction Inc., 1977—$14.95/3.95) Dean Tudor and Andrew D. Armitage, comps. Popular Music Periodicals Index, 1975 (Metuchen, N.J.: Scarecrow Press, 1976—$15.00) Derek Jewell, Duke: A Portrait of Duke Ellington (New York: Norton, 1977—$9.95) Stanley Dance, The World of Earl Hines (New York: Scribner's, 1977—$14.95/7.95 相似文献