隔姜灸加超短波治疗急性细菌性痢疾31例临床观察

笔者于1997～2000年间运用隔姜灸配合超短波,治疗急性细菌性痢疾31例,取得了较满意的疗效,现报告如下:     

谨防小儿脓疱疮诱发肾炎

脓疱疮俗称黄水疮,是一种常见的由化脓性球菌引起的急性炎症皮肤病,具有接触传染特征。脓疱疮90%以上见于儿童,以1-4岁为高发年龄,症见皮肤上发生小红疹子、水疱或脓汁沉于疱底、呈半月型积脓状的大疱、脓疱,疱易破溃,流黄水,结脓痂,患儿自觉瘙痒,一般无全身症状。由于接触传染     

Cell therapy in congestive heart failure

Congestive heart failure （CHF） has emerged as a major worldwide epidemic and its main causes seem to be the aging of the population and the survival of patients with post-myocardial infarction. Cardiomyocyte dropout （necrosis and apoptosis） plays a critical role in the progress of CHF; thus treatment of CHF by exogenous cell implantation will be a promising medical approach. In the acute phase of cardiac damage cardiac stem cells （CSCs） within the heart divide symmetrically and/or asymmetrically in response to the change of heart homeostasis, and at the same time homing of bone marrow stem cells （BMCs） to injured area is thought to occur, which not only reconstitutes CSC population to normal levels but also repairs the heart by differentiation into cardiac tissue. So far, basic studies by using potential sources such as BMCs and CSCs to treat animat CHF have shown improved ventricular remodelling and heart function. Recently, however, a few of randomized, double-blind, placebo-controlled clinical trials demonstrated mixed results in heart failure with BMC therapy during acute myocardial infarction.     

Effect of a distal protection device on epicardial blood flow and myocardial perfusion in primary percutaneous coronary intervention

Objective: The beneficial effect of percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) has been well established, but there is the problem of no-reflow phenomenon which is an adverse prognostic factor in primary PCI. In the present study the effect of a distal protection device (PercuSurge GuardWire; GW) on epicardial blood flow and myocardial perfusion was evaluated. Methods and Results: Patients with AMI were randomly divided into 2 groups, the GW and the control groups. The GW group included 52 patients with AMI who underwent primary PCI with GW protection and the control group included 60 patients who underwent primary PCI without GW protection. Epicardial blood flow in the infarct-related artery (IRA) and myocardial perfusion were evaluated according to the thrombolysis in myocardial infarction (TIMI) flow grade and the myocardial blush grade (MBG). We found TIMI score of 3 was obtained significantly more frequently in the GW group (96%) than in the control group (80%). The MBG score of 3 was obtained also significantly greater in the GW group (65%) than in the control group (33%). Conclusion: Primary PCI with GW protection can significantly improve epicardial blood flow and myocardial perfusion.     

可悲的“价值实现”

一位同事的就读于北京大学的女儿突然查出了急性白血病,得悉这一消息大家无不忧心如焚,纷纷献计献策,捐钱捐物。另有一名同事的孩子正读高三,闻讯后抛出了一句让大伙儿谁也意     

西藏地区表现为Opalski综合征的急性缺血性脑卒中

目的 总结Opalski综合征的诊治经验,提升临床对该疾病的诊治效率。方法 详细分析1例高原地区发生的Opalski综合征的临床、检验和影像学资料,并结合文献检索总结33例特点。结果 33例患者中发病年龄在26～86岁之间,男性22人,占比66%,女性11人,占比33%.临床表现中为偏瘫100%、感觉障碍78%、眩晕66%、恶心呕吐45%,被发现的体征中Horner征48%、babinski(+)39%、眼震21%.影像学表现中延髓及高颈段梗死81%,小脑、枕叶梗死占27%,PICA或椎动脉闭塞或狭窄54%,椎动脉夹层12%.结论 Opalski综合征常表现为偏瘫、感觉障碍、眩晕、恶心呕吐等症状,体征中常见Horner征、眼震等,并非所有患者都存在babinski（+）,在临床工作中需注意相关临床特点,早期识别并给予血管再通治疗。     

脂蛋白相关磷脂酶A2、心脏型脂肪酸结合蛋白联合心电图在急性心肌梗死诊断中的应用价值

目的 探讨脂蛋白相关磷脂酶A2(Lp-PLA2)、心脏型脂肪酸结合蛋白（F-ABP）联合心电图在急性心肌梗死（AMI）诊断中的应用价值。方法 回顾性分析医院可疑AMI患者127例,根据冠脉检查结果和临床诊断标准分为AMI组（n=65）和非AMI组（n=62）。两组均接受血清TC、LDL-C、TG、NT-proBNP、Lp-PLA2、F-ABP水平检测及心电图、超声心动图检查。分析AMI组Lp-PLA2、F-ABP水平与血脂、心脏参数的相关性,评估不同指标对AMI的诊断效能。结果 126例疑似AMI患者心电图确诊AMI 58例,包括典型变化31例,非典型变化10例,ST段下移伴T波改变13例,ST段正常和T波改变4例。AMI组Lp-PLA2、F-ABP、TC、LDL-C、LVDD、NT-proBNP水平高于非AMI组（P<0.05）,LVEF水平低于非AMI组（P<0.05）。Lp-PLA2及F-ABP与TC、LDL-C、NT-proBNP、LVDD呈正相关（P<0.05）,与LVEF呈负相关（P<0.05）。以Lp-PLA2 197 ng/mL和F-ABP-0....     

补充食醋对力竭运动大鼠肾组织bax、bcl-2和p53蛋白表达的影响

目的:探讨补充食醋对急性力竭运动大鼠肾组织细胞凋亡调控基因bax、bcl-2和p53蛋白表达的影响.方法:成年雄性SD大鼠24只,随机分成3组:安静对照组、运动组和食醋组.安静对照组不运动,运动组和食醋组进行一次力竭运动.安静对照组和运动组在力竭运动前均灌胃一次生理盐水,而食醋组灌胃食醋一次.力竭运动后即刻处死大鼠,取肾组织,免疫组织化学法检测bax、bcl-2和p53的蛋白表达.结果:与安静对照组相比,运动组和食醋组bax、bcl-2和p53蛋白表达的平均光密度值(MOD)、阳性物质表达面积和阳性指数PI显著增高(P相似文献   

急性长时间运动对大鼠心肌线粒体NO、NOS水平及线粒体功能的影响

12只8周龄雌性SD大鼠随机分成对照组(6只)和运动组(6只),运动组负重游泳299±29 min后立即处理,取心肌线粒体测定线粒体RCR,随后测定心肌总NOS、mtNOS活性,心肌三型NOSmRNA表达水平,心肌细胞和线粒体中NO的含量,线粒体抑制活性氧的能力以及[Ca2 ]i.结果发现,一次性长时间运动后,尽管大鼠心肌线粒体抗氧化能力下降,但线粒体呼吸功能完好,线粒体游离钙离子浓度没有发生变化,这可能和心肌及心肌线粒体NO含量、NOS活性水平下降有关.     

中医药治疗急性发作期小儿哮喘研究概况

小儿哮喘发病率逐年升高,已成为世界关注的疾病之一.目前,哮喘急性期的西医一线用药以糖皮质激素为主,且存在无法忽视的副作用.中医药治疗哮喘疗效卓然,不良反应小,治疗方式多样且可多法联用.文章通过检索相关文献,从中医内治法、外治法以及临床观察三个方面,对近5年来中医药治疗小儿哮喘急性期的相关文献作一梳理,为未来深入研究小儿...