Entrepreneurialism at the University of Zagreb: Managing the Sustainability of Change

This article presents a study of the different aspects of entrepreneurialism at the University of Zagreb in the context of Croatian higher education. The recent history of changes at the University of Zagreb is described using a temporal perspective from the beginning of the development of the European Higher Education Area to the implementation of the Bologna Process in Croatia. The theoretical framework for the study has been Burton Clark's (1998 Clark, B. R. 1998. Creating Entrepreneurial Universities, Oxford: Pergamont and Elsevier Science. Organizational Pathways of Transformation [Google Scholar]) seminal analysis of the main features of academic entrepreneurialism. Each feature: the strengthening of steering capacity, the diversification of financial sources, a stimulated academic heartland, an extended periphery, and integrating entrepreneurial culture have been elaborated using the illustrative examples from university practice and university statistics. The last part of the study gives an overview of the results of the empirical study conducted among university managers, teachers, and students on their perceptions of the university's entrepreneurial culture at the level of the institution as a whole as well as at the level of their respective faculty. In the final conclusions, the main requirements for effective change management within the university context are listed.     

An architectural assessment method for new exterior additions to historic buildings

The design approaches of new exterior additions to historic buildings have been among the ongoing debates in the field of architectural conservation. The aim of this study is to develop an assessment method, which can be used to determine the compatibility in architectural expression of the new addition in relation to the characteristics of a historic building. This method is based on the architectural analysis, which includes environmental relations, building-lot relations, mass relations and the facade composition of the historic building both before and after the new addition in relation to the value of a historical building. In this study, a selected group of historic buildings in ?zmir, Turkey with new exterior additions was analysed with regard to their exterior architectural characteristics in order to evaluate the compatibility of the new addition, by employing the use of contemporary conservation principles. The importance of this study is to guide architects to form the basis of a decision for developing an integrated approach in designing new additions in the course of the actual design process. On the other hand, the proposed method can be evaluated as a contribution to the emerging field of heritage impact assessments as well as scientific assistance to local governments to criticize specific projects of cultural heritage assets submitted for appraisal. Analysis results showed that the value of the historic building should first clearly be identified and a new addition should bear the identity of its own period. However, instead of altering the scale or form of the historic building, a new addition should complement and contribute to the sense of proportion, disposition and historical pattern.     

Macroprolactinemia: new insights in hyperprolactinemia

Hypersecretion of prolactin by lactotroph cells of the anterior pituitary may lead to hyperprolactinemia in physiological, pathological and idiopathic conditions. Most patients with idiopathic hyperprolactinemia may have radiologically undetected microprolactinomas, but some may present other causes of hyperprolactinemia described as macroprolactinemia. This condition corresponds to the predominance of higher molecular mass prolactin forms (big-big prolactin, MW > 150 kDa), that have been postulated to represent prolactin monomer complexed with anti-prolactin immunoglobulins or autoantibodies. The prevalence of macroprolactinemia in hyperprolactinemic populations between 15-46% has been reported. In the pathophysiology of macroprolactinemia it seems that pituitary prolactin has antigenicity, leading to the production of anti-prolactin autoantibodies, and these antibodies reduce prolactin bioactivity and delay prolactin clearance. Antibody-bound prolactin is big enough to be confined to vascular spaces, and therefore macroprolactinemia develops due to the delayed clearance of prolactin rather than increased production. Although the clinical symptoms are less frequent in macroprolactinemic patients, they could not be differentiated from true hyperprolactinemic patients, on the basis of clinical features alone. Although gel filtration chromatography (GFC) is known to be the gold standard for detecting macroprolactin, the polyethylene glycol precipitation (PEG) method has offered a simple, cheap, and highly suitable alternative. In conclusion, macroprolactinemia can be considered a benign condition with low incidence of clinical symptoms and therefore hormonal and imaging investigations as well as medical or surgical treatment and prolonged follow-up are not necessary.     

Approximation based on orthogonal and almost orthogonal functions

In this paper, we define a class of almost orthogonal rational functions of Legendre type in a new manner. Relations of these functions with classical exponentional functions orthogonal over interval (0, ∞), as well as classical polynomials orthogonal over (0, 1) are explained. Defining relations of these functions can be used for designing almost orthogonal filters. These filters are generators of orthogonal signals and can be successfully applied in finding the best signal approximation in the sense of the mean square error. The filters orthogonal property enables building of physical (in this case electrical) models of dynamical systems (the sources of signals to be approximated) either with less components for the same model accuracy or higher accuracy for the same number of components than the other known models. New filters represent further improvement of previously designed filters, by the same authors, in the sense of simplicity, higher accuracy, lesser approximation time and even a possibility to approximate signals generated by systems with built-in imperfections. Series of experiments were performed to analyze the dependence of approximation accuracy and the number of filters sections.     

Understandings of current environmental issues: Turkish case study in six teacher education colleges

The purpose of this study is to profile future science teachers’ understandings of current environmental issues in the context of an education reform in Turkey. Knowledge base and understandings of elementary and secondary prospective science teachers about biodiversity, carbon cycle, global warming and ozone layer depletion were targeted in the study. Questionnaire surveys developed for this purpose were adapted and used in this investigation. The questionnaires were administered to 360 participants in six universities. Analysis involved frequencies, percentages and comparing means for students majoring in elementary and secondary science teaching. Analysis of variance for differences among majors and responses to different issues are also included. Findings are compared and contrasted with the previous research in other countries. The study has implications for the prospective preparation of teachers and the future of environmental literacy movement in Turkey.     

Learning habits of students with special needs in short‐term vocational education programmes

This research examined some characteristics of the learning habits of students with special needs and those without them in programmes of short‐term vocational education in five areas: motivation, learning and learning techniques, emotional, social and the area of self‐evaluation. The research sample consisted of 140 students from different secondary schools. The Questionnaire on the Learning Habits of Adolescents was used for the purpose of the study. The differences between the means from individual learning habit scales, between the students with special needs or without them, were discovered by one‐way analysis of variance. Basic findings of empirical research emphasise that there exist statistically significant differences between the students with special needs and the students without special needs in four areas of learning habits. Among the findings causing concern in connection with learning habits, we would like to underscore the fact that students with special needs are perceived as less efficient at and less competent in coping with learning and work tasks. These students are not familiar with effective methods and strategies for successful learning, which leads to the feelings of frustration and helplessness in case of failure. In order to cultivate an effective and supportive educational environment for students with special needs, short‐term vocational schools should develop learning/teaching models that provide a potentially powerful alternative to traditionally directed teaching approaches.     

The missing slope: paradoxical shortening of activated partial thromboplastin time in a patient on unfractionated heparin therapy

This case report describes false shortening of activated partial thromboplastin time (aPTT) due to erroneous optical reading of the clotting point in the presence of unfractionated heparin (UFH), and a biphasic waveform. Activated partial thromboplastin time performed on a coagulometer with photo-optical detection yielded an ambiguous clotting curve characterized by an early and steady decrease in light transmittance throughout the whole measuring range, with the clotting point read at 65 seconds. Further investigations included measurement of aPTT by means of a mechanical clot detection method as well as determination of another heparin-sensitive coagulation assay, that is thrombin time (TT), both being unmeasurably prolonged (> 150 seconds). Communication with clinicians revealed that the patient was on continuous UFH therapy and had an underlying sepsis, with highly elevated C-reactive protein (289 mg/L). The aPTT measurements requested at three timepoints later during the same day revealed gradual aPTT shortening and unveiled a peculiar biphasic waveform pattern. In this case, unmeasurably prolonged aPTT due to UFH therapy was masked by a biphasic aPTT curve pattern making only the first slope of the biphasic waveform visible within the measuring range. The early decrease in plasma light transmittance mimicked optical changes related to clot formation, thus causing erroneous optical reading and yielding a falsely shortened aPTT. This case emphasizes that such a pattern should be carefully inspected, especially when a combination of a critically ill condition and UFH therapy is present, in order to prevent erroneous reporting of aPTT and potential adverse effects on patient care.     

The effect of inspiratory muscle fatigue on acid-base status and performance during race-paced middle-distance swimming

The aim of this study was to investigate the effect of pre-induced inspiratory muscle fatigue (IMF) on race-paced swimming and acid-base status. Twenty-one collegiate swimmers performed two discontinuous 400-m race-paced swims on separate days, with (IMF trial) and without (control trial) pre-induced IMF. Swimming characteristics, inspiratory and expiratory mouth pressures, and blood parameters were recorded. IMF and expiratory muscle fatigue (P < 0.05) were evident after both trials and swimming time was slower (P < 0.05) from 150-m following IMF inducement. Pre-induced IMF increased pH before the swim (P < 0.01) and reduced bicarbonate (P < 0.05) and the pressure of carbon dioxide (PCO₂) (P < 0.05). pH (P < 0.05), bicarbonate (P < 0.01) and PCO₂ (P < 0.05) were lower during swimming in the IMF trial. Blood lactate was similar before both trials (P > 0.05) but was higher (P < 0.01) in the IMF trial after swimming. Pre-induced IMF induced respiratory alkalosis, reduced bicarbonate buffering capacity and slowed swimming speed. Pre-induced and propulsion-induced IMF reflected metabolic acidosis arising from dual role breathing and propulsion muscle fatigue.