Neurosurgical treatment for addiction: lessons from an untold story in China and a path forward

Addiction is a major public-health crisis associated with significant disability and mortality. Although various pharmacological and behavioral treatments are currently available, the clinical efficacy of these treatments is limited. Given this situation, there is a growing interest in finding an effective neurosurgical treatment for addiction. First, we discuss the use of ablative surgery in treating addiction. We focus on the rise and fall of nucleus accumbens ablation for addiction in China. Subsequently, we review recent studies that have explored the efficacy and safety of deep-brain-stimulation treatment for addiction. We conclude that neurosurgical procedures, particularly deep-brain stimulation, have a potentially valuable role in the management of otherwise intractable addictive disorders. Larger well-controlled clinical trials, however, are needed to assess clinical efficacy and safety. We end by discussing several key issues involved in this clinical field and identifying some areas of progress.     

State-dependent retention induced by postacquisition exposure to pentobarbital or shock stress in rats

Although state-dependent retention (SDR) has been the focus of considerable research in recent years, there has been little work demonstrating this phenomenon when the treatment is administeredafter learning. In the present study, the effectiveness of two different treatments, pentobarbital and shock-induced stress, in producing postacquisition SDR in rats was examined. In all experiments, water-deprived rats were exposed to a novel flavor, apple juice, on each of 2 days. Subjects that remember their initial exposure to this substance should show an increase in consumption on their second exposure (i.e., an attenuation of neophobia). It was found that subjects exposed to pentobarbital (Experiment 1) or shock-induced stress (Experiment 2) immediately after their initial exposure did not increase their intake on the subsequent exposure unless they were reexposed to pentobarbital (Experiment 1) or shock-induced stress (Experiment 2b) shortly prior to that exposure. These results clearly show that this “attenuation of neophobia” paradigm can be used to investigate postacquisition SDR.     

The Multiple Subfunctions of Attention: Differential Developmental Gateways to Literacy and Numeracy

Attention is construed as multicomponential, but the roles of its distinct subfunctions in shaping the broader developing cognitive landscape are poorly understood. The current study assessed 3‐ to 6‐year‐olds (N = 83) to: (a) trace developmental trajectories of attentional processes and their structure in early childhood and (b) measure the impact of distinct attention subfunctions on concurrent and longitudinal abilities related to literacy and numeracy. Distinct trajectories across attention measures revealed the emergence of 2 attentional factors, encompassing “executive” and “sustained–selective” processes. Executive attention predicted concurrent abilities across domains at Time 1, whereas sustained–selective attention predicted basic numeracy 1 year later. These concurrent and longitudinal constraints cast a broader light on the unfolding relations between domain‐general and domain‐specific processes over early childhood.     

The role of scientific positivism in European popular educational movements: the case of France

Scientific positivism was one of the most influential ideologies of progress in the early modern period and had a powerful impact on the formation of popular educational movements in the 19th century in Europe. This paper considers the form it took in France, probably the most sophisticated example, which itself influenced other European movements. It traces, briefly, the rise of positivism from Bacon through the Scottish Enlightenment philosophers to Auguste Comte and then considers how this movement found an educational vehicle in, firstly, the French Grand-Orient organization of freemasonry and then through the universités populaires. It is argued that the strength of the movement was in its resistance to authoritarian epistemologies, in particular clericalism, and in its commitment to learning based on individual experience and experimentation. In France, it becomes adopted by the Radical Party, led by Jules Ferry, as an official ideology for reforming education having first been widely diffused through Masonic educational organizations. It informs a ‘third way’ politics opposed both to laissez faire capitalism and revolutionary Marxism offering an apparently ‘scientific’ neutrality. The study demonstrates the importance of freemasonry as a vehicle for popular educational movements in the 19th century and the notions of class harmony it promoted, which underpinned the foundations of the newly emerging welfare state.     

Oldham’s Moot (1938–1947), the universities and the adult citizen

The influential policy work in education of the intellectual grouping formed by J.H. Oldham during the Second World War known as ‘Oldham’s Moot’ (1938–1947) has been discussed in recent publications. These have noted its general educational and university policy, its intellectual strengths, and the role of Sir Walter Moberly in relation to his chairmanship of the UGC and his The Crisis in the University (1949). Others have placed its thinking in a tradition of Christian medievalism and British intellectual movements. This article focuses on the social theories debated in the group, especially their European roots, their contribution to their discussions on the university and especially the role of adult citizenship in the era of ‘Planning of Freedom’. In particular the authors follow the arguments concerning the integration of adult education in the university reform they envisage.     

Short-term memory for haptic cues in monkeys (Macaca mulatta)

Short-term memory (STM) for haptic information was examined in a delayed matching-to-sample (DMTS) task. Three rhesus monkeys were tested in DMTS with all possible combinations of different-size spheres and cubes as the sample and comparison stimuli. The results showed that the decrease in percentage correct as a function of the retention intervals was relatively independent of the size and shape of the sample and comparison stimuli. In general, at each retention interval, percentage correct was higher when the (1) comparison stimuli differed in both size and shape than when the comparison stimuli differed in only size or shape, (2) size differences between the comparison stimuli increased, and (3) samples were spheres rather than cubes. This pattern of results suggests that dimensions of the haptic stimuli influenced discrimination but had little effect on the animals’ STM. In Experiment 2, the same three monkeys responded to the sample and comparison stimuli with the same hand or responded to the sample with one hand and the comparison stimuli with the opposite hand. The decrease in percentage correct across retention intervals was comparable for all possible hand combinations. These results suggest that the loss of information from STM is comparable when the sample and comparison stimuli are both felt with the same hand or with opposite hands.     

Writing groups as transformative spaces

Curriculum transformation is a central concern for higher education in response to rapidly expanding technologies, globalisation and the widening diversity of the student and staff body. This is particularly true for South Africa, which is still grappling with inequalities and pressure for social redress in its universities. Early responses to supporting students took the form of add-on, ‘deficit-model’ approaches which understood poor student retention and success rates as emerging from students’ lack of neutral literacy ‘skills’. Recent initiatives have begun to adopt more socio-cultural understandings of literacy that seek to challenge traditional power structures and cultivate horizontal peer-orientated spaces for learning with a focus on practice rather than on product. Writing groups, as spaces for academic writing development, embrace this orientation and are argued to provide a transformative framework that foregrounds proactive student learning and experience, while still accommodating disciplinary learning through peer engagement. Drawing on the successful implementation of such forms of support at a research-intensive university, this paper argues that writing groups can play a critical role in both personal (student) transformation and broader curriculum transformation. Data include anonymous questionnaires and surveys with participants and coordinators of the writing groups. An inductive, constant comparative analysis indicated that students feel empowered in this space to develop not only their writing practices but also their transforming identities as scholars. Writing groups were found to provide ‘safe spaces’ where academic practices can be made explicit and where they can be challenged. The paper therefore argues that writing groups can play a small but key role in broader transformation efforts.     

Happiness,pride and elite sporting success: What population segments gain most from national athletic achievements?

Elite sports are widely considered by national governments as a merit good through which many benefits to society as whole can be fostered through the stimulation of ‘national pride’ and ‘happiness’ (or ‘wellbeing’). The aim of this paper is to analyze what factors influence perceived national pride and happiness when athletes succeed at major national and/or international competitions. Based on a nation-wide survey, data was collected from n = 2006 randomly selected Germans by means of a computer assisted telephone interview. The results reveal that 66.2% respondents felt proud and 65.6% respondents were happy when German athletes were successful at major events. National pride and happiness were significantly explained through interest in elite sports, sport participation and socio-economic variables. The results reveal that there are differences between the perception of pride and that of happiness. Women, individuals with a low educational background, and low income and individuals having a migration background are the population segments who gain most from the sporting success of elite athletes. The results show in particular that the funding of elite sports and elite athletes can be considered as policy tool for social integration.