提高企业技术创新能力的主要途径

本文叙述了技术创新与加快信息化建设的意义、相互关系,论述了企业提高创新能力的关键途径是信息化、重要途径是引进外资,阐述了信息化、引进外资对技术创新的重要作用。     

Identification of a LDL-receptor in the lymphatic filarial parasiteWuchereria bancrofti

Little is known about host-parasite inter-relationship in the lymphatic filarial parasites. There is no information available about the ability of these parasites to acquire cholesterol, though it is known that in general, nematodes lack the ability to synthesise cholesterolde novo. In this study, we have shown that the filarial parasites also lack the ability to incorporate labelled acetate into cholesterol, indicating the absence of the machinery for cholesterol biosynthesis. We have further shown that they elaborate a 43 kDa surface receptor for acquiring LDL-bound cholesterol. We have shown by polymerase chain reaction the presence of a 860 bp fragment indicating the presence of the gene for LDL-related protein (LRP) in the human filarial parasiteWuchereria bancrofti in the genomic DNA. We have also shown that it is expressed as seen in the cDNA clones identified from an expression library.     

伊丽莎白政府与尼德兰革命:均势外交政策

本文分三阶段对１５６７—１６０４年间伊丽莎白政府以尼德兰革命为中心而推行的外交政策进行研究,认为这是一种典型的近代均势外交政策,其内容丰富完备,根本目的在于保护英国自身的安全     

分子诊断技术应用于运动分子生物学科研的研究进展

近年来,随着新的分子诊断技术的不断发展,从分子水平上评价运动员在调整期、训练期和比赛期的体质、状态已成为可能.分子诊断技术早在2000年就应用于国内的竞技体育科研中,其主要应用在运动员选材、运动疲劳机理、运动诱导骨骼肌适应、基因治疗技术、基因兴奋剂检测等凡方面.总结了各种新的分子诊断技术在运动分子生物学科研中的应用原理及优缺点,并指出未来其发展方向将侧重于以下几方面:①快速、简便的等位基因检测方法在运动员选材和运动遗传病筛查中的应用;②应用基因技术对运动员选材的地域和种族多态性进行划分;③基因兴奋剂检测技术的革新.     

浅谈影响我国服务贸易竞争力的因素

服务贸易逐渐成为促进国民经济效率提高和国民产出总量增长的主导力量。未来国际市场的竞争将由货物贸易为核心转向以服务贸易为核心,各国服务贸易的竞争实力昭示着其未来对外贸易的前景。     

外文图书采访的传统与网络模式之比较

以POSP为代表的现代网络采访模式克服了传统采访模式的诸多局限,优势明显,但传统模式因其长期沿用的习惯性因素,在现阶段还存在不少可取的合理部分。该文从采访信息源、图书推荐方式、订单制作与发送方式以及采访反馈等方面对二者进行了比较与分析,并指出现阶段高校图书馆应根据本校的实际情况,选择一种为主、另一种为辅的优势互补的采访模式,并应加强网络模式的宣传与推广,以适应未来的发展趋势。     

上海市生物医学外刊资源建设调查与分析

网络环境下,电子期刊大量涌现并越来越受到读者的青睐。近几年,上海市的生物医学外文期刊资源较之以前也渐渐丰富起来,该文调查了2007年上海市引进生物医学外刊的基本情况,介绍了发现的问题并提出了对策。     

国外激光原理经典教材评介与利用研究——以《Lasers》《Laser Fundamentals》《Principles of Lasers》评介为例

为加强国外教材的研究评介和信息服务工作,维护并完善教育部国外教材综合信息平台,推进对国外各学科优秀教材的研究与评介,本课题选定了国外有代表性的、世界著名大学所用的三本激光原理教材作为研究对象。在学习和借鉴发达国家激光原理教材成功经验的基础上,通过深入地分析、研究、比较和归纳总结,对所选三本激光原理经典教材做了客观地评价与介绍,为教育部外国教材的引进与利用提供了重要参考。参考文献17。     

基于基因组方法的虚拟企业组织优化研究

在与一般的组织优化方法比较分析的基础上引入了基因组方法的思想,并给出了具体的实现方法和研究框架.继而初步形成了基于基因组方法的虚拟企业组织优化理论,并对其中的基因重组问题进行了重点研究,由此得出基因重组是实现虚拟企业组织优化有效途径的论断.最后指出:由于可以借助于生物学中的基因重组技术,通过持续地提高"基因"能力要素的竞争能力来实现虚拟企业的组织优化,因而能够较好地解决企业快速响应市场需求变化的问题.     

C677T MTHFR Gene Polymorphism is Contributing Factor in Development of Renal Impairment in Young Hypertensive Patients

Homocysteine concentration affected by the activities of the enzymes methylene tetra-hyrdofolate reductase (MTHFR). Polymorphisms in MTHFR gene associated with an impairment of MTHFR activity. Hyperhomocysteinemia is a result of single nucleotide polymorphisms (SNPs) in MTHFR 677 C>T that can cause homocysteine levels in the blood to increase. The purpose of this study is to investigate the relationships between MTHFR C677T (rs1801133) gene polymorphism, changes in homocysteine concentrations and progress of renal impairment in young adult hypertensive patients. Two hundred young hypertensive patients (age 21–24 years) were involved in this study; they were classified into patients with and without renal impairment in addition to 200 age and sex matched healthy controls. All participants were submitted to laboratory investigations as assay of MTHFR gene polymorphism C677T (rs1801133) by PCR/RFLP, determination of lipid profile, homocysteine and folic acid concentrations in addition to urinary albumin creatinine ratio (UACR). The levels of both homocysteine and UACR in the TT genotype patients were higher than those in the CC genotype group. Individuals who carry the T allele were more risky to hypertension and progress to early renal impairment in young age compared with those carrying the C allele [OR 2.02 (1.33–3.08), P < 0.001]. Genetic variants of C677T MTHFR gene and hyperhomocysteinemia may be responsible for rapid progress of renal impairment in Egyptian young age hypertensive patients. TT genotype or T allele may be considered as a predisposing factor for both elevated Hcy levels and the development of renal impairment. This study believed that lowering of homocysteine level can reduce renal impairment of hypertensive patients.