The marginal costs of instruction

This is a study of the costs of instruction in a large public research university. It departs from other work on instructional costs in its attempt to draw inferences about the economic costs of incremental or marginal enrollments. Focusing on graduate education, we examine how the costs directly facing faculty differ from those incurred by the institution's administration and legislature as reflected in the budgetary rewards for instruction. These cost differences provide the wherewithal for a university to carry out basic research and other important functions that lack a paying clientele. The study also explores the roles of economic costs in the institution's pricing of graduate education.     

Sex differences and sex bias on the Boehm test of basic concepts: Do they exist?

Form A of the Boehm Test of Basic Concepts (BTBC) was administered to 180 kindergartners—90 boys and 90 girls. Neither their mean scores nor their standard deviations differed significantly, and the distributions of scores for the two groups were virtually identical. Moreover, the application of three internal criteria for bias yielded totally negative results; thus, there was no evidence of either sex differences or sex bias in the data.     

A symposium on “speech act theory in mainstream communication research”: An introduction

The referential, sequential, and inferential dimensions of discourse are explicated and discussed in order to obtain a vantage point from which to view the contributions of speech‐act theory to our understanding of human communication processes. A preview is then provided of four papers, each of which explores the intersection of two or more of these dimensions in order to enrich our understanding of speech‐act theory.     

Detection of enzymes dehydrogenases and proteases inBrugia malayi filarial parasites

Lymphatic filariasis caused mainly by infection fromW. bancrofti andB. malayi remains a major cause of clinical morbidity in tropical and subtropical countries. Analysis ofB. malayi mf, infective larval and adult worm lysates for the activity of enzymes led to the demonstration of activities of three key enzymes of carbohydrate metabolism viz., Malate dehydrogenase (MDH), Malic enzyme (ME) and Glucose-6-phosphate dehydrogenase (G6PDH) in all the three stages of the parasite. The specific activity of all the three dehydrogenases was significantly high in mf lysate compared to their activity in lysates of the other two stages (P<0.001). Analysis by native polyacrylamide gel to their activity inlysates of the other two stages (P<0.001). Analysis by native polyacrylamide gel electrophoresis (PAGE) using 7.5% non-gradient gel showed the presence of two isoforms of each of the three enzymes (MDH, ME & G6PDH) in mf lysate, while only one form of each enzyme was present in L₃ larval and adult worm lysates. Further proteolytic enzyme activity was demonstrated both in microfilarial and infective larval lysates ofB. malayi. While both mf and L₃ larval lysates showed optimal protease activity at alkaline pH of 9.0, the mf lysate showed increased activity also at pH 3.0. The infective larval lysate was markedly inhibited by Tosylamide-L-Phenylalanine chloromethyl ketone (TPCK), a thiol protease inhibitor, while the protease activity in mf lysate was significantly inhibited by both TPCK and a serine protease inhibitor Phenyl Methyl Sulphonyl Flouride (PMSF). In sodium do-decyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE), using gelatin copolymerized gel, the microfilarial lysate showed 3 protease molecules of 40 kDa, 180 kDa and 200 kDa and the L₃ larval lysate had 6 protease molecules of 18, 25, 37, 49, 70 and 200 kDa size.