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301.
Dinesh C. Sharma Deepa Chandiramani Manminder Riyat Praveen Sharma 《Indian journal of clinical biochemistry : IJCB》2007,22(2):123-128
A number of preparations are available in Ayurved for treatment of anemia and iron deficiency. This study was designed to
evaluate efficacy of some of them. Six most commonly used Ayurvedic iron containing preparations (Navayasa Curna, Punarnavadi Mandura, Dhatri Lauha, Pradarantaka Lauha, Sarva-Juara-Hara Lauha and Vrihat Yakrdari Lauha) were given in a dose of 250 mg b.d. for 30 days to six groups of iron deficient anemic patients; each group consisting of
20 patients. A control group was given Allopathic preparation—Irex-12, (containing—ferrous fumarate, vitamin C, folic acid
and vitamin B12); 1 capsule daily for 30 days for comparison. All hematological and iron parameters were determined before and after completion
of treatment. The results showed that there was statistically significant rise (p<0.001) in all of them—Hb, PCV, TRBC, MCV,
MCH, MCHC and plasma iron, percent saturation and plasma ferritin. Total iron binding capacity decreased significantly (p<0.001).
The response of most of Ayurvedic preparations was better than Allopathic preparation and there was no side effect as observed
with iron salts The Hb regeneration rate was 0.10 g/dl/day for Allopathic preparation; while it was above this value for all
Ayurvedic preparations exceptPradarantaka Lauha which was least effective.Sarva-Juara-Hara Lauha was the drug of choice as Hb regeneration with it was highest 0.16 g/dl/day. Upon analysis of Ayurvedic drugs, these results
were found to be consistent and correlated with iron content of the preparation. 相似文献
302.
Chitra Upadhyaya Sandhya Mishra Peeyush Ajmera Praveen Sharma 《Indian journal of clinical biochemistry : IJCB》2004,19(2):48-52
Pregnancy is associated with increased demand of all the nutrients like Iron, Copper, Zinc etc. and deficiency of any of these
could affect pregnancy, delivery and out come of pregnancy. With this consideration, the study was conducted on 80 mothers
and newborns and 20 age matched control women. Out of 80 mothers, 34 had Iron deficiency anemia and their Hb levels were below
9.0 gm/d1. Pregnant women had significantly lower Iron and Zinc levels while Copper and Total Iron Binding Capacity (TIBC) were significantly
higher (P<0.001). Newborns had significantly elevated Iron and Zinc levels and low levels of Copper and TIBC as compared to
their mothers irrespective of Iron deficiency anemia. Micronutrient status of newborn was found to be dependent on their mother's
micronutrient status. Besides, results also suggest micronutrient interactions, which are reflected in Iron/Zinc, Iron/Copper
and Zinc/Copper ratios. In view of this, there is need for proper, adequate and balanced micronutrient supplementation during
pregnancy to affect a healthy outcome. 相似文献
303.
Ranjana Singh Sumita Sharma Raj K. Singh Germaine Cornelissen 《Indian journal of clinical biochemistry : IJCB》2016,31(2):215-223
The circadian rhythm of human circulating lipid components was studied under nearnormal tropical conditions in 162 healthy volunteers (103 males and 59 females; 7 to 75 years of age). They followed a diurnal activity from about 06:00 to about 22:00 and nocturnal rest. These volunteers were divided into four groups: Group A (7–20 years), Group B (21–40 years), Group C (41–60 years) and Group D (61–75 years), comprising 42, 60, 35 and 25 participants, respectively. A marked circadian rhythm was demonstrated for each studied variable in each group by population-mean cosinor analysis (almost invariably p < 0.001). Furthermore, circadian rhythm characteristics were compared among the 4 groups by parameter tests and regressed as a function of age, separately for males and females. A second-order polynomial characterized the MESOR of HDL cholesterol, phospholipids and total lipids, as well as the 24-h amplitude of total cholesterol and phospholipids. The 24-h amplitude of total lipids decreased linearly with age. The 24-h acrophase of the oldest age group (Group D) was advanced in the case of total cholesterol, HDL cholesterol, and total lipids, whereas that of phospholipids was delayed. Mapping the circadian rhythm (an important component of the broader time structure or chronome, which includes a. o., trends with age and extra-circadian components) of lipid components is needed to explore their role in the aging process in health. 相似文献
304.
Detection of lgE and lgG antibodies in Aspergillosis is of diagnostic significance. The serological methods, such as agglutination, gel diffusion and counter immuno electrophoresis that are commonly used in the laboratories for diagnosis of Aspergillus induced infections, are less sensitive and high cross reactivity is often encountered. We carried out work on characterization and identification of diagnostically relevant antigens ofA. fumigatus. Well characterized antigens were used to develop an ELISA with 92% sensitivity and 89% specificity for detection of specific lgE and lgG in the sera of patients of allergic bronchopulmonary aspergillosis (ABPA), aspergilloma and invasive aspergillosis. Subsequently, a sample kit having “ready to use type” of dry reagents (powder/tableted buffers and lyophilized antigen, conjugate and reference sera) was formulated. The kit was validated with sera from patients of ABPA, related allergic disorders, tuberculosis, post-Kochs cases and thalassemic children receiving repeated blood transfusions. The performance of the kit was found to be satisfactory with coded sera. 相似文献
305.
S. K. Mathur Piyush Chandra Sandhya Mishra Peeyush Ajmera Praveen Sharma 《Indian journal of clinical biochemistry : IJCB》2007,22(2):70-73
Asian Indians are known to be at a higher risk of developing T2DM, but the underlying genetic factor in this population is
still not well understood. T2DM is a complex genetic trait and assessment of disease related intermediate phenotypic traits
is an important initial step towards any systematic genomic study. Therefore, in the present study we have assessed diabetes
related intermediate phenotypic traits of insulin secretion and insulin resistance in the patients belonging to this population.
The study included 157 T2DM patients of either sex ranging in age from 45–80 years and 84 non-diabetic subjects with no family
history of diabetes, ranging in age from 45 to 75 years served as controls. Intermediate phenotypic traits studied were BMI,
W: H ratio, fasting free fatty acid level and Insulin resistance and secretion. Diabetics were found to have significantly
higher W: H ratio (p<0.001), FFA (p<0.001) and HOMA-R (p<0.001) as compared to non-diabetics. However, there was no significant
difference in their BMI and HOMA-β. There was a positive correlation between FFA level and HOMA-R among diabetics, but not
among controls. These findings suggest that in abdominal obesity FFA mediated insulin resistance is an important causative
factor underlying T2DM in this population. Moreover, comparable HOMA-β in diabetics reflects compensatory insulin hyper secretion
in these subjects. There is a need to examine relative contribution and precise nature of genetic factor in their tendency
for central obesity, free fatty acidemia and insulin resistance. 相似文献
306.
307.
Larry Napoleon Debra Freedman Koushik Seetharaman Priya Sharma 《Journal of Food Science Education》2006,5(2):19-23
ABSTRACT: This article describes the outcomes of a needs assessment concerning current training needs and performance targets for non-degreed employees in the food industry. Focus groups were used to gather data from 5 food-processing companies: a fresh vegetable company, a canned vegetable company, 2 snack food companies, and a meat company. Focus group participants consisted of 1 senior-level manager each from human resource, production, quality assurance, purchasing, and product development departments within each company. The needs assessment identified 4 major themes that employers indicated as beneficial knowledge and skills for employees to possess: safety training, knowledge of food and production systems, learning and applying mathematical skills, and professional conduct. The authors anticipate that the knowledge of industry needs, with respect to the desired incoming workforce competencies and knowledge, will facilitate the development of integrated curriculum modules for secondary career and technical education programs (high school grades). These integrated curriculum modules will address the growing needs of the food industry and facilitate the development of employment skills required to function and prosper in the new global economy. 相似文献
308.
N.Mukund Sharma V.Prabhu Dev 《东南大学学报》2008,(Z1)
The increased volatility in the foreign exchange market in recent years has increased the foreign exchange risk faced by companies worldwide. This phenomenon holds good in the Indian context also. This paper tries to report on the foreign exchange risk-management practices among Indian IT (information technology) companies. The results are consistent with expectations that foreign exchange risks faced by Indian IT companies is very high especially in the light of the recent appreciation of the rupee against the USD and most of the companies are using all the available techniques to mitigate the risks. The evidence suggests that the forward cover is the most widely used derivative instrument in managing the risks and the respondents taking part in the survey believe that the government is failing in maintaining a stable exchange rate. 相似文献
309.
310.
M. Abu Zaid K. K. Sharma S. I. Rizvi 《Indian journal of clinical biochemistry : IJCB》2002,17(2):27-32
Aqueous extract of the wood ofPterocarpus marsupium, commonly known as ‘bijasar’, is used in Indian Ayurveda system of medicine for treatment of diabetes. The active anti-diabetic
principle in its aqueous extract has been found to be (-)epicatechin, a flavonoid. The present work was undertaken to study
the effect of (-)epicatechin on erythrocyte membrane Ca++-ATPase from type 2 diabetic patients. The activity of erythrocyte Ca++-ATPase was significantly lower in type 2 diabetics.In vitro insulin treatment of erythrocyte ghosts, resulted in the increase of Ca++-ATPase activity in diabetic patients. Treatment with (-)epicatechin (1mM) resulted in an increase in the activity of erythrocyte
Ca++-ATPase in both normal individuals and type 2 diabetic patients. The insulin like effect of (-)epicatechin on erythrocyte
membrane Ca++-ATPase in type 2 diabetics is an interesting finding. Further work is needed to elucidate the mechanism of action of (-)epicatechin
on modulation of erythrocyte membrane bound enzymes. 相似文献