我国“泛基础教育”制度剖析

我国现行的基础教育是一种横跨义务教育与非义务教育,纵跨学前教育、初等教育与中等教育的"泛基础教育".由于缺乏必要的基础性制度作为保障,"泛基础教育"存在许多制度壁垒,使基础教育改革难以突破.为此,应将基础教育与九年义务教育制度重合起来,使之成为国家提供的普惠全体人民的国民基础教育.同时,确立高中阶段教育独立的学制地位,建立基础教育后的多元化分流机制,为沟通基础教育与其他阶段教育的创造制度环境.     

在新的信息与技术环境中感受图书馆的律动──2008年的中外图书馆事业和理论研究

盘点2008年,作者们将焦点定位于中外图书馆理论与事业的5个表现更为突出的领域：基础理论、事业建设、服务、信息技术和技术应用。通过对这些领域中“亮点”的捕捉,使读者能更加快速、准确地把握住2008年图书馆学的脉动。     

高职环保专业实验、实训教学改革的探讨

实验、实训在高职人才培养过程中起着不可替代的重要作用.针对当前高职院校环境类专业实验、实训教学过程中存在的问题,提出以就业为导向、优化教学内容、拓展实训基地、建设双师队伍、加强教学管理的改革建议.     

Effects of operative conditions on membrane fouling of jet loop membrane bioreactor

The orthogonal experiments, which involves three factors： aeration intensity, suction time and suction suspended time, were designed to research membrane fouling of jet loop membrane bioreactor （JLMBR）. Experimental results indicate that increasing aeration intensity, reducing suction time and increasing suction suspended time all could mitigate membrane fouling effectively. However excessive aeration intensity, too short suction time and excessive suction suspended time were bad for bioreactor running. The optimal aeration intensity, suction time and suction suspended time were 0.75 1.00 m3/（m2.h）, 8 -10 min and 4 -5 min, respectively. The three factors all had effect on membrane pollution rate, while the suction time was the most important one and followed by aeration intensity and suction suspended time. It also indicates that, comparing with traditional submerged membrane bioreactors, JLMBR had lower membrane pollution rate.     

发挥高校科研实验室作用,加强大学生创新能力培养

以培养大学生创新能力为切入点,探讨高校科研实验室利用自身优势承担大学生创新实验的基本思路,阐述高校科研实验室在大学生创新能力的培养中的作用,并且提出要进一步发挥其作用,加强大学生创新能力的培养.     

“拇指文化”对高校学生思想政治教育工作的影响及对策

“拇指文化”给高校大学生带来了正面和负面的影响。因此,必须辨证地分析这种文化现象背后的原因,全面探索“拇指文化”背景下高校思想政治工作的新发展,在宏观上积极营造健康向上的校园文化,中观上努力探索行之有效的思想政治工作途径和载体,微观上大力培养大学生自我教育与保护的意识和能力。     

基于领域本体实现Web文本挖掘研究

为弥补改进传统Web文本挖掘方法缺乏对文本语义理解的不足,采用本体与Web文本挖掘相结合的方法,探讨基于领域本体的Web文本挖掘方法。首先创建Web文本的本体结构,然后引入领域本体“概念-概念”相似度矩阵,并就概念间关系识别进行描述,最后给出Web文本挖掘的实现方法,发现Web文本信息的内涵。实验中以网络媒体报道为例,通过文本挖掘得出相关结论。     

Epigallocatechin-3-gallate affects the growth of LNCaP cells via membrane fluidity and distribution of cellular zinc

Objective: To evaluate effects of epigallocatechin-3-gallate (EGCG) on the viability, membrane properties, and zinc distribution, with and without the presence of Zn2+, in human prostate carcinoma LNCaP cells. Methods: We examined changes in cellular morphology and membrane fluidity of LNCaP cells, distribution of cellular zinc, and the incorporated portion of EGCG after treatments with EGCG, Zn2+, and EGCG+Zn2+. Results: We observed an alteration in cellular morphology and a decrease in membrane fluidity of LNCaP cells after treatment with EGCG or Zn2+. The proportion of EGCG incorporated into liposomes treated with the mixture of EGCG and Zn2+ at the ratio of 1:l was 90.57%, which was significantly higher than that treated with EGCG alone (30.33%). Electron spin resonance (ESR) studies and determination of fatty acids showed that the effects of EGCG on the membrane fluidity of LNCaP were decreased by Zn2+. EGCG accelerated the accumulation of zinc in the mitochondria and cytosol as observed by atomic absorption spectrometer. Conclusion: These results show that EGCG interacted with cell membrane,decreased the membrane fluidity of LNCaP cells, and accelerated zinc accumulation in the mitochondria and cytosol, which could be the mechanism by which EGCG inhibits proliferation of LNCaP cells. In addition, high concentrations of Zn2+ could attenuate the actions elicited by EGCG.     

Optimization of conditions for supercritical fluid extraction of flavonoids from hops (Humulus lupulus L.)

Waste hops are good sources of flavonoids. Extraction of flavonoids from waste hops (SC-CO₂ extracted hops) using supercritical fluids technology was investigated. Various temperatures, pressures and concentrations of ethanol (modifier) and the ratio (w/w) of solvent to material were tested in this study. The results of single factor and orthogonal experiments showed that at 50°C, 25 MPa, the ratio of solvent to material (50%), ethanol concentration (80%) resulted in maximum extraction yield flavonoids (7.8 mg/g). HPLC-MS analysis of the extracts indicated that flavonoids obtained were xanthohumol, the principal prenylflavonoid in hops. Project (No. Y304203) supported by the Natural Science Foundation of Zhejiang Province, China     

Effects of fructose-1,6-diphosphate on concentration of calcium and activities of sarcoplosnic Ca^2＋-ATPase in cardiomyocytes of Adriamycin-treated rats

Objective: To observe the effects of fructose-1,6-diphosphate (FDP) on serum levels of cardiac troponin 1 (cTnl) and creatine kinase-MB (CK-MB), as well as the concentration of calcium in cardiomyocytes (Myo[Ca2 ]) and activity of sarcoplosnic Ca2 -ATPase (SRCa2 -ATPase) in Adriamycin (ADR)-treated rats. Methods: Rats were intraperitoneally injected with ADR (2.5 mg/kg every other day for 6 times) and then with different dosages of FDP (every other day for twenty-one times). Bi-antibodies sandwich Enzyme linked immune absorption assay (ELISA) was performed to detect serum level of cTnl. CK-MB was detected by monoclonal antibody, Myo[Ca2 ] was detected by fluorescent spectrophotometry and the activity of SRCa2 -ATPase was detected by inorganic phosphate method. Results: FDP (300, 600, 1200 mg/kg) significantly reduced the serum levels of cTnl and CK-MB, while at the same time decreased calcium concentration and increased SRCa2 -ATPase activity in cardiomyocytes of ADR-treated rats (P<0.01). Conclusions: FDP might alleviate the cardiotoxic effects induced by ADR through decreasing calcium level as well as increasing SRCa2 -ATPase activity in cardiomyocytes.