创新型人才培养的内生动力问题刍议

内生动力不足制约着创新型人才培养。高校创新型人才培养的根本问题是突破既有人才培养模式赖以延续的利益格局,打破高校人才培养的路径依赖,通过重塑高校社会利益关系,构建创新型人才培养的动力机制。为此,必须建立高校教师充满生机与活力的教学工作机制,构建人才培养模式创新的利益与责任机制,以使创新型人才培养成为教师的自觉追求。     

探索情趣质疑教学法培养学生自主学习

笔者曾尝试采取情趣质疑教学法教学与采用常规的教学法教育学生,学习的效果有明显的区别.前者,学生在愉悦的氛围中提高学习兴趣,疑点解决了,学习成绩提高了,后者则是进入填鸭式注入式的胡同.经过多年探索,笔者认为,情趣质疑教学法强调情趣作基础,质疑为核心,依靠创设情趣,激发学生学习兴趣,刺激求知欲望,产生积极的心理反应;使思维达到最佳程度,从而积极主动地参与教学活动,形成了良好的学习习惯.     

食品添加剂对食品安全的影响

自“三鹿奶粉”事件之后,食品添加剂的安全性问题已成为人们普遍关注并亟待解决的热门问题．食品添加剂使用中存在的问题及食品添加剂使用不当影响了食品安全性,必须加强食品添加剂使用管理．     

AutoCAD的高级应用

AutoCAD除了优越的平面绘图功能,还具有与其他诸如UG等三维建模软件相似的三维造型功能。本文通过在AutoCAD中对三维实体快速生成二维视图的深入研究,给出了具体操作方法和相关技巧。实践证明,将复杂的三维实体设计与工程制图工作统一起来的AutoCAD高级应用,对减轻绘制工程技术文件的工作量,扩展Au-toCAD使用范围有着积极的工程实际意义。     

军校考试成绩分析的新思路

利用统计学中的偏态和峰度指标分析成绩的总体分布,对试题的难度、区分度进行深入研究,解决了目前军校考试成绩分析通过正态检验方法的弊端.运用Excel和VBA实现了考试成绩分析系统,为学员学习情况和教员授课效果提供客观评价,对试题库的建立和更新提供依据.     

现代学徒制试点的实施路径探析

现代学徒制试点是我国深化产教融合、健全职业技能培训体系,推动职业教育高质量发展的重要形式。现代学徒制试点的实施路径是否合理,是关系到我国现代学徒制试点专业教育能否顺利开展的前提。基于此,文章在对现代学徒制试点的提出背景、实施主体的认识误区、实施原则及实施路径设计思路作全面分析基础上,进而重点对现代学徒制试点的实施路径进行了深入探索,即如何选择合作企业、选拔导师团队、制定学徒培养方案、校企联合培养以及教育教学资源建设,并对实践个案作简要概述,同时提出了相关建议与思考。     

Effect of high glucose levels on the calcification of vascular smooth muscle cells by inducing osteoblastic differentiation and intracellular calcium deposition via BMP-2/Cbfα-1 pathway

In this paper,we investigate the effect and the possible mechanism of high glucose levels on the calcification of human aortic smooth muscle cells (HASMCs).HASMCs were divided into four groups: normal glucose group (NG),osmolality control group (OC),high glucose group (HG,HASMCs culture medium containing 30 mmol/L glucose),and high glucose plus recombinant human Noggin protein (bone morphogenetic protein-2 (BMP-2) antagonist) group (HN).The mRNA levels and the protein expressions of BMP-2 and core binding factor alpha-1 (Cbfα-1) were measured by real-time quantitative polymerase chain reaction (PCR) and Western blot.After induced by 10 mmol/L β-glycerol phosphoric acid,cells were harvested for assessments of alkaline phosphatase (ALP) activities at Days 1,2,and 3,and intracellular calcium contents at Days 7 and 14,respectively.High glucose levels increased the mRNA levels and the protein expressions of BMP-2 and Cbfα-1 (P0.05).The expression of Cbfα-1 was partially blocked by Noggin protein (P0.05),while BMP-2 was not (P0.05).After being induced by β-glycerol phosphoric acid,high glucose levels increased the ALP activity [(48.63±1.03) vs.(41.42±2.28) U/mg protein,Day 3;P0.05] and the intracellular calcium content [(2.76±0.09) vs.(1.75±0.07) μmol/mg protein,Day 14;P0.05] in a time-dependent manner when compared with the NG group,while the ALP activity could not be blocked by Noggin protein [(48.63±1.03) vs.(47.37±0.97) U/mg protein,Day 3;P0.05].These results show that high glucose levels can evoke the calcification of HASMCs by inducing osteoblastic trans-differentiation and intracellular calcium deposition via the BMP-2/Cbfα-1 pathway,which can be partially blocked by Noggin protein.     

高等教育:观念与现实之间的问题及应对

教育目的的实现需要条件,如果条件不具备或这些条件之间的关系不匹配,都可能成为实现教育目的的障碍.针对目前高等教育教学中普遍存在的四大问题,应用以下几方面的思路去应对:价值取向上应侧重对人的培养;知识论上,应侧重不确定性知识;方法论上,应侧重创新性学习;评价观上应侧重对价的评估.     

Estimation of financial loss ratio for E-insurance: a quantitative model

In view of the risk of E-commerce and the response of the insurance industry to it, this paper is aimed at one important point of insurance, that is, estimation of financial loss ratio, which is one of the most difficult problems facing the E-insurance industry. This paper proposes a quantitative analyzing model for estimating E-insurance financial loss ratio. The model is based on gross income per enterprise and CSI/FBI computer crime and security survey. The analysis results presented are reasonable and valuable for both insurer and the insured and thus can be accepted by both of them. What we must point out is that according to our assumption, the financial loss ratio varied very little, 0.233% in 1999 and 0.236% in 2000 although there was much variation in the main data of the CSI/FBI survey.     

体育教学中动作示范的作用及方法

动作示范是体育教学中最常用的一种直观教学法。它是教师通过具体的动作示范,使学生在头脑中建立起所要学习的动作的表象,以了解所学动作的结构、要领的方法。