体育运动中股骨干骨折一例报道

体育运动中股骨干骨折的发生情况并不多见 ,本文报道了一例足球比赛中股骨干骨折的病例 ,并进行了相应的分析和讨论。     

基于椭球面拟合的股骨头修复建模(英文)

提出了一种可以获得目标病例健康时股骨头模型的新建模方法.首先利用一种精确的自动分割方法在髋骨部位CT序列图像中提取髋臼轮廓;然后使用基于等距栅格采样法与辐条式采样法相结合的混合采样法得到髋臼凹面的空间坐标点集,并剔除其中的误差采样点;最后采用基于二次曲面一般方程的方法拟合原始股骨头椭球面模型.通过对2倒不同坏死程度的男性患者进行修复性的对比仿真,以及对50例不同年龄(25～79岁)患者修复重建后的匹配误差统计分析,证明此方法可以良好地还原坏死的股骨头模型,既为骨科临床中的精确手术定位提供了理论模型,又为针对个体化制造的人工假体生产提供了新的实践方法.     

基于ASP的冠状动脉造影及介入治疗管理系统的实现

介绍了在web网络管理平台下应用ASP技术开发冠状动脉及介入治疗管理系统的主要过程，详细介绍了该系统的程序流程和各功能模块的作用，该系统的B／S体系结构和相关的组件技术；重点对应用ASP实现多条件查询、报表生成等关键技术进行了研究．     

Off-pump coronary artery bypass grafting versus on-pumpcoronary artery bypass grafting: which is better in patients with chronic obstructive pulmonary disease?

INTRODUCTION Conventional coronary artery bypass graftin(CCABG) with cardiopulmonary bypass (CPB) habeen accepted as an effective and safe treatment fomulti-vessel coronary heat disease. CPB may stilcontribute to the operation field because of threlatively easier technical requirement; but it alscauses a serious systematic inflammatory reactiowhich will lead to dysfunction of important organand higher cost for the patients. Off-pump coronarartery bypass grafting (OPCABG) has r…     

多元胞结构半导体放电管研制

文章在半导体放电管的版面设计上提出了多元胞结构版图．对多元胞结构“短路模型”进行了理论分析和实验验证．结果表明,合理设计多元胞版图尺寸可以改善器件的转折导通特性,从而为简化半导体放电管生产工艺提供了依据．     

Preliminary studies on serum lipids, apolipoprotein-B and oxidative stress in xanthelasma

Serum lipid profile, apolipoprotein-B (apo-B), malondialdehyde levels(MDA) and superoxide dismutase (SOD) activity were assessed in 12 cases of xanthelasma with and without coronary artery disease (CAD)/hypertension (HTN) and results are compared with healthy controls. Dyslipidemia was found in 65% cases of xanthelasma as compared to 20% healthy controls. Xanthelasma patients had significantly high malondialdehyde (MDA) levels (p<0.01) and significantly decreased (p<0.05) SOD activity as compared to controls. Among xanthelasma patients, xanthelasma with CAD/HTN showed higher total cholesterol (236±32.7 vs 188±24.7 mg/dl), low density lipoprotein cholesterol (157±35.5 vs 113±16 mg/dl) and Apo-B (120.5±9.4 vs 114±19.2 mg/dl) levels as compared to xanthelasma without CAD/HTN. Results of our study indicate that xanthelasma patients with increased apo-B, MDA and decreased SOD need cardiovascular monitoring.     

胰岛素抵抗在糖尿病伴颈动脉粥样硬化形成过程中的作用

目的　探讨老年性糖尿病患者的胰岛素抵抗与颈动脉粥样硬化之间的关系。方法　通过对 42例伴颈动脉粥样硬化的老年糖尿病患者 (CAA组 ) ,40例不伴颈动脉粥样硬化的老年糖尿病患者 (非CAA组 ) ,检测其血浆胰岛素及血糖、血脂等指标并相比较。结果　两组间InS、LDL、CHOL差异有显著性意义 (p <0 0 5 ) ,InS水平与患者LDL、CHOL间存在正相关。结论　HI(高胰岛素血症 )可能通过对糖尿病患者脂质代谢的影响 ,发挥其在动脉粥样硬化形成过程中的作用。     

正常淋浆对大鼠重症休克的干预作用

目的：探讨正常淋浆对肠系膜上动脉闭塞性（SMAO）休克及重症失血性休克的干预作用。方法：雄性Wistar大鼠90只均分为6组，夹闭肠系膜上动脉1h再灌注及颈动脉放血至40mmHg 1h复制SMAO休克和失血性休克模型，分别以小量淋浆及血浆治疗，模型组以等量生理盐水（NS）作对照，观察其血压及存活时间。结果：1．对SMAO休克的影响：淋浆组在休克70～120min血压显著高于模型组（P〈0．05）、在110～120min显著高于血浆组（P〈0．05）．而血浆组与模型组血压未见差异（P〉0．05）；淋浆组3h存活率显著高于其它两组（P〈0．05）。2．对失血性休克的影响：淋浆组输淋浆、输血后期直至停止输液后，血压始终保持在较高水平，且显著高于模型组（P〈0．05～0．01），输NS及停止输液后，血压显著高于血浆组（P〈0．05～0．01）；而血浆组血压仅于输血浆后5～10min高于模型组（P〈0．05）。淋浆组存活时间显著优于其它两组。结论：正常淋浆对SMAO休克及重症失血性休克均具有提升血压及延长存活时间的作用。     

Serum Paraoxonase (PON1) Activity in North-West Indian Punjabi’s with Acute Myocardial Infarction

Human serum paraoxonase-1 (PON1), an enzyme on HDL prevents oxidation of LDL thereby preventing the development of atherosclerosis. Studies done so far have lead to conflicting results. As studies are lacking in North-West Indian Punjabi’s, a distinct ethnic group with high incidence of coronary artery disease, we determined PONase activity in this population. It has been postulated that sudden lowering of serum PONase may lead to precipitation of acute myocardial infarction. We determined serum PONase activity and lipids in 100 patients each of AMI (within 24 h of onset), stable CAD and 100 age and sex matched healthy controls. These were again determined after 6 weeks in AMI patients. The mean serum PONase activity was lowest in AMI patients (23.26 U/ml) followed by stable CAD patients (102.0 U/ml) where as in controls was highest (179.8 U/ml). In patients with AMI, activity was significantly higher at 6 weeks as compared to that after acute event (49.39 %; p < 0.05). Sudden lowering of serum PONase activity in a population which already has lower activity may be one of the risk factors for development of AMI.     

强制性运动疗法及“白脉散”有效成分组对实验性MCAO／R模型神经血管单元细胞凋亡的影响及机制研究

目的：研究强制性运动疗法、“白脉散”抗脑缺血有效成分纽及二者联用对大鼠脑缺血再灌注损伤的保护作用及相关机制。方法：75只雄性SD大鼠随机分为假手术组（Sham）、模型组（MCAO／R）、银杏叶提取物组（EGB）、强制性运动疗法组（CIMT）、“白脉散”有效成分组（ECG）,强制性运动疗法＋“白脉散”有效成分组（CIMT＋ECG）,每组7只。采用线栓法制作大鼠大脑中动脉闭塞再灌注模型,缺血2h再灌注24h后进行神经功能评分,然后ECG组及cIMT＋ECG组以155mg／kg／d灌胃,EGB组以5．6mg／kg／d灌胃,其余组灌胃等体积的溶媒,同时CIMT组及CIMT＋ECG组建立运动疗法模型,每天1次,连续7天。利用免疫组化法观察神经血管单元（NVU）细胞中Bcl-2、Caspase-3蛋白表达的情况,运用原位末端标记（TUNEL）法计数NVU凋亡细胞。结果：CIMT与“白脉散”ECG单独或联合应用可显著改善模型大鼠神经功能评分、抑制NVU细胞凋亡、增加Bcl-2蛋白的表达,降低Caspase-3蛋白的表达。结论：CIMT及“白脉散”ECG可保护MCAO／R模型大鼠神经功能,其机制可能与其抗NVU细胞凋亡,调节凋亡调控因子蛋白表达有关,且二者联用比二者单用具有更佳的保护效果。