Spontaneous Tumor Lysis Syndrome in an Infant: A Case Report

Tumor lysis syndrome has been observed in patients with malignancies with high cellular burden and high cell turnover, tumor sensitive to therapy, especially after initiating medical treatment. It very rarely occurs spontaneously. The case described here is of 6 months male infant who presented with fever since 1 month and loose stools associated with blood since 15 days. The laboratory investigations showed lactate dehydrogenase (LDH) of 6,192 IU/L and serum uric acid 18.2 mg/dl along with pancytopenia. The infant presented with electrolyte abnormalities and renal failure.     

Narrating Your Work: an approach to supporting knowledge sharing in virtual teams

We propose an approach to enhancing knowledge sharing and connectedness in distributed teams. Termed ‘Narrating Your Work’ (NYW), the approach involves members of distributed team using a microblogging tool to post regular updates about their current work, accomplishments, and issues. The NYW approach was evaluated within a geographically and temporally distributed team at Shell International for a period of one month, using a mixed-method research design. Methodology comprised of a quantitative survey, followed by semi-structured interviews and analysis of microblogging updates posted during the month in which the approach was being trialled. The evaluation results suggest that NYW was viewed as a valid and practical approach to enhancing knowledge sharing and connectedness. A range of barriers and enablers that could impact the future application and embedding of the approach are identified and recommendations for implementation are outlined.     

Wearable inertial sensors in swimming motion analysis: a systematic review

The use of contemporary technology is widely recognised as a key tool for enhancing competitive performance in swimming. Video analysis is traditionally used by coaches to acquire reliable biomechanical data about swimming performance; however, this approach requires a huge computational effort, thus introducing a delay in providing quantitative information. Inertial and magnetic sensors, including accelerometers, gyroscopes and magnetometers, have been recently introduced to assess the biomechanics of swimming performance. Research in this field has attracted a great deal of interest in the last decade due to the gradual improvement of the performance of sensors and the decreasing cost of miniaturised wearable devices. With the aim of describing the state of the art of current developments in this area, a systematic review of the existing methods was performed using the following databases: PubMed, ISI Web of Knowledge, IEEE Xplore, Google Scholar, Scopus and Science Direct. Twenty-seven articles published in indexed journals and conference proceedings, focusing on the biomechanical analysis of swimming by means of inertial sensors were reviewed. The articles were categorised according to sensor’s specification, anatomical sites where the sensors were attached, experimental design and applications for the analysis of swimming performance. Results indicate that inertial sensors are reliable tools for swimming biomechanical analyses.     

Effects of changing speed on knee and ankle joint load during walking and running

Joint moments can be used as an indicator of joint loading and have potential application for sports performance and injury prevention. The effects of changing walking and running speeds on joint moments for the different planes of motion still are debatable. Here, we compared knee and ankle moments during walking and running at different speeds. Data were collected from 11 recreational male runners to determine knee and ankle joint moments during different conditions. Conditions include walking at a comfortable speed (self-selected pacing), fast walking (fastest speed possible), slow running (speed corresponding to 30% slower than running) and running (at 4 m · s^?1 ± 10%). A different joint moment pattern was observed between walking and running. We observed a general increase in joint load for sagittal and frontal planes as speed increased, while the effects of speed were not clear in the transverse plane moments. Although differences tend to be more pronounced when gait changed from walking to running, the peak moments, in general, increased when speed increased from comfortable walking to fast walking and from slow running to running mainly in the sagittal and frontal planes. Knee flexion moment was higher in walking than in running due to larger knee extension. Results suggest caution when recommending walking over running in an attempt to reduce knee joint loading. The different effects of speed increments during walking and running should be considered with regard to the prevention of injuries and for rehabilitation purposes.     

巴西档案学的发展历程及其影响

文章首先介绍了巴西档案学课程在大学设立的历程,接着讨论了巴西档案学与情报学的关系,论述了知识信息时代巴西档案工作者培养计划面临的挑战和应对措施,最后,针对巴西档案学及巴西档案工作人才培养面临的挑战得出了几点结论.     

Medical library services in Switzerland: catching up with EBM

The feature is a part of the series about medical library services in various countries. It gives an overview of medical library services to support research, education and clinical practice in Switzerland. Data were collected by means of an online survey and set in the wider context of the Swiss healthcare system. Key findings are that library services, including support by academic librarians, are provided to health care staff in hospitals – both university and others, while there is no information service infrastructure to serve the large number of GPs and specialists who mostly run their own practice. The authors recommend that – if the health authorities take EBM seriously – information services should be introduced for these small practices. J.M.     

Phonological Processing and Word Reading in Typically Developing and Reading Disabled Children: Severity Matters

In this study word reading (WR) fluency was used to dichotomously classify 1,598 Dutch children at different cutoffs, indicating (very) poor or (very) good reading performance. Analysis of variance and receiver operating characteristics were used to investigate the effects of rapid automatized naming (RAN) and phonemic awareness (PA) in predicting group membership. The highest predictive values were found for the combination of RAN and PA, particularly for the poorest readers. Furthermore, results indicate that with the severity of impairment, WR is more dominated by deficient PA, which is interpreted as an enduring problem with sublexical processing. Another main result is that with the increase of reading skill, the contribution of PA diminishes, whereas the contribution of RAN remains fairly constant for the whole reading fluency continuum. These results warrant the conclusion that whereas PA hallmarks reading disability, RAN appears to be the default predictor for above-average or excellent reading proficiency.