Microfluidic generation of PEG-b-PLA polymersomes containing alginate-based core hydrogel

Herein, we demonstrate a novel method for the generation of monodisperse cell-like structures containing a biocompatible hydrogel matrix surrounded by a membrane responsive to chemical cues. Specifically, we employ droplet-based microfluidics to generate PEG-PLA polymersomes encapsulating alginate in liquid form. We investigate alginate core gelation by creating an osmotic pressure gradient across the polymeric membrane that, through expansion, allows the passage of calcium ions. The effects of calcium concentration on the core gelation are explored.     

The Properties of Powers: Didactic Contract and Gender Gap

International Journal of Science and Mathematics Education - National and international large-scale assessments of mathematics show that, in most nations, males achieve better results than females...     

Organizing links with science: Cooperate or contract?: A project-level analysis

Links with science have been argued to improve the (innovation) performance of firms. Yet we still know comparatively little about the project-level characteristics affecting the organization of such links. Our study, based on a sample of 52 projects carried out by a multinational company in the semiconductor industry, reveals that the knowledge attributes of a project help in predicting how the R&D activities will be organized. In particular, basic projects are likely to be developed through formal cooperative agreements with universities. Such projects also tend to be strategically less important. For strategically more important projects, in contrast, and for those where the knowledge to be developed is particularly novel to the firm, the firm is more likely to resort to formal contracting with a university for a specific component of the R&D project, usually early on in the project.     

Orthographic Neighborhood-Size Effects on the Reading Aloud of Italian Children With and Without Dyslexia

This study examines the effects of orthographic neighborhood size (N-size) in relationship with word frequency on the reading aloud of children with and without dyslexia whose language has a consistent orthography. Participants included 22 Italian fourth-grade children with dyslexia and 44 age-matched typically developing readers. Children with dyslexia read low-frequency words with high N-size faster than words that had no neighbors; by contrast, typically developing readers showed no N-size effects, irrespective of word frequency. The facilitating effect of N-size on low-frequency word reading in children with dyslexia indicates that they benefit from lexical activation spreading from dense neighborhoods.     

Validating the Conceptions of Assessment-III Scale in Canadian Preservice Teachers

Building on Snow's (1989) idea of 2 pathways to achievement outcomes, a performance and a commitment pathway, this study examined how cognitive and motivational factors associated with each of these pathways, respectively, contributed to the prediction of achievement outcomes in science. The sample consisted of 491 10th- and 11th-grade high school students. Results of hierarchical regression analyses showed that (a) students' cognitive abilities were the strongest predictors of their performance in science as measured by standardized test scores; (b) motivational processes enhanced the predictive validity for science test scores and grades beyond the variance accounted for by ability; and (c) motivational processes were the strongest predictors of students' commitment to science in the form of situational engagement and anticipated choices of science-related college majors and careers. These results are consistent with Snow's (1989) conjecture that both performance and commitment pathway-related factors are necessary for understanding the full range of person-level inputs to achievement outcomes.     

Whole body vibration: unsupervised training or combined with a supervised multi-purpose exercise for fitness?

Abstract

The aim of the study was to compare the effect of an unsupervised whole body vibration (WBV) training and two different supervised multi-purpose exercise programmes, with and without WBV, on body composition, functional fitness and self-reported well-being in middle-aged adults. Fifty-four healthy participants (age 48.6 ± 6.7 years) were randomly assigned to a vibration group (VG), a multi-purpose exercise group (MG) and a multi-purpose exercise with vibration group (VMG) and trained 3 days a week for 4 months. VG performed a standardised unsupervised WBV protocol, MG a supervised multi-purpose exercise and VMG a multi-purpose exercise including vibration. After training, drop out was significantly higher in VG group (P = 0.016) when compared to VMG group. In both MG and VMG, body composition, sit-up, push-up, sit and reach, agility test, hopping test and self-reported general health significantly improved (P < 0.05). No additive effects were generated by the vibration stimulus. Percentage of body fat and agility test in VG had a significant opposite trend compared to VMG group (P < 0.05). In summary, an unsupervised WBV training should not be chosen for training protocol. However, positive effects on physical fitness and the best results in adherence could be achieved integrating WBV practice into a multi-purpose exercise training.     

Listening text comprehension in preschoolers: a longitudinal study on the role of semantic components

A longitudinal study analyzed (a) which lower- and higher-level semantic components uniquely predicted listening text comprehension and (b) the nature of the relation (i.e., direct and indirect) between the predictors and listening text comprehension in preschoolers. One-hundred and fifty-two children participated in the present study (68 females; mean age = 4;10 years/months and 5;5 years/months at Time 1 and Time 2, respectively). Participants were administered measures to evaluate listening text comprehension (Time 1 and Time 2) and (a) expressive and receptive word knowledge (lower-level semantic components), and (b) inferential skills and the ability to use context (higher-level semantic components) (Time 1). Verbal short-term and working memory were also included as control variables. Data were analyzed using path analysis models. Results showed that both types of semantic components (a) accounted for unique variance in listening text comprehension at Time 2, with lower-level semantic components explaining a larger proportion of variance than higher-level semantic components; (b) were related to later listening text comprehension through direct and indirect relations. Memory resources did not significantly contribute to listening text comprehension. The results are discussed in light of their theoretical relevance and educational/practical implications.