Kidney function change after transcatheter aortic valve replacement in patients with diabetes and/or hypertension

Aortic stenosis(AS)is a progressive heart valve disease occurring predominantly in older patients.According to a survey in a western country,the prevalence of AS is nearly 6.4%in patients over 75 years old(Carabello and Paulus,2009).Transcatheter aortic valve replacement(TAVR)is an alternative method for AS patients.Previous studies have described how up to 66%of TAVR patients have concomitant baseline kidney dysfunction(Ferro et al.,2015;Gargiulo et al.,2015).The majority of patients can benefit from the TAVR procedure with the recovery of kidney function.     

What predicts the malnutrition among a select group of Filipino older persons in institutionalized setting? A partial least square study

The overall intent of this study is to examine the relationship among several factors that influence the malnutrition of a select group of Filipino elderly in institutionalized setting. A total of 102 residents were purposively recruited from three different institutionalized care settings at the national capital region of the Philippines. A multi-aspect questionnaire was used to characterize the demographic and nutrition profiles of the participants. Data were treated statistically using the partial least square design. Notably, the study showed that 48.0% of the elderly residents in institutions were at risk of malnutrition, 36.3% were malnourished, and 15.7% have normal nutritional status. Malnutrition was found to be prevalent among the female group, aged >70 years old, functional impairment (p = <0.01), poor eating habits (p = 0.01), lower dietary intake (p = 0.01), and eating difficulties (p = 0.04). However, statistically significant relationships between eating habits (p = 0.08) and dietary intake and comorbidities (p = 0.32) and malnutrition were not established. Impliedly, administrators of homecare institutions are invited to pay greater attention to the nutritional status of the elderly by institutionalizing nutrition assessment and evaluation practices and nutrition care planning that respond to the identified nutritional needs and concern of the elderly.     

Early Cerebral Constraints on Reading Skills in School‐Age Children: An MRI Study

Reading relies on a left‐lateralized network of brain areas that include the pre‐lexical processing regions of the ventral stream. Specifically, a region in the left lateral occipitotemporal sulcus (OTS) is consistently more activated for visual presentations of words than for other categories of stimuli. This region undergoes dramatic changes at the functional and structural levels when children learn to read, but little is known about the effects of early cerebral constraints on reading skills. Using anatomical magnetic resonance imaging, we investigated whether the sulcal pattern of the lateral OTS—a stable brain feature—was associated with oral reading skills. The sulcal pattern of the left but not the right lateral OTS was associated with the number of words correctly read in 3 min. This study is the first to evidence that reading is affected by early cerebral constraints, such as the sulcal morphology of the left lateral OTS.     

Generalization of serial learning in the pigeon

Sequence learning in pigeons was studied in asimultaneous chaining paradigm: all stimuli and the opportunity to respond to each stimulus were available simultaneously. In contrast to the traditionalsuccessive chaining paradigm, a simultaneous chaining paradigm provides no differential feedback following each response (except the last). Subjects were first trained to perform on sequences of two (AB), then three (ABC), and then four colors (ABCD). Performance greatly exceeded that predicted by models of random choice. Generalization to novel arrays of three and four colors was complete. After training with a four-color sequence, the subjects were tested with subsequences consisting of all possible combinations of two and three of the four training colors (e.g., BD, AD, BC, ACD, BCD, etc.). The successful completion of these subsequences showed that the organization of the original sequence did not entail overt pecks to successive elements of that sequence. That subjects can respond accurately on nonadjacent subsets is not readily explained by a chaining theory, or by any theory that assumes that responding to element n provides a cue for responding to element n+1.     

The professionalisation of teaching: teacher training and education reform in Austria, 1867–1914

This article examines Austria’s efforts to reform teacher education during the period of the Dual Monarchy, 1867–1914. It offers insight into the role of teachers in Austrian society and how this role changed over time. It demonstrates that, during this period, teaching became an institutionalised and professionalised occupation. This process of professionalisation brought teachers firmly under state control, leading to conflict between teachers and the Austrian educational bureaucracy. This process also led to the development of a robust network of teachers’ associations to represent the interest of Austrian teachers and to contribute to their professional development. This article utilises documents from the Austrian educational bureaucracy, printed curriculum and pedagogical journals to illustrate that Austrian teacher training reforms offer crucial insight into the development of public education in the late nineteenth century.     

A Typology of State Financial Aid Grant Programs Using Latent Class Analysis

Research in Higher Education - State financial aid grant programs are commonly categorized as either need-based, merit-based, or both, but their initial eligibility requirements include many more...     

An improved method for computing Hankel transform

The purpose of this paper is to compute the Hankel transform F_n(y) of order n of a function f(x) and its inverse transform using rationalized Haar wavelets. The integrand is replaced by its wavelet decomposition. Thus representing F_n(y) as a Fourier-Bessel series with coefficients depending strongly on the local behavior of the function , thereby getting an efficient algorithm for their numerical evaluation. Numerical evaluations of test functions with known analytical Hankel transforms illustrate the proposed algorithm.     

Bandpass sorting of heterogeneous cells using a single surface acoustic wave transducer pair

Separation and sorting of biological entities (viruses, bacteria, and cells) is a critical step in any microfluidic lab-on-a-chip device. Acoustofluidics platforms have demonstrated their ability to use physical characteristics of cells to perform label-free separation. Bandpass-type sorting methods of medium-sized entities from a mixture have been presented using acoustic techniques; however, they require multiple transducers, lack support for various target populations, can be sensitive to flow variations, or have not been verified for continuous flow sorting of biological cells. To our knowledge, this paper presents the first acoustic bandpass method that overcomes all these limitations and presents an inherently reconfigurable technique with a single transducer pair for stable continuous flow sorting of blood cells. The sorting method is first demonstrated for polystyrene particles of sizes 6, 10, and 14.5 μm in diameter with measured purity and efficiency coefficients above 75 ± 6% and 85 ± 9%, respectively. The sorting strategy was further validated in the separation of red blood cells from white blood cells and 1 μm polystyrene particles with 78 ± 8% efficiency and 74 ± 6% purity, respectively, at a flow rate of at least 1 μl/min, enabling to process finger prick blood samples within minutes.     

Size-dependent trajectories of DNA macromolecules due to insulative dielectrophoresis in submicrometer-deep fluidic channels

In this paper, we demonstrate for the first time that insulative dielectrophoresis can induce size-dependent trajectories of DNA macromolecules. We experimentally use λ (48.5 kbp) and T4GT7 (165.6 kbp) DNA molecules flowing continuously around a sharp corner inside fluidic channels with a depth of 0.4 μm. Numerical simulation of the electrokinetic force distribution inside the channels is in qualitative agreement with our experimentally observed trajectories. We discuss a possible physical mechanism for the DNA polarization and dielectrophoresis inside confining channels, based on the observed dielectrophoresis responses due to different DNA sizes and various electric fields applied between the inlet and the outlet. The proposed physical mechanism indicates that further extensive investigations, both theoretically and experimentally, would be very useful to better elucidate the forces involved at DNA dielectrophoresis. When applied for size-based sorting of DNA molecules, our sorting method offers two major advantages compared to earlier attempts with insulative dielectrophoresis: Its continuous operation allows for high-throughput analysis, and it only requires electric field strengths as low as ∼10 V∕cm.