跨语言文献检索系统研究

[目的/意义]旨在探讨解决原英日文献检索分析中存在的不足,实现以中文为检索语言的中、英、日文献资源的统一检索。[方法/过程]介绍了一种通过机器翻译技术实现以中文为检索语言的中日英文献资源的统一检索系统。[结果/结论]该系统基于MASH-UP技术将检索结果整合进行统一的内容分析,帮助用户跨越语言的障碍,方便地查询和使用外文文献。     

Ecological principle meets cancer treatment: treating children with acute myeloid leukemia with low-dose chemotherapy

Standard chemotherapy regimens for remission induction of pediatric acute myeloid leukemia (AML) are associated with significant morbidity and mortality. We performed a cohort study to determine the impact of reducing the intensity of remission induction chemotherapy on the outcomes of selected children with AML treated with a low-dose induction regimen plus granulocyte colony stimulating factor (G-CSF) (low-dose chemotherapy (LDC)/G-CSF). Complete response (CR) after two induction courses was attained in 87.0% (40/46) of patients receiving LDC/G-CSF. Post-remission therapy was offered to all patients, and included standard consolidation and/or stem cell transplantation. During the study period, an additional 94 consecutive children with AML treated with standard chemotherapy (SDC) for induction (80/94 (85.1%) of the patients attained CR after induction II, P = 0.953) and post-remission. In this non-randomized study, there were no significant differences in 4-year event-free (67.4 vs. 70.7%; P = 0.99) and overall (70.3 vs. 74.6%, P = 0.69) survival in the LDC/G-CSF and SDC cohorts, respectively. After the first course of induction, recovery of white blood cell (WBC) and platelet counts were significantly faster in patients receiving LDC/G-CSF than in those receiving SDC (11.5 vs. 18.5 d for WBCs (P < 0.001); 15.5 vs. 22.0 d for platelets (P < 0.001)). To examine the quality of molecular response, targeted deep sequencing was performed. Of 137 mutations detected at diagnosis in 20 children who attained hematological CR after two courses of LDC/G-CSF (n = 9) or SDC (n = 11), all of the mutations were below the reference value (variant allelic frequency <2.5%) after two courses, irrespective of the treatment group. In conclusion, children with AML receiving LDC/G-CSF appear to have similar outcomes and mutation clearance levels, but significantly lower toxicity than those receiving SDC. Thus, LDC/G-CSF should be further evaluated as an effective alternative to remission induction in pediatric AML.     

医药冷链物流在物联网环境下的动态风险评估

首先运用流程图法分析造成物联网环境下医药冷链物流各环节风险的众多因素源,并运用熵权法对风险指标客观赋权建立风险因素评估指标体系,然后利用Ge NIe软件建立动态贝叶斯网络模型对风险环节的关键风险因素进行概率评估。结果显示在风险评估中运输环节风险的发生概率最高,同时企业关于设备的验证选型是影响物联网医药冷链的关键风险因素,这为企业和政府控制药品质量安全管理提供了依据。     

供给侧结构性因素对产业生态效率影响的实证研究——基于中国纺织业的DEA-Tobit分析

选取结构性污染较严重的产业——纺织业作为研究对象,采用DEA-Tobit两阶段模型对纺织业生态效率作评价并分析纺织业生态效率的结构性因素。实证结果表明,能源消费结构指标与纺织业生态效率显著正相关,产业结构指标和产业组织结构指标与之负相关,而对外贸易结构指标的影响不是很显著,环境规制指标也对其有显著影响。因此,应从能源结构、要素替代、产业集中和加强执法4个方面来促进纺织产业生态化的实现。     

股票期权激励计划实施中的研发支出行为研究

以2010-2012年宣告实施股票期权激励计划并进行行权的上市公司为研究对象,研究股票期权激励计划对公司研发支出行为的影响。发现,在基数期公司研发支出强度与是否实行股票期权激励计划呈显著正相关;而在行权等待期公司研发支出强度变化与是否实行股票期权激励计划呈显著负相关,说明经理人存在很强的动机利用研发支出进行盈余操纵,以获取由股票期权激励带来更大的经济利益;研究还发现,经理人管理权力加剧了这种操纵行为,作为嵌入公司治理结构保护中小股东利益的独立董事制度发挥了一定的治理作用。本研究结论为政策制定者调整相关股权激励政策提供了参考。     

游戏化:情报学视阈下研究生信息素养教育新范式

[目的/意义] 研究生教育作为国民教育序列的顶端,肩负着"高端人才供给"和"科学技术创新"的双重使命,对实现国家战略、支撑现代化强国建设具有重大意义。大数据时代对我国研究生信息素质提出更高的要求,也对高校传统信息素养教育发起挑战。[方法/过程] 文章综合运用情报学、传播学与高等教育学跨学科研究方法,以情报学视角论述研究生信息素养教育引入游戏化机制的必要性,随后对美国高校游戏化信息素养教育现状展开探讨,通过对比研究获取信息有效传播路径及优势教育经验。[结果/结论] 最后基于情报学视角提出我国研究生信息素养教育游戏化策略,形成以"游戏设计服务需求、协同宣传与媒介推广、强化游戏馆员内生动力、优化游戏化学习体验"四位一体创新体系。     

外部知识源化、知识积累与中国工业绿色增长——动态异质门槛效应研究

针对开放式创新驱动与绿色发展融合下工业绿色增长路径及动力来源多元化特征，基于中国工业2009-2015省际面板数据，通过考虑非期望产出的Super-SBM模型测算环境和能源约束下的工业绿色增长结构，并采用改进的动态门槛回归模型，从地区知识积累视角系统探究外部知识源化路径驱动工业绿色增长机制的知识积累动态门槛效应及其时空异质性。研究表明：中国工业绿色增长整体水平较低，地区异质性显著；总体上，外部知识源化对工业绿色增长起到了正向作用，但其存在显著的知识积累异质门槛特征：知识积累一旦突破了临界规模，外部知识源化路径驱动工业绿色增长的正向效应则呈现减弱，且知识积累门槛时空分布存在较大差异。     

专业虚拟社区的用户创新激励——基于社会网络分析

研究在专业虚拟社区中如何激励用户创新.提出专业虚拟社区成员创新的影响因素为社交需求、获得关注需求、自我实现需求以及社区联结程度;通过社会网络分析法识别意见领袖,并以意见领袖为中心构建成员网络关系,分为中间层、边缘层和意见领袖;基于成员网络关系,结合创新的影响因素分析成员创新行为产生的动机,并以MIUI社区为例进行实证分...     

Adaptive output feedback fault tolerant control for uncertain nonlinear systems based on actuator switching

In this paper, an adaptive output feedback fault tolerant control (FTC) based on actuator switching is proposed for a class of single-input single-output (SISO) nonlinear systems with uncertain parameters and possible actuator failures, for which a set of healthy actuators are available as backups. While high-gain K-filters are utilized to estimate the unmeasured states, an adaptive control law is designed to compensate for the parameter uncertainties and certain actuator failures, an actuator switching strategy based on a set of appropriately designed monitoring functions (MFs) is proposed to tackle those serious actuator failures, make tracking error satisfy prescribed transient and steady-state performance and guarantee closed-loop signal boundedness.