透镜成像规律的图象解析

本从透镜成像公式的函数图象，利用数形结合的方法，分析透镜成像规律及其应用。     

Association between TaqIB polymorphism of cholesteryl ester transfer protein and coronary artery disease in the Chinese population

Objective  

To assess whether the TaqIB polymorphism of cholesteryl ester transfer protein (CETP) is associated with coronary artery disease (CAD) in Chinese population, we performed a meta-analysis in this paper.     

Screening for significant atherosclerotic renal artery stenosis with a regression model in patients undergoing transradial coronary angiography/intervention

Objective: Early detection of atherosclerotic renal artery stenosis (ARAS) is clinically important with respect to blood pressure control, prevention of renal insufficiency, and even improving survival. We investigated whether the presence of significant ARAS (luminal diameter narrowing ≥70%) could be predicted using a logistic regression model before coronary angiography/intervention. Methods: Initially, we developed a logistic regression model for detecting significant ARAS based upon clinical and angiographic features and biochemical measurements in a cohort of 1 813 patients undergoing transfemoral coronary and renal angiography. This model was then prospectively applied to an additional 495 patients who received transradial renal angiography to ascertain its predictive accuracy for the presence of significant ARAS. Results: Multivariate regression analysis revealed that older age (≥65 years), resistant hypertension, type 2 diabetes, creatinine clearance (Ccr) ≤60 ml/min, and multivessel coronary disease were independent predictors for significant ARAS. A logistic regression model for detecting ARAS by incorporating conventional risk factors and multivessel coronary disease was generated as: P/(1−P)=exp(−2.618+1.112[age≥65 years]+1.891[resistant hypertension]+0.453[type 2 diabetes]+0.587[Ccr≤60 ml/min]+2.254[multivessel coronary disease]). When this regression model was prospectively applied to the additional 495 patients undergoing transradial coronary and renal angiography, significant ARAS could be detected with a sensitivity of 81.2%, specificity of 88.9%, and positive and negative predictive accuracies of 53.8% and 96.7%, respectively. Conclusions: The logistic regression model generated in this study may be useful for screening for significant ARAS in patients undergoing transradial coronary angiography/intervention.     

有氧运动对力竭过程中大鼠心血管调节因子综合效应及冠状动脉内皮的影响

目的:研究大鼠有氧力竭运动及恢复过程中心血管调节因子综合效应和冠状动脉内皮功能的变化,以期探索运动性疲劳发生的生理学机制。方法:将60只雄性Wistar大鼠随机分为:对照组、运动1 h组、运动3h组、力竭组、力竭恢复2h组、力竭恢复12h组。每组大鼠进行8周跑台训练后,分别于各组对应时刻处死,取血浆测定各组大鼠NO、ET、ANP、TXB2含量,扫描电镜观察冠状动脉内皮。结果:运动1h组NO/ET比值极显著性高于对照组(P<0.01),运动3h组和力竭组显著性低于对照组(P<0.05);运动3h组和力竭恢复2h组大鼠血浆中ANP含量极显著高于对照组(P<0.01),力竭组显著高于对照组(P<0.05);运动3h组、力竭组和力竭恢复2h组血浆TXB2浓度显著高于对照组(P<0.05);运动3h组、力竭组和力竭恢复2 h组大鼠冠状动脉内皮均出现Ⅲ级损伤。结论:1)运动初期心肌供血、供氧能力与运动强度相适应。2)心血管调节因子综合效应变化导致冠状循环供血/供氧不足可能是运动性疲劳的原因。     

长期大运动量耐力训练对SD大鼠肾动脉张开角影响的研究

通过观察肾动脉主干张开角的大小,研究了经过长期大强度耐力训练的SD大鼠肾动脉主干零应力状态的变化.结果发现,经过长期耐力训练的SD大鼠的肾动脉主干的张开角(70.12°±5.83°)显著小于同龄的安静对照组的大鼠的肾动脉主干的张开角(79.47°±6.89°).结果表明,在长期耐力训练组中,大鼠肾动脉主干存在非均匀的负生长,其残余应力、应变小于同龄的安静对照组大鼠的肾动脉.因此,长期耐力训练会导致肾动脉主干的负生长,可能对肾动脉的生理功能产生一定的影响.     

椎动脉型颈椎病的临床治疗

对椎动脉型颈椎病的病因发病机理进行了解剖学分析,结合临床实践探讨治疗方法.     

经皮子宫动脉栓塞术治疗子宫肌瘤78例疗效观察

目的观察子宫动脉栓塞术治疗子宫肌瘤的疗效。方法采用seldinger’s方法作选择性子宫动脉栓塞。结果双侧子宫动脉栓塞可完全阻断子宫肌瘤血供。治疗后随访结果表明,肌瘤均比治疗前缩小,月经周期恢复正常,经量增多、贫血症状均明显改善,总有效率达100%。结论子宫动脉栓塞术治疗子宫肌瘤创伤小,并发症少,治疗效果好,是值得推广应用的好方法。     

Assessment of internal mammary artery injury after blunt chest trauma: a literature review

The occurrence, bleeding, and treatment of internal mammary artery (IMA) injury after blunt chest trauma have not been well described in the literature. We reviewed articles published from July 1977 to February 2014 describing IMA injury after blunt chest trauma in 49 patients. There was a predominant incidence in males and on the left side. Blunt trauma to the IMA can cause anterior mediastinal hematoma, hemothorax, pseudoaneurysm, arteriovenous fistula, and extra-pleural hematoma. Of the 49 patients studied, 20 underwent embolization, 22 underwent surgical operation, 4 were managed by clinical observation, and 3 had undescribed treatment. Different parts and extents of IMA injury, adjacent vein injury, as well as the integrity of the pleura determined differences in bleeding modality. Prompt diagnosis, complete hemostasis, aggressive resuscitation, and multidisciplinary teams are recommended for patients with IMA injury.     

祁山道、卤城：陇蜀互动之交通要道与战略支点

“蜀道”不应单指连接关中平原和成都平原的川陕道路,还应包括自陇（甘肃）入川的陇蜀道路,唯有如此,“蜀道”才属完整概念。甘肃陇南地区是陇蜀道必经的核心区域。陇右天水经祁山道、卤城可抵汉中至川蜀,也可抵武都,再经文县（阴平道）入川蜀。无论秦汉时期、三国时期,还是宋金时期,祁山道都为陕甘川三省经济、文化、军事交流与互动提供了极为重要的交通条件;而卤城也因其重要的地理位置和独特的盐业资源成为祁山道上一座历史文化名镇。     

Somatic DNA Damages in Cardiovascular Autonomic Neuropathy

Cardiovascular autonomic neuropathy (CAN) is one of the most clinically significant complications of diabetes mellitus. Even though many ethological factors have been attributed for the pathogenesis of this disease no attempts were made to correlate DNA damage as a causative factor. Hence the present study was undertaken to asses the extent of somatic DNA damages by cytokinesis-block micronuclei assay (CBMN). An attempt is also being made to correlate the habits and/or risk factors and socioeconomic status with CAN. The CBMN frequency of 46 patients suffering from autonomic neuropathy was compared with that of 25 healthy age and sex matched controls. All the subjects were suffering from type 2 diabetes for at least 8 years and have varying degrees of coronary artery diseases. The mean CBMN frequency of the patients was statistically higher than that of the healthy control subjects (P < 0.05). The CBMN frequency was found to be significantly altered in CAN patients who where physical inactivity and smoking. A significant correlation could also be observed between CAN and smoking, diabetes mellitus, hypertension, dyslipidemia, abdominal obesity, and physical activity.