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981.
982.
结合实例给出了MVC设计模式在J2EE Web层的一种有效的应用,并运用开源的Struts框架实现了MVC设计模式,还对MVC模式与Struts框架的内部实现机制进行了分析,并在实践中体现出MVC设计模式与Struts框架的高效和结构清晰的优点. 相似文献
983.
AJAX技术自诞生之日起就以其丰富舒适的用户体验逐渐赢得了广大用户和开发人黄的青睐,但AJAX只是致力于表现层的一种技术,设有底层技术的支持AJAX什么也做不了.J2EE是目前主流用于开发和运行企业级Web应用的一个标准,但在J2EE的发展过程中却过成了用户界面自然度低和用户体验不高;而AJAX与J2EE的融合,在底层应用J2EE规范进行实现,在用户界面上应用Ajax技术,却可以提高用户界面的自然度,极大地改善用户体验. 相似文献
984.
Rani James K. Thriveni Girija Ramaswamy Lakshmi Krishnamoorthy Geetashree Mukherjee P. P. Vijayalaxmi Deshmane P. P. Bapsy 《Indian journal of clinical biochemistry : IJCB》2008,23(4):345-351
HER-2 is overexpressed in approximately 20–30% of invasive Breast Cancer. ECD of the HER-2 protein is frequently cleaved and
released into the circulation, where it can be detected by ELISA in up to 45% of patients with metastatic breast cancer. The
objective of our study was to compare the current methods for the detection of HER-2 protein. Tissue HER-2 levels were studied
in 100 breast cancer patients by IHC and compared with serum HER-2 levels by ELISA. IHC frequency was 29%. Serum HER-2 ECD
was positive in 42% of patients. A statistically significant correlation was observed. HER-2 detected by IHC correlates significantly
with serum HER-2 levels detected by ELISA. Thus, ELISA is a reliable and economical tool to assess the HER-2 status in tumors,
when breast tissue sample is not available. 相似文献
985.
通过产业间R&D溢出效应测算方法的比较,选择投入产出法对产业研发活动的总受益者效应、总贡献者效应和产业间溢出效应加以度量,利用2002年、2005年、2007年的投入产出系数和R&D经费支出统计数据测算了我国制造业间的R&D溢出效应,并对测算结果进行了比较分析,结果表明:从横向对比看,轻纺制造业和资源加工业的产业间受益者效应较为明显,机械电子业对其他产业贡献较大;在时序特征上,各制造业间的溢出效应在不断发生变化,但具有一定稳定性。上述结论有望为政府优化科研经费投向,动态调整科研经费投入结构提供理论依据。 相似文献
986.
This paper analyses the role of national research funds in promoting scientific production in emerging economies. The study focuses on the impact of the Chilean National Science and Technology Research Fund (FONDECYT). The analysis uses data drawn from international sources of bibliometric information combined with the administrative records of the program's executing unit. To measure the program's impact, we implement a regression discontinuity (RD) design on principal researchers who applied for funding between 1988 and 1997 considering as outcomes both quantity (publications up to 2002) and quality (citations up to 2005) of their scientific production. Our results show significant and positive impact in terms of publications, but no impact in terms of quality of scientific production in the proximity of the program's threshold ranking. 相似文献
987.
N. Unni C. Sumithra R. Lakshman Lakshmi N. Leela Menon K. N. Subhakumari V. S. Sheejamol 《Indian journal of clinical biochemistry : IJCB》2015,30(2):161-166
PCOS is a heterogeneous endocrine disorder with diverse clinical presentation. Oxidative stress plays a key role in the pathophysiology of this disease. Serumhigh sensitive C-reactive protein (hsCRP), a marker of chronic low grade inflammation, is indicative of future development of cardiovascular disease. Our aim is to evaluate the oxidant status and hsCRP levels in PCOS. The study involved 61 cases and 61 controls in the age group of 18–40 years diagnosed with PCOS. Erythrocyte malondialdehyde (MDA), superoxide dismutase (SOD), serum hsCRP, gonadotrophins, thyroid stimulating hormone, prolactin, glycemic status and lipid profile were estimated. Erythrocyte MDA (p < 0.001), SOD (p = 0.007) and serum hsCRP (p < 0.001) were significantly elevated in PCOS patients than controls. Oxidative stress is present in women with PCOS along with elevated hsCRP. 相似文献
988.
Mohammad Abdi Mohammad Said Hakhamaneshi Mohammad Reza Alaei Namam-Ali Azadi Rahim Vakili Daniel Zamanfar Mohammad Taghikhani Shohreh Khatami 《Indian journal of clinical biochemistry : IJCB》2015,30(3):318-322
Methods for assaying lysosomal diseases in dried blood samples are very useful today due to its several advantages related to the stability of samples, its transportation, handled and analysis, and its potential use for newborn screening compared to traditional methods in leucocytes samples. For this reason, it is important to validate these assays before being used in routine laboratory. Because of different in biological markers based on ethnicity, we aimed this study to validation a DBS-based fluorometric assay for measurement of α-l-Iduronidase activity for diagnosis of MPS I patients in Iran. DBS samples were collected from 15 MPS I patients and 60 healthy age matched subjects. Diagnostic value, biological variance and α-l-Iduronidase activity were determined. DBS α-l-Iduronidase activity was significantly higher in male subjects than in female group. Using a cut-off level of 1.08 µmol/spot 20 h, sensitivity and specificity were 100 and 98 %. The linearity of test was proved and we showed that within-run and between run precision were 5.6 and 14.66 %. Measurement of α-l-Iduronidase activity in DBS samples is an accurate test for diagnosis of MPS I and because of its rapid shipping and simplicity to keeping, DBS-based enzyme activity could be considered as a useful diagnostic tool in this disease. 相似文献
989.
Yoshihiro Okamoto Tomoyo Mita Testuri Kodama Yoshimitsu Gotoh Naoya Fujita Takashi Fukui Toshiyuki Masuzawa 《Indian journal of clinical biochemistry : IJCB》2015,30(3):351-356
We measured serum soluble vascular endothelial growth factor receptor 1 (sVEGFR1) and receptor 2 (sVEGFR2) levels in healthy Japanese individuals in order to establish a reference value using a specific ELISA. Significant differences were observed in serum sVEGFR1 and sVEGFR2 levels between children and adults. To demonstrate the usefulness of the reference value for children, we measured serum sVEGFR1 and sVEGFR2 levels in children with diarrhea positive (D+) hemolytic uremic syndrome (HUS) as a preliminary study. Serum sVEGFR2 levels in children with HUS were markedly higher than those in healthy children from the onset of D + HUS. The reference value for healthy children in the present study will allow normal and pathological conditions to be discriminated from each other in future study 相似文献
990.