Assessment of highway slope failure using neural networks

An artificial intelligence technique of back-propagation neural networks is used to assess the slope failure. On-site slope failure data from the South Cross-Island Highway in southern Taiwan are used to test the performance of the neural network model. The numerical results demonstrate the effectiveness of artificial neural networks in the evaluation of slope failure potential based on five major factors, such as the slope gradient angle, the slope height, the cumulative precipitation, daily rainfall and strength of materials.     

Chlorella vulgaris triggers apoptosis in hepatocarcinogenesis-induced rats

Chlorella vulgaris (CV) has been reported to have antioxidant and anticancer properties. We evaluated the effect of CV on apoptotic regulator protein expression in liver cancer-induced rats. Male Wistar rats (200∼250 g) were divided into eight groups: control group (normal diet), CDE group (choline deficient diet supplemented with ethionine in drinking water to induce hepatocarcinogenesis), CV groups with three different doses of CV (50, 150, and 300 mg/kg body weight), and CDE groups treated with different doses of CV (50, 150, and 300 mg/kg body weight). Rats were sacrificed at various weeks and liver tissues were embedded in paraffin blocks for immunohistochemistry studies. CV, at increasing doses, decreased the expression of anti-apoptotic protein, Bcl-2, but increased the expression of pro-apoptotic protein, caspase 8, in CDE rats, which was correlated with decreased hepatoctyes proliferation and increased apoptosis as determined by bromodeoxy-uridine (BrdU) labeling and terminal deoxynucleotidyl transferase mediated dUTP nick-end labeling (TUNEL) assay, respectively. Our study shows that CV has definite chemopreventive effect by inducing apoptosis via decreasing the expression of Bcl-2 and increasing the expression of caspase 8 in hepatocarcinogenesis-induced rats. Project supported by Department of Biochemistry, Faculty of Medicine, UKM Medical Center, Universiti Kebangsaan Malaysia, and the Malaysian Ministry of Science and Technological Innovation (MOSTI)     

Exploring the orientations of international students in Mexico: differences by region of origin

This study examined the dispositions, experiences, and expectations of international students in a developing country to understand the increasing phenomenon of reverse student flows and the role of the political economy in international student mobility. Students’ dispositions, experiences and expectations—referred here collectively as “orientations”—served as the guiding framework for this study. Data were drawn from survey responses from 279 international students at universities throughout Mexico and analyzed to explore the orientations among students from Europe, Latin America and North America. Findings showed significant differences among international students’ dispositions, experiences, and expectations by these geographical regions of origin. In a broader context, this research addressed the important role of developing countries as not only senders but also receivers of international students. This research also demonstrated the ways that the political economy shape the orientations of students studying abroad.     

Impact of the excise tax on firm R&D and performance in the medical device industry: Evidence from the Affordable Care Act

This article examines how the excise tax affects firms’ R&D investment, performance, and market strategy in the US medical device industry. The Affordable Care Act imposed a 2.3% excise tax on medical devices beginning in January 2013, and thus this study compares the medical device firms with other high-tech firms before and after the tax incidence. Using COMPUSTAT data from 2006 to 2015, the author finds that the excise tax reduced R&D investment, sales revenue, gross margins, and earnings for medical device firms. In addition, the excise tax increased their global market sales intensity, global market diversification, and customer diversification in the US domestic market.     

Improved stability conditions of time-varying delay systems based on new Lyapunov functionals

This paper is concerned with the stability analysis of time-varying delay systems. Unlike the construction of augmented Lyapunov functional and multiple integral Lyapunov functional, novel three Lyapunov functionals are suggested which are delay product type functions and lead to less conservative results. Based on newly developed Lyapunov functionals, three stability criteria are derived and their superiority is described by three numerical examples.     

An improved stability criteria for neutral-type Lur’e systems with time-varying delays

This paper improves stability criteria for neutral-type Lur’e systems with time-varying delays, where the nonlinearity satisfies sector and slope restrictions. A proposed Lyapunov–Krasovskii functional consisting of a quadratic term and integral terms for the time-varying delays and the nonlinearities, has four different characteristics. First, the quadratic term utilizes not only the current and delayed states but also the nonlinear vectors. Second, the integral terms for nonlinearities fully exploit the characteristics of sector and slope restrictions. Third, the integral terms for nonlinearities also exploit the characteristic of incremental restriction induced from the slope restriction. Fourth, this paper utilizes a vector related to the time derivative of the neutral delayed state to handle the neutral delay. Based on the proposed Lyapunov–Krasovskii functional, the improved stability criteria are derived in terms of linear matrix inequalities. Numerical examples show that the proposed criteria present less conservative results than the previous criteria.     

Reproducibility of measurement techniques used for creatine kinase,interleukin-6 and high-sensitivity C-reactive protein determination over a 48 h period in males and females

To examine the reproducibility of three measurement techniques used to determine creatine kinase, interleukin-6 and high-sensitivity C-reactive protein, 50 participants had blood samples taken on two occasions. Fingertip plasma samples were analysed using the Reflotron for CK determination. Venous blood samples collected into serum separator tubes were used for IL-6 and hs-CRP analyses. IL-6 was measured using an enzyme linked immune assay development kit. The hs-CRP was measured by an in-house ELISA method. Dependent t-tests showed no systematic bias between samples. The interdian CV was 20.0% for CK, 15.3% for IL-6 and 44.2% for hs-CRP. The intraclass correlation coefficient was 0.90 for CK, 0.98 for IL-6 and 0.70 for hs-CRP. The 95% limits of agreement were ?69.7 to 63.5 IU/L for CK, ?1.48 to 1.80 pg/ml for IL-6 and ?1.10 to 0.91 µg/L for hs-CRP. The results demonstrate low absolute reproducibility, which may obscure a true experimental effect.     

Rotational and linear head accelerations from taekwondo kicks and punches

The purpose was to compare rotational and linear head accelerations as a result of taekwondo kicks and punches. Taekwondo athletes executed five repetitions of the turning kick, spinning hook kick, hook punch, straight punch, and jab punch to a Hybrid III Crash Test Dummy head-neck complex. A tri-axial accelerometer and an angular rate sensor were mounted inside the Hybrid III head to measure resultant linear (RLA) and rotational accelerations. The Hybrid III was fixed to a height-adjustable frame and fitted with protective taekwondo headgear. Dummy head height was positioned to each participant’s standing height. Acceleration data were processed in accordance with SAE J211-1.There was no significant multivariate difference in RLA but the effect was not clear. Univariate follow-up analysis showed a significant difference in RLA but the effect was also not clear. There was no difference in rotational acceleration. The highest RLA and rotational acceleration were produced, in order, by the turning kick, hook kick, hook punch, straight punch, and jab. These data are clinically important as they provide a better understanding of the biomechanical injury measures and support for improved headgear testing methodology.     

An institutional analysis of an e-government system for anti-corruption: The case of OPEN

E-government is increasingly being used to improve transparency in the government sector and to combat corruption. Using institutional theory as an analytical perspective, this study documents and evaluates the development of an anti-corruption system called OPEN (Online Procedures ENhancement for civil application) in the Seoul Metropolitan Government. Incorporating three distinctive (yet interrelated) dimensions of institutionalization (regulatory/coercive, cognitive/mimetic, and normative), and four anti-corruption strategies embedded in the system, this study investigates how an e-government system for anti-corruption in a local government has evolved and become a prototype of a national system to be used for the same purpose. The findings show that in implementing OPEN, a system for anti-corruption, the regulatory dimension was most effective, and (as in many IS implementations) strong leadership was crucial to its success.