2003~2013年中国城市休闲化质量评估——耦合与协调双重视角的考察

基于耦合与协调双重视角,通过构建指标体系和评估模型,采集2003~2013年中国36座城市数据,全面考察和评估中国城市休闲化质量,并进行空间差异特征分析.研究发现:①中国城市休闲化耦合发展处于拮抗阶段,并快速向磨合阶段迈进;②目前中国城市休闲化协调发展水平相对较低,但呈现出持续提升态势,同时城市间差距较大;③东部和西部城市休闲化耦合度相对较高,而协调度大致呈现由东向西依次递减的趋势.     

函数的微分与积分——广义实数应用

使用广义实数解释了一元实函数微分的本质,并给出了牛顿-莱布尼兹公式的简单证明．     

克拉克·克尔的精英高等教育思想及其启示

克拉克·克尔认为,精英高等教育与大众化高等教育在价值取向、招生和课程管理等方面与大众化高等教育有显著不同。大众化高等教育未必是精英高等教育的敌人,它可能对精英高等教育产生冲击与破坏,但是只要不同高等院校的职能合理分化,并在不同类型的院校之间建立起沟通的桥梁,大众化高等教育的发展对精英高等教育有保护作用。克拉克·克尔的这些思想对我国当前正确处理精英高等教育与大众化高等教育的关系,保护精英高等教育发展有重要启示。     

充分发挥“精讲多练”在语文自主学习中的优势

分析普通中学语文教学“填鸭式”教学的几种弊端,论述“精讲多练”的好处,认为要真正达到语文教学的目的,就必须改变过去陈旧的教学方法,努力做到有的放矢,精讲多练,自主互动,使学生在语文学习中有所收获,提高能力。     

庄子《齐物论》思想研究

通过对庄子的“齐物论”含义争论的分析,指出庄子的用意在于“使万物齐”而不是“齐各家之言论”,认为《齐物论》中所指的世俗世界是“有分别”的世界,而庄子则致力于破除这种分别;在庄子的视野中,“物化”的境界是介于“有分别”的凡俗世界和“道通为一”的境界之间的。     

基于生物免疫学原理的海西城市群土地综合承载力研究

本文根据免疫学原理,从土地承载力(包括天然的、获得性的)和人口社会经济发展压力两个方面构建综合评价指标体系,将生物免疫学模型进行修正后与状态空间模型相结合,以海峡西岸城市群为例,对2006-2012年期间土地综合承载力时空分异特征及可持续发展状态进行综合测评。研究表明:在2006-2012年期间,承载力和压力二者的变化趋势夹角总体上由正转负,可持续发展趋势不太乐观;对2006年、2012年两个评价时点承载潜力对比分析发现,初步判断为超载的面积比重由72.9%扩大到90.3%,承载潜力内部差距正在逐渐拉近,承载潜力空间上均呈现“总体沿海高于内陆,局部山区和发展节点较低”的分布特征,与海峡西岸城市群的地势、开发密度的空间格局密切相关;未来应通过提高资源利用效率、改变发展方式等来调节承载力与压力之间的平衡,并重视引导各类社会经济要素在空间上的科学合理分布来促进城市群内部协调发展。     

Preparing beginning teachers for inclusion: designing and assessing supplementary fieldwork experiences

Inclusive education requires restructuring educational provision so that mainstream schools are able to provide for the needs of all students in their communities. To help realise this goal, initial teacher education programmes need to better prepare new graduates for teaching students with complex special education needs, including students with intellectual disability. Concerns about the capacity of current school-based placements to prepare new teachers for inclusive classrooms have led some teacher education institutions to develop supplementary fieldwork experiences. The current study involved an investigation into such an experience and looked at the benefits to pre-service teachers (PSTs) of tutoring a young adult with intellectual disability. The findings indicate that PSTs learned effective strategies for differentiating a programme of work and, in their first year of study, were developing a teacher identity. The importance of aligning experiences with coursework units is highlighted and the need for valid assessments of how well initial teacher education programmes are preparing beginning teachers for inclusion, and what these assessments may look like, is discussed.     

国内外企业研发投入差异化激励政策研究

梳理近期国内外实施的企业研发投入差异化激励政策,提出完善我国企业研发投入财税激励政策的对策建议。     

Case Report: CD19-positive acute myeloblastic leukemia with trisomy 21 as a sole acquired karyotypic abnormality

We report that a 63-year-old Chinese female had acute myeloblastic leukemia (AML) in which trisomy 21 (+21) was found as the sole acquired karyotypic abnormality. The blasts were positive for myeloperoxidase, and the immunophenotype was positive for cluster of differentiation 19 (CDI9), CD33, CD34, and human leukocyte antigens (HLA)-DR. The chromosomal analysis of bone marrow showed 47,XX,+21 [2]/46,XX[18]. Fluorescent in situ hybridization (FISH) showed that three copies of AML1 were situated in separate chromosomes, and that t(8;21) was negative. The patient did not have any features of Down syndrome. A diagnosis of CD19-positive AML-M5 was established with trisomy 21 as a sole acquired karyotypic abnormality. The patient did not respond well to chemotherapy and died three months after the diagnosis. This is the first reported case of CD19-positive AM L with trisomy 21 as the sole cytogenetic abnormality. The possible prognostic significance of the finding in AML with +21 as the sole acquired karyotypic abnormality was discussed.     

CD19-positive acute myeloblastic leukemia with trisomy 21 as a sole acquired karyotypic abnormality

We report that a 63-year-old Chinese female had acute myeloblastic leukemia (AML) in which trisomy 21 (+21) was found as the sole acquired karyotypic abnormality. The blasts were positive for myeloperoxidase, and the immunophenotype was positive for cluster of differentiation 19 (CD19), CD33, CD34, and human leukocyte antigens (HLA)-DR. The chromosomal analysis of bone marrow showed 47,XX,+21[2]/46,XX[18]. Fluorescent in situ hybridization (FISH) showed that three copies of AML1 were situated in separate chromosomes, and that t(8;21) was negative. The patient did not have any features of Down syndrome. A diagnosis of CD19-positive AML-M5 was established with trisomy 21 as a sole acquired karyotypic abnormality. The patient did not respond well to chemotherapy and died three months after the diagnosis. This is the first reported case of CD19-positive AML with trisomy 21 as the sole cytogenetic abnormality. The possible prognostic significance of the finding in AML with +21 as the sole acquired karyotypic abnormality was discussed.