速效记忆英语三级词汇 促进学生英语水平的提高

本文从高职英语教育的现状出发,分析原因,得出词汇记忆的重要性,并尝试提出了几种词汇记忆的方法,希望可以对学生学习英语起到很好的帮助作用。     

高级酒店中层管理人员素质测评探究

依据人员素质测评的理论,通过对高级酒店中层管理人员的工作分析,进而建立其素质测评的指标体系结构,并通过层次分析法确定其权重,以做到对高级酒店中层管理人员素质的科学测评。     

技术就绪度方法在国家科技计划项目评估中的应用

在当前我国科技成果转换率低下、研发成果稳定性与可靠性普遍不足的情况下,技术就绪度方法为管理部门提供了行之有效的管理和评估工具。首先对技术就绪度发展及应用情况进行调研,在此基础上对该方法在国家仪器专项项目中期评估中的应用进行总结分析。实践表明,技术就绪度方法对重大共性关键技术和应用示范类的国家科技计划项目评估具有适用性,可以对项目管理决策、质量控制、风险防控等发挥重要作用。     

应对气候变化科技综合定量评价方法研究

气候变化是当今国际社会的重要议题,其中科技创新是应对气候变化行动中的重要抓手。本文基于技术就绪度评价的标准化理念,从项目关键技术的成熟性、对气候的需求度、以及技术难度等角度,研究评价R&D项目对气候变化影响的评价方法,并给出评价细则。     

我国《普通高等学校招收高水平运动员办法》修订研究

《普通高等学校招收高水平运动员办法》的颁布实施,为我国竞技体育体制改革作出了极为重要的探索,然而其在运行中也出现了诸如学训矛盾、运动员成材率低等不少问题,为促进高校办高水平运动队制度的发展,应当对这一文件作出修订,以促进我国竞技体育＂院校化＂模式的完善。     

RBC membrane composition in insulin dependent diabetes mellitus in context of oxidative stress

Glyco-oxidation is considered as a source of permanent, cumulative, oxidative damage to long lived proteins in ageing and in diabetes. Although RBC depends solely on glucose for energy purpose, hyperglycemic state glycosylates hemoglobin, creates oxidative stress and puts the cellular components at risk. In view of this, RBC membrane composition was analyzed in diabetic patients. The results were compared with healthy age and sex matched control groups. When RBC membrane components such as protein, sialic acid, phospholipids and cholesterol were determined in insulin dependent diabetes mellitus, a significant rise in phospholipids and cholesterol and significant fall in sialic acid and protein content was noted. RBC membrane composition showed pronounced alterations in insulin dependent diabetes mellitus. These changes were accompanied by higher levels of lipid peroxidation products like Malondialdehyde.     

四种单细胞藻类营养价值的研究

本文利用扫描电镜Ｘ－射线能谱分析议,对四种单细胞澡类细胞内含有的元素种类进行了分析,它们都含有Ｋ、Ｎａ、Ｃａ、Ｍｇ、Ａｌ、Ｐ、Ｓ等元素。同时,使用了化学法分析了这些藻类的氨基酸、蛋白质、多糖、糖醛酸等含量     

对我国运动员50年代以来膳食热源质比例分析

我国运动员在膳食结构中长期地存在着不合理现象,且有随着年代的推进日趋严重的趋势。据此提出若干改进意见,以便使我国运动员在膳食结构中,三大热源质摄入比例合理化     

江苏县域教育现代化建设与评估的实践

江苏是在全国较早提出要率先基本实现教育现代化目标的省份,从面向教育现代化的理念、目标、内涵到建设教育现代化的行动、指标、评估,江苏在强化顶层设计、注重标准引领、创新评估机制、坚持评建结合等方面进行了深入的实践探索,取得了显著的成效,全省区域教育现代化建设呈现新的面貌和格局,开辟了一条县域范围实现教育科学发展、快速提升教育现代化水平的崭新道路,探索了一个建设标准为导向、水平评估为杠杆、表彰奖励和满意度调查为强大推力的教育现代化工作机制,创新了一套县域教育评价规范评估、阳光评估、和谐评估科学运行的操作范式。     

Effect of Palrnatine on lipopolysaccharide-induced acute lung injury by inhibiting activation of the Akt/NF‍-κB pathway

Inflammation plays an important role in the development of acute lung injury (ALI). Severe pulmonary inflammation can cause acute respiratory distress syndrome (ARDS) or even death. Expression of proinflammatory interleukin-‍1β (IL-‍1β) and inducible nitric oxide synthase (iNOS) in the process of pulmonary inflammation will further exacerbate the severity of ALI. The purpose of this study was to explore the effect of Palrnatine (Pa) on lipopolysaccharide (LPS)-induced mouse ALI and its underlying mechanism. Pa, a natural product, has a wide range of pharmacological activities with the potential to protect against lung injury. Western blotting and quantitative real-time polymerase chain reaction (qRT-PCR) assays were performed to detect the expression and translation of inflammatory genes and proteins in vitro and in vivo. Immunoprecipitation was used to detect the degree of P65 translocation into the nucleus. We also used molecular modeling to further clarify the mechanism of action. The results showed that Pa pretreatment could significantly inhibit the expression and secretion of the inflammatory cytokine IL-1β, and significantly reduce the protein level of the proinflammatory protease iNOS, in both in vivo and in vitro models induced by LPS. Further mechanism studies showed that Pa could significantly inhibit the activation of the protein kinase B (Akt)/nuclear factor-κB (NF-κB) signaling pathway in the LPS-induced ALI mode and in LPS-induced RAW264.7 cells. Through molecular dynamics simulation, we observed that Pa was bound to the catalytic pocket of Akt and effectively inhibited the biological activity of Akt. These results indicated that Pa significantly relieves LPS-induced ALI by activating the Akt/NF-κB signaling pathway.