High-intensity focused ultrasound with large scale spherical phased array for the ablation of deep tumors

et tissue by either moving single focal point or generating multiple loci simultaneously.     

A correlation between acute kidney injury and myonecrosis after scheduled percutaneous coronary intervention

Slight elevations in cardiac troponin I and T are frequently observed after percutaneous coronary intervention (PCI). Contrast-induced acute kidney injury (CI-AKI) is a complex syndrome induced by exposure to intravascular contrast media (CM). Currently, the relationships between the CM, pre-existing kidney insufficiency, CI-AKI, and myonecrosis after elective PCI are unclear. To investigate the relationship between CI-AKI and post-procedural myonecrosis (PMN) after PCI, we analyzed 327 non-ST-segment elevation acute coronary syndrome subjects undertaking elective PCI. The levels of cardiac troponins (cTns), cTnI and cTnT, at baseline and on at least one occasion 18–24 h after PCI were measured. We also recorded serum levels of creatinine (SCr) and the urine albumin:creatinine ratio (ACR) before coronary angiography, and 24–48 h and 48–72 h after contrast administration. A post-procedure increase in cTns was detected in 16.21% (53/327) of subjects with cTns levels >99th to 599th percentile upper reference limit (URL). Twenty-seven patients (8.26%) developed CI-AKI. CI-AKI occurred more often in subjects with PMN than in those without PMN (20.8% versus 5.8%, respectively, P=0.001). Multiple logistic regression analysis revealed that pre-existing microalbuminuria (MA) was an important independent predictor of PMN (OR: 3.31; 95% CI: 1.26–8.65, P=0.01). However, there was no correlation between the incidence of CI-AKI and PMN (OR: 2.38; 95% CI: 0.88–6.46, P=0.09). We conclude that pre-existing MA was not only an important independent predictor of CI-AKI but also of PMN.     

Scanning electron microscope hypsometry as a tool for evaluating the impact of surface treatments: A case study on sub-fossil bone

Abstract

Plaster of Paris field jackets are commonly employed for lifting fragile archeological and paleontological material during excavation. When the plaster has been applied directly to the object surface its removal poses a severe risk of damage and loss. This study documents the development of an experimental method to test the suitability of various techniques for removing plaster of Paris from sub-fossil bone. The use of digital microscopic elevation models, already in use in other disciplines, was tested as a method for quantifying surface loss resulting from conservation treatments. The study concludes that citric acid is not suitable for use in close proximity to sub-fossil bone. Air abrasion and laser ablation proved extremely damaging, but ultrasonic cleaning caused no detectable damage. This study has relevance to the removal of plaster of Paris from other materials, such as carbonaceous statuary. The analytical technique itself has a far wider application and is recommended for evaluation of all surface treatments that have the potential to cause loss on a microscopic scale.     

Application of GlycoProtein IIb/IIIa antagonist( Integrilin) in peri-percutaneous transluminal catheter angioplasty and stent implantation in Chinese

Objective: to report the application of GPIIb/IIIa antagonist (Integrilin) in peri-percutaneous transluminal catheter angioplasty and stent implantation in Chinese. Method: Twenty-one patients who underwent percutaneous transluminal catheter angioplasty(PTCA) and stent implantation were included. After arterial puncture, integrilin was injected at dose of 180ug/kg, and then maintained at 2μg/kgmin for 18 hours. Asprine, plavix(clopidogrel) and heparin were used at the same time. ACT, PT, KPTT and blood routine were routinely monitored. Results: All sheaths were drawn out 2 to 4 hours after the procedure.. There was no severe complication such as hematoma, acute and subacute thrombosis in coronary artery, or thrombocytopenia. ACT returned to less than 150 seconds in 2 hours in 15 patients; in 4 hours in 6 patients. There was no significant difference between the pre- and post-procedure value of PT and platelet count. KPTT was significantly higher than pre-procedure value at 2 hours after the procedure .No recurrence of angina pectoris was observed in the first nine patients within one year follow-up, and no restenosis occurred in stents in the five patients who had coronary angiography one year later. Conclusion: Application of GPIIb/IIIa receptor antagonist (Integrilin) in peri-percutaneous transluminal catheter angioplasty and stent implantation in combination with aspirin and plavix could significantly reduce the dosage and duration of heparin with benefit of shortening the indwelling time of sheaths, but did not increase risk of bleeding or lead to thrombosis in stent.     

激光轰击制备碳纳米管及其相关纳米材料

采用Nd：YAG脉冲激光在常温常压下轰击浸于乙醇流动相中的铁／石墨混合靶进行制备碳纳米管的研究。用傅立叶红外光谱、X射线衍射和透射电镜等现代分析技术分别对激光轰击所得产物进行表征。结果表明，以铁为催化剂，激光波长为1064nm，激光功率密度为4．5x10^9W/cm^2的条件下可成功制备碳纳米管，并且，透射电镜观察到所得的碳纳米管管径约为20～50nm，长度约几百nm，最长可达1μm以上。     

经皮冠状动脉介入术后护理进展

文章从经皮冠状动脉治疗(PCI)的相关知识、术后的一般护理、病情观察、拔除鞘管的护理、抗凝治疗护理、并发症的预防、心理护理及康复指导方面对经皮冠状动脉介入术后的护理进展进行了综述。     

Current status of percutaneous coronary intervention of chronic total occlusion

This paper describes the current status of percutaneous coronary intervention (PCI) for totally occluded coronary arteries. Chronic total occlusion is associated with 10%–20% of all PCI procedures. Results show that opening an occluded vessel, especially one supplying a considerable area of myocardium, may be beneficial for a patient’s angina relief and heart function. We describe the devices used currently in re-canalization such as new wires, microcatheters (including Tonus and Cosair) and intravascular ultrasound guidance. Different techniques to improve the success rate and reduce complications are discussed in detail.     

Ultrasound ablation of pulmonary veins for treatment of paroxysmal atrial fibrillation

Objective: to evaluate the efficacy and safety of ultrasound ablation of pulmonary veins for treatment of paroxysmal atrial fibrillation. Methods: The study population consisted of 9 patients with 5 males and 4 females enrolled consecutively who had idiopathic paroxysmal atrial fibrillation(AF). The ultrasound balloon was positioned through a special sheath to the orifice of the target vein by a transseptal procedure. The balloon was inflated with contrast-mixed saline (contrast: saline = 1:4) whose volume was decided by the diameter of the target pulmonary vein. The ablation energy was usually set up at 35 to 40 watts with temperature controlled at 60℃. The duration of each ablation was about 120 seconds which was repeated not over 10 times. Results: The average duration of the total procedure was 132±68 min for our patients. The average fluoroscopy time was 33±17 min. With a mean follow-up of 16±8 months after the procedure, AF was completely eliminated in 4 patients without antiarrhythmic drugs. The episodes of atrial fibrillation were eliminated in 2 patients with low dosage of oral amiodarone (0.1, once daily) which was ineffective before the procedure. The frequency of episodes was similar to that before the procedure in 3 patients. There were no complications such as hemopericardium, air embolism and stenosis of the pulmonary veins by angiography, related to the procedure. Conclusion: Ultrasound ablation of the pulmonary veins is a new approach to treat paroxysmal atrial fibrillation. Before we determined its value, we need to do more researches with bigger sample, randomization and comparison design.     

脱醇双组分室温硫化硅橡胶“耐烧蚀“性的研究

本文探讨了几种影响模具胶耐烧蚀性的因素。排除了107胶和硅油分子量的影响因素,提出了某些填充料可以对提高模具胶的耐烧蚀性有所帮助,同时还根据硅橡胶的耐热机理选择了几种耐烧助剂应用于模具胶,取得了明显的耐烧蚀效果。