Metabolic time-course response after resistance exercise: A metabolomics approach

This study analysed the time course of the global metabolic acute response after resistance exercise (RE), with the use of proton nuclear magnetic resonance (¹H NMR) spectroscopy. Ten young healthy males performed 4 sets of 10 repetitions at 70% of one-repetition maximum in the leg press and knee extension exercises and had the serum metabolome assessed at 5, 15, 30 and 60 min post-RE. Measurements were also performed 1 h earlier and immediately before the exercises, as an attempt to characterise each participant’s serum metabolome at rest. One-way ANOVA was applied and the significance level was set at P ≤ 0.05. RE promoted an increase in 2-hydroxybutyrate, 2-oxoisocaproate, 3-hydroxyisobutyrate, alanine, hypoxanthine, lactate, pyruvate and succinate concentrations. However, isoleucine, leucine, lysine, ornithine and valine had their concentrations decreased post-RE compared with at rest. This is the first study to show significant changes in serum concentration of metabolites such as 2-oxoisocaproate, 2-hydroxybutyrate, 3-hydroxyisobutyrate, lysine, hypoxanthine and pyruvate post-RE, attesting metabolomics as an interesting approach to advance in the understanding of global RE-induced metabolic changes. Moreover, the present data could influence the time point of blood collection in the future studies that aims to investigate metabolism and exercise.     

Tournament structure and nations' success in women's professional tennis

The relationship between domestic professional tournament structure in women's tennis and the subsequent professional ranking success of a nation's female players is examined. The 2003 women's professional tennis tournament calendar provided the distribution of events in 33 countries. Criteria used to classify nations' success in women's professional tennis were as follows: number of players with Women's Tennis Association (WTA) points, number of players with Top 200 rankings, and the combined WTA ranking of a nation's Top 5 female players. Pearson product - moment correlations were performed between the number of tournaments and the three criteria. Considerable variation was observed in the number of events organized between nations (USA, n = 56; Thailand, n = 3). All countries had internationally ranked female players, and 24 nations had players ranked in the Top 200. Results revealed relationships between a nation's number of women's professional events and both that nation's number of professionally ranked players (r = 0.60; P < 0.01) and Top 200 players (r = 0.60; P < 0.01), as well as the combined ranking of their Top 5 players (r = -0.52; P < 0.01). While a similar association was found between the number of professional events and players ranked in the men's game, there was no significant correlation between events held and the combined standing of nations' best five ranked players. Governing bodies and national associations in tennis should consider the provision of professional, domestic competition as key to the development of female tennis players.     

Deaf children's informal knowledge of multiplicative reasoning

Multiplicative reasoning is required in different contexts in mathematics: it is necessary to understand the concept of multipart units, involved in learning place value and measurement, and also to solve multiplication and division problems. Measures of hearing children's multiplicative reasoning at school entry are reliable and specific predictors of their mathematics achievement in school. An analysis of deaf children's informal multiplicative reasoning showed that deaf children under-perform in comparison to the hearing cohorts in their first two years of school. However, a brief training study, which significantly improved their success on these problems, suggested that this may be a performance, rather than a competence difference. Thus, it is possible and desirable to promote deaf children's multiplicative reasoning when they start school so that they are provided with a more solid basis for learning mathematics.     

Using the onto-semiotic approach to identify and analyze mathematical meaning when transiting between different coordinate systems in a multivariate context

The main objective of this paper is to apply the onto-semiotic approach to analyze the mathematical concept of different coordinate systems, as well as some situations and university students’ actions related to these coordinate systems. The identification of objects that emerge from the mathematical activity and a first intent to describe an epistemic network that relates to this activity were carried out. Multivariate calculus students’ responses to questions involving single and multivariate functions in polar, cylindrical, and spherical coordinates were used to classify semiotic functions that relate the different mathematical objects.     

Is there life beyond neoliberalism? Critical socio-educational alternatives for civic construction

How far does the neoliberal system pervade social and educational fields in its attempt to colonise the world of life? Neoliberalism is increasingly penetrating every aspect of human existence. From this context, this paper presents a set of alternative socio-educational experiences which are subtly constructing new latent revolutionary subjectivities. Critical educators, as transformative intellectuals, should use this crisis as an opportunity to social transformation by joining theory and praxis. Many people are now building ways of dialogic learning, new social relationships, commitment and collaborative ventures. This makes citizens more aware and critical, proving them with experiences of empowerment and cooperative work.     

Identification of histological threshold concepts in health sciences curricula: Students' perception

Students' metacognitive skills and perceptions are considered important variables for high-quality learning. In this study, students' perceptions were used to identify histological threshold concepts (integrative, irreversible, transformative, and troublesome) in three health sciences curricula. A specific questionnaire was developed and validated to characterize students' perceptions of histological threshold concepts. A sample of 410 undergraduate students enrolled in the dentistry, medicine, and pharmacy degree programs participated in the study. Concepts assessed in the study were clustered to ten categories (factors) by exploratory and confirmatory factor analysis. Concepts linked to tissue organization and tissue functional states received the highest scores from students in all degree programs, suggesting that the process of learning histology requires the integration of both static concepts related to the constituent elements of tissues and dynamic concepts such as stem cells as a tissue renewal substrate, or the euplasic, proplasic and retroplasic states of tissues. The complexity of integrating static and dynamic concepts may pose a challenging barrier to the comprehension of histology. In addition, several differences were detected among the students in different degree programs. Dentistry students more often perceived morphostructural concepts as threshold concepts, whereas medical students highlighted concepts related to two-dimensional microscopic identification. Lastly, pharmacy students identified concepts related to tissue general activity as critical for the comprehension and learning of histology. The identification of threshold concepts through students' perceptions is potentially useful to improve the teaching and learning process in health sciences curricula.     

Examining expansion and trends in higher education in Mozambique,Africa

Higher Education - Concerns about expansion in higher education (HE) have increasingly become a focus of educational policymakers in sub-Saharan countries. However, critical analysis and discussion...