4种药吃不对容易出事

近日,发表在权威学术期刊《新英格兰医学杂志》上的一项研究表明,在因药物反应而住院的病人中,服用4种药物的最常见。这4种药物可分为两类,一类是治疗糖尿病的药物,包括口服降血糖药和胰岛素;另外则是针对血液系统的两种药物,华法林和口服抗血小板药。     

科技快递

"新型艾滋病"恐蔓延全球最初在拉丁美洲爆发的一种由吸血昆虫引发的致命疾病——查加斯病正在全球逐渐蔓延,因感染者患病初期的症状与艾滋病相似,所以有人把它称为"新型艾滋病"。这种疾病     

户外运动有助预防感冒

按照一般规律3、4月进入流感、感冒高发季,有的人简直是感冒＂专业户＂,只要到感冒高发季,只要身边有人＂中招＂,他必定首遭其害,问题到底出在哪里呢？有此一说流感发威多补充维生素D？国外研究发现,有些人反复感冒,可能跟缺乏维生素D有关。因为,维生素D能提高身体抵抗力,经常感冒者可以多晒晒太阳,多吃含维生素D的食物。     

4种药吃不对容易出事

近日,发表在权威学术期刊《新英格兰医学杂志》上的一项研究表明,在因药物反应而住院的病人中,服用4种药物的最常见。这4种药物可分为两类,一类是治疗糖尿病的药物,包括口服降血糖药和胰岛素;另外则是针对血液系统的两种药物,华法林和口服抗血小板药。     

冷早餐易使人抵抗力下降

吃早餐时,很多人为了节约时间,往往来不及将食物加热。医学专家提醒,常吃冷早餐会对身体造成一定的危害。     

Research on the protection effect of pioglitazone for non-alcoholic fatty liver disease （NAFLD） in rats

Objective： The prevalence of non-alcoholic fatty liver disease （NAFLD） has markedly increased. Insulin resistance has been implicated in the pathogenesis of NAFLD. This study was aimed at observing the relationship between insulin resistance and NAFLD, and evaluating the role of pioglitazone （PGZ） acting as insulin-sensitizing agents in the prevention and treatment of rat fatty liver induced by high fat feeding. Methods： The rats were separated randomly into 6 groups： model group Ⅰ were fed high fat diet for 8 weeks, PGZ prevention group were given PGZ 4 mg/（kg.d） simultaneously, while control group Ⅰ were fed normal food for 8 weeks; model group Ⅱ were fed high fat diet for 16 weeks, PGZ treatment group were given PGZ 4 mg/（kg.d） orally simultaneous with high fat diet for 8 weeks after high fat feeding for 8 weeks, control group Ⅱ were fed normal food for 16 weeks. The rats were sacrificed after 8 weeks and 16 weeks respectively. Liver weight, body weight, serum activities of alanine aminotransferase （ALT）, aspartate aminotransferase （AST）, alkaline phosphatase （ALP）, tumor necrosis factor alpha （TNF-α）, fasting blood glucose （FBG）, fasting plasma insulin （FINS）, HOMA （homeostasis model assessment） insulin resistance index （HOMA-IR）, and the liver histology of rats of all groups were assayed. Results： After 8 weeks, the liver in model group Ⅰ showed typical steatosis, accompanied with mild to moderate lobular inflammatory cell infiltration, liver indexes and serum levels of ALT, AST, ALP, TNF-α were significantly increased （P〈0.05） compared with control group Ⅰ. Whereas, the degree of hepatic injury was attenuated in PGZ prevention group, liver indexes and serum levels of ALT, ALP were significantly decreased （P〈0.05） compared with model group Ⅰ. After 16 weeks, notable steatosis, and lobular inflammation were observed in model group Ⅱ rat liver, while the degree of hepatic injury was attenuated in the PGZ treatment group. Liver index, serum levels ofALT, AST, ALP, FINS and HOMA-IR were significantly increased （P〈0.05） in model group Ⅱ compared with control group Ⅱ. Whereas, in PGZ treatment group, serum levels of AST and FINS showed decreasing tendency, liver indexes, serum levels of ALT, ALP, TNF-α and HOMA-IR were significantly decreased compared with model group Ⅱ. Conclusion： Insulin resistance plays a role in the pathogenesis of NAFLD in rats. Pioglitazone can attenuate insulin resistance and biochemical and histological injury in high fat-induced fatty liver in rats.     

实验的因变量就是观测指标吗?——2012年高考全国课标卷第39题第(2)问的讨论

<正>1题目为了探究6-BA和IAA对某菊花品种茎尖外植体再生丛芽的影响,某研究小组在MS培养基中加入6-BA和IAA,配制成4种培养基(见表1),灭菌后分别接种数量相同、生长状态一致、消毒后的茎尖外植体,在适宜条件下培养一段时间后,统计再生丛芽外植体的比率(m),以及再生丛芽外植体上的丛芽平均数(n),结果如表1所示。     

基因工程展望

自从1953年Watson和Crick阐明了DNA分子的双螺旋结构以来,生物学的发展进入了一个全新的阶段。即从整体和细胞水平跨入到分子水平。1973年,美国首先成功地将基因在体外重组并通过质粒转入细菌内,进行无性繁殖,基因工程从此应运而生。     

冷水有妙用

止鼻血:当流鼻血时,可用毛巾浸泡冷水敷前额,可帮助止血。明目:眼睛喜冷怕热,用流动冷水洗脸,则头清眼明。常年坚持,既可减少沙眼发生,又可保护视力,增强眼睛对疾病的抵抗力。治扭伤:四肢扭伤,局部淤血或按之肿硬,可立即用冷水浸敷,能使断裂血管较快闭合,控制血肿加剧,并止血镇痛。     

PLC分析胰岛素开链反应的教学实验设计

设计DTT还原胰岛素,HPLC再现A、B链开链反应过程的生物化学实验。筛选出最适还原反应条件,最佳HPLC分离条件。通过质谱（MALDI-TOF-MS）分析确定了产物的结构。实验操作简便,结果稳定,再现性好,通过本实验学生能更好地理解和掌握HPLC的分析原理、操作方法及其在生命科学研究中的重要意义。