Convergent genomic signatures of high-altitude adaptation among domestic mammals

Abundant and diverse domestic mammals living on the Tibetan Plateau provide useful materials for investigating adaptive evolution and genetic convergence. Here, we used 327 genomes from horses, sheep, goats, cattle, pigs and dogs living at both high and low altitudes, including 73 genomes generated for this study, to disentangle the genetic mechanisms underlying local adaptation of domestic mammals. Although molecular convergence is comparatively rare at the DNA sequence level, we found convergent signature of positive selection at the gene level, particularly the EPAS1 gene in these Tibetan domestic mammals. We also reported a potential function in response to hypoxia for the gene C10orf67, which underwent positive selection in three of the domestic mammals. Our data provide an insight into adaptive evolution of high-altitude domestic mammals, and should facilitate the search for additional novel genes involved in the hypoxia response pathway.     

要遏制机遇因素在干部任用中的作用

机遇因素长期困扰我国人事任用工作。遏制干部任用中的机遇因素,主要应从坚持党管干部工作原则、改革人事制度、加强政治教育工作、加大人事工作反腐倡廉力度等方面作好工作,为建设一支高素质的干部队伍,提供组织保证、人才保证。     

关于破损档案揭粘技术

关于破损档案揭粘技术一、档案粘结原因及类型档案保存多年后,在多种因素影响下,有部分档案的纸张发生粘连。严重的粘结成块,像砖头一样结实,很难分离,人们常称之为“档案砖”。产生以上现象的原因极其复杂,主要是档案材料、环境、生物、人为等因素的综合作用。成因...     

Distributed event-triggered adaptive finite-time consensus control for second-order multi-agent systems with connectivity preservation

In this paper, we consider the robust finite-time consensus problem for second-order multi-agent systems (MASs) with limited sensing range and weak communication ability. As a stepping stone, a novel distributed finite-time sliding mode manifold is developed for MASs. Then, by combining artificial potential function technique with the presented sliding mode manifold, a robust distributed control scheme is proposed to enable the finite-time consensus of MASs while preserving the prescribed communication connectivity. Furthermore, the sampling frequency and implementation burden of the proposed controller can be reduced with resort to the event-triggered methodology. Finally, numerical examples are given to show the effectiveness of the proposed method.     

信息综合管理系统控制平台的构建

阐述了平台系统的基本组成；论述了平台系统核心技术的数学抽象；提出了LB(Line Basic)语言及面向平台的程序设计思想；介绍了平台语言的设计原理；描述了LB语言的通用指令集；给出了平台系统的五种权限管理策略；通过指令效率分析优化了平台系统，从而通过LB语言将显示模式及众多的内部函数组成一个有机的整体，使平台系统成为集开发与应用为一体的大型软件系统。     

提升陕西民办高等教育办学水平和综合实力的若干思考

文章对陕西民办高等教育目前存在的问题进行了深入分析,并从培养目标、培养方案、培养体系、培养条件、市场导向的角度提出了提升陕西民办高等教育办学水平和综合实力的对策思考。     

我国自行车运动科学训练理论与训练监控研究现状

自行车是典型的体能性运动项目,专项体能水平是决定比赛成绩的重要因素,心理、战术、技术等对于竞技水平的发挥有着重要影响作用,自行车运动员科学训练是取得优异成绩的保障。对我国自行车运动科学训练理论发展及训练监控的研究现状进行综述,对科学训练中的一些热点问题和主要研究成果进行评述,并对以后发展方向提出了展望,以期对我国自行车运动研究与实践提供参考。     

基于英语学科核心素养的中学英语"以读促写"教学的思考

英语学科核心素养有语言能力、文化意识、思维品质和学习能力四大要素.阅读板块是英语学科核心素养落地的重要阵地,写作板块是学生语言学习的重难点,阅读与写作是紧密相连、相互融合的整体.如何将核心素养具体落实在英语阅读和写作教学中,用"以读促写"的方式同时提升学生的阅读与写作能力是本文探讨的焦点.本文提出了"以读促写"教学设计的三个步骤,即:分析篇章信息、结构、语言和文章内涵,找出阅读中可以借鉴到写作中的点,在写作中迁移和运用.     

青藏铁路冲刷防护补强设计工程施工技术

本文主要介绍了青藏铁路冲刷防护补强设计工程施工技术的实施情况，为以后施工该类型情况时提供了不可多得的经验。     

Photoinduced Electron Transfer, Energy Transfer and Chemical Reactions in Supramolecular Systems

This project is devoted to the interdisciplinary studies of organic and physical chemistry, and involves three parts: