DNA计算图的最小顶点覆盖问题

自1994年Adleman发表了第一篇关于DNA分子计算的文章以来,DNA计算迅速成为活跃的研究领域。利用DNA计算解决了图的最小顶点覆盖问题,在构造了合有6个顶点10条边的图的顶点集对应的数据池之后,进行了一系列的合成、杂交、清洗、变性等生物操作。得到所有覆盖对应的DNA序列,然后通过编址得到所要求的最小覆盖。     

Mass spectrometry-based protein-protein interaction techniques and their applications in studies of DNA damage repair

Proteins are major functional units that are tightly connected to form complex and dynamic networks.These networks enable cells and organisms to operate properly and respond efficiently to environmental cues.Over the past decades,many biochemical methods have been developed to search for protein-binding partners in order to understand how protein networks are constructed and connected.At the same time,rapid development in proteomics and mass spectrometry(MS)techniques makes it possible to identify interacting proteins and build comprehensive protein-protein interaction networks.The resulting interactomes and networks have proven informative in the investigation of biological functions,such as in the field of DNA damage repair.In recent years,a number of proteins involved in DNA damage response and DNA repair pathways have been uncovered with MS-based protein-protein interaction studies.As the technologies for enriching associated proteins and MS become more sophisticated,the studies of protein-protein interactions are entering a new era.In this review,we summarize the strategies and recent developments for exploring protein-protein interaction.In addition,we discuss the application of these tools in the investigation of protein-protein interaction networks involved in DNA damage response and DNA repair.     

导致会计信息失真的原因及遏制措施探讨

随着我国社会主义市场经济体制改革的不断深入。现代企业越来越融入到经济一体化中．使得广大债权人、投资者及社会公众对企业会计信息质量要求越来越高。目前,会计信息失真已成为会计领域中的重要问题。因此,为了加大对会计行业的整顿和建设,有必要研究会计信息失真的原因,并有针对性地提出提高会计信息质量的防治措施,以确保会计信息的真实性。     

儿童文学:呵护童心

儿童世界是一个美丽的王国，童心是人世间最透明的场所。一方面，我们对儿童赞美不止，对童心向往不已，现代人梦想做回孩子，然而，另一方面，在现实生活中，随着社会的进步速度越来越快，竞争的惨烈已经蔓延到孩子的世界，当下的孩子日益失却原本属于他们的快乐，在这种情势下，儿童文学的价值因此而突显。呵护童心，保留童心，会让这个世界更美好!     

DNA’s new avatar as nanoscale construction material

DNA is fast taking on a new aspect utilizing it’s physical property of persistence length and chemical property of base pairing to build architectures in 1D, 2D and 3D. This field is called structural DNA nano-technology and is poised to revolutionize several areas ranging from materials science to cell biology.     

Damage assessment for buried structures against internal blast load

The soil-structure interaction (SSI) decoupling is applied to simplify buried structure against internal blast load as spring effect. Shear failure, bending failure and combined failure modes are considered based on five transverse velocity profiles for the rigid-plastic structural element. The critical equations for shear and bending failure are derived respectively. Pressureimpulse diagrams are accordingly developed to assess damage of the buried structures against internal blast load. Comparison is done to show influences of soil-structure interaction and shear-to-bending strength ratio of a structural element. A case study is conducted to show the application of damage assessment to a reinforced concrete beam element of buried structure.     

近亲属不明时死亡赔偿金的赔付问题——以高淳县民政局为死亡流浪者索赔案为例

笔者有意在辨明死亡赔偿金性质的基础上,在流浪者身份不明的前提下,从理论上探讨死亡赔偿金的赔付问题,希冀能为实务中类似问题的处理提供一些思路。     

论科研领域寻租活动的表现、危害与特点

本文首先根据寻租主体的不同，对科研领域的寻租活动加以分类论述。然后重点探讨了科研领域寻租活动的危害与特点。最后对如何避免科研领域的寻租活动提出了一些粗浅的建议。     

我国专利侵权赔偿额的影响因素及预测研究

首先,以我国2002—2012年的605件专利侵权诉讼案件为样本,采用多元回归方法,对我国专利侵权赔偿额的影响因素进行了定量研究,结果显示:侵权时间、侵权人数等12个变量对赔偿额有显著影响。其次,根据回归结果,选取以上12个变量,建立了BP神经网络模型,预测了专利侵权赔偿额,结果显示:该模型对0-5万元区间段赔偿额预测的正确率达94%,对5-10万元区间段赔偿额预测的正确率达68%,对10-50万区间段赔偿额预测的正确率达85%。最后,根据研究结果,提出了完善我国专利侵权赔偿制度的对策建议。     

DNA序列的3D图形表示（英文）

本文介绍一种新的DNA序列的三维图形表示，它可以避免相应空间图形的交叉和重叠。该图形表示的好处还在于，它仅仅有两种需要计算的可能情况，而在其它的三维表示中，往往有三种需要计算的情况。究其应用，我们对两种可能产生的表示情况，通过计算十二种不同物种间编码序列对应的L/L矩阵产生的正规特征值，构造一个2-维向量来检测上述物种间的相似性与非相似性。