Combined training,FNDC5/irisin levels and metabolic markers in obese men: A randomised controlled trial

The effects of training on FNDC5/irisin and its association with fitness and metabolic marker improvements induced by training have been poorly investigated in humans. Thus, the present study assessed the effects of combined training (CT) on FNDC5/irisin levels, metabolic markers and fitness adaptations in obese men. Middle-age obese men (age 49.13?±?5.75, body mass index (BMI) 30.86?±?1.63) were randomly distributed in the CT group (n?=?12) and control group (CG n?=?10). The CT consisted of strength followed by aerobic training, 3 times/week, for 24 weeks. Body composition, physical fitness, plasma FNDC5/irisin, biochemical markers and metabolic scores/index were evaluated. CT maintained FNDC5/irisin levels (µg/mL) (pre: 4.15?±?0.32, post: 4.21?±?0.32; p?=?.96) and improved body composition, metabolic and physical fitness markers. In the CG, decreased FNDC5/irisin (µg/mL) (pre: 4.36?±?0.23, post: 3.57?±?0.94; p?=?.01) and reduced strength (supine exercise/kg) (pre: 71?±?14.7, post: 60.1?±?14.05; p?<?.01) were observed, along with a trend to increase HOMA-IR (pre: 2.63?±?1.11, post: 3.14?±?1.27; p?=?.07) and other indicators of metabolic deterioration. An inverse correlation was found between the change (Δ%) in levels of FNDC5/irisin and Δ% glucose, Δ% total cholesterol, Δ% triglycerides and Δ% waist circumference, in addition to a positive relation with Δ% muscle strength. In conclusion, CT maintained FNDC5/irisin levels and provided metabolic and fitness benefits. The correlation between FNDC5/irisin changes and metabolic parameters, as well as the FNDC5/irisin reduction associated with fitness and metabolic worsening in the CG, suggests a relationship between FNDC5/irisin and a healthy metabolic status in humans.     

Challenging Educational Assumptions: Lessons from an Italian-American collaboration

In this paper, the authors argue that in order to create a curriculum of the future, we need to re-evaluate at least four key assumptions about teaching and learning that have guided educational decisions in the past. These assumptions are: learning is the result of individual, rather than group, activity; teachers are consumers, rather than generators, of theory; assessment is concerned with evaluating learning outcomes, rather than learning processes; teaching and learning are primarily cognitive, rather than aesthetic, ethical or affective, acts. Drawing on recent cross-cultural research, the authors use the example of the municipal pre-schools and infant-toddler centres of Reggio Emilia, Italy, to challenge these assumptions and suggest alternative ways for imagining classrooms of the future.     

Substantiating the need to apply a sociocultural lens to the preparation of teachers in an effort to achieve science reform

This qualitative, sociocultural study examines how teacher preparation programs may have deliberate impact on science reform by unearthing the complex layers of diversity inherent in the contextual reality of education. This study was conducted in one of the largest school districts in the Southeastern United States, serving a predominately Hispanic population comprising 65 % of its student body, followed by African Americans at 24 %. The representative subjects utilized for this study were elementary education undergraduate students and later a percentage of the same subjects, as practicing teachers in the field. All subjects were exposed to inquiry based methodology in science teaching as part of their undergraduate studies with emphasis on the learning cycle, facilitation of student voice and exposure to the nature of science. The goal of science education was emphasized to students as purposeful in promoting scientific literacy. This study is framed by sociocultural theory grounded in a social constructivist paradigm with the understanding that science learning takes place within social and collaborative processes leading to internalization and greater sense of self-efficacy. The study examines the perception of education students’ beliefs about scientists as well as reflections on their own learning of science as elementary students themselves. As present practicing teachers, perspectives from their position in the field were obtained via interviews. Interviews served to elicit reflections on present practice as related to previous perceptions, in order to analyze whether these were pervasive in framing practice as well as self-perceptions related to science. A lack of change of these perceptions may underscore the importance of an emphasis on issues of gender, culture and social factors within teacher preparation, specific to science teaching and learning. Cognizance of such factors are believed to support internalization and hence greater understanding of the complexities framing science teaching and learning, leading to an actual paradigm shift in our elementary science classrooms.     

Characteristics of Swedish preschools that provide education and care to children with special educational needs

In Sweden, preschool inclusion is embraced and preschools are open for children both with and without special educational needs. The purpose of this study was to examine the characteristics of a number of preschool units in Sweden that provide education and care to children with special educational needs with regard to organisation, resources and quality. The purpose was also to provide reflections on the usefulness of different structured observation rating scales designed to assess preschool quality. Eight preschool units located in four Swedish districts were visited. A total of sixteen 5-year-old children with special educational needs/disability and forty typically developing children of the same age participated. The data sources were structured observation rating scales (Early Childhood Environment Rating Scale, Caregiver Interaction Scale and Inclusive Classroom Profile), ABILITIES Index questionnaire, unstructured observation, interviews, conversations and documents. Two overall typologies of preschool units were identified: the comprehensive units enrolled children with various special educational needs/disability, while the specialised units enrolled children with the same disability. The staff resources were greater in the specialised units. The overall quality in the observed units ranged from low to good. In units educating children with a disability diagnosis, the quality was never low. None of the preschool units was scored as having a good inclusive environment. The structured observation rating scales complemented each other and covered, in part, different quality aspects of the units. The study shows that there is a large variation in quality between the units and that there is a need to further develop the quality of the preschool units and of the services for children with special educational needs in Swedish preschools.     

Linkages Between Children's and Their Friends' Social and Physical Aggression: Evidence for a Gene–Environment Interaction?

Based on a sample of 406 seven-year-old twins, this study examined whether exposure to friends' social or physical aggression, respectively, moderates the effect of heritability on children's own social and physical aggression. Univariate analyses showed that children's own social and physical aggression were significantly explained by genetic factors, whereas friends' social and physical aggression represented "true" environmental factors that were unrelated to children's genetic dispositions. Multivariate analyses further suggested a possible gene–environment interaction in the link between friends' and children's physical aggression but not in the link between friends' and children's social aggression. Instead, friends' social aggression was directly related to children's social aggression, in addition to genetic effects on this behavior. Theoretical and practical implications of these results are discussed.