高师本科化学专业教学计划修订的实践与思考

从培养21世纪人才的高度，对高师本科化学专业教学计划进行修订，提供新教学计划的课程设置模式，有利于促进新教材编写，师资队伍建设和教育科研的进一步开展。     

有机化学实验考核方法的改革和探索

通过对传统有机化学实验考核方法弊端的分析,阐述了改革传统考核方法的必要性,建立了新的考核方法,设计了有机化学实验考核评估指标体系,并将评估指标转化为可操作的教学行为,促进了教与学,做到了全方位、客观地评价学生的实验课成绩。     

以情感互动为平台,构建和谐化学课堂

目前学生在课堂教学上缺乏创造力得以发展的学习空间,缺乏一种关系和谐、能力发展的教学氛围。从教学心理、氛围、行为、评价四个方面论述了构建和谐化学课堂的一些措施。     

在化学教学中渗透环保教育

环境保护是我国的基本国策,环保教育是中学教学的重要任务.从环保教育的重要性、紧迫性入手,提出当务之急在于构建完备的中学化学环保教育方案,从教材内容、化学实验等方面渗透环保教育进行阐述,使学生树立起环保意识.     

雨课堂辅助物理化学实验教学方法探讨

物理化学实验是化学类专业大学教育的重要组成部分。为提高教学质量,我们采用雨课堂辅助实验教学,以解决目前物理化学实验教学中存在的问题,进而改革教学模式,优化考核方式,使其在创新性人才培养中发挥重要作用。     

Student Perceptions of Chemistry Laboratory Learning Environments, Student–Teacher Interactions and Attitudes in Secondary School Gifted Education Classes in Singapore

This study investigated the chemistry laboratory classroom environment, teacher–student interactions and student attitudes towards chemistry among 497 gifted and non-gifted secondary-school students in Singapore. The data were collected using the 35-item Chemistry Laboratory Environment Inventory (CLEI), the 48-item Questionnaire on Teacher Interaction (QTI) and the 30-item Questionnaire on Chemistry-Related Attitudes (QOCRA). Results supported the validity and reliability of the CLEI and QTI for this sample. Stream (gifted versus non-gifted) and gender differences were found in actual and preferred chemistry laboratory classroom environments and teacher–student interactions. Some statistically significant associations of modest magnitude were found between students' attitudes towards chemistry and both the laboratory classroom environment and the interpersonal behaviour of chemistry teachers. Suggestions for improving chemistry laboratory classroom environments and the teacher–student interactions for gifted students are provided.     

荧光标记法检测活细胞内游离钙离子浓度的改进

改进了活细胞内游离钙离子浓度的测定方法，即用惰性基体纳米微球包埋荧光染料，将荧光纳米微球转运进细胞，用于细胞内游离钙离子浓度的实时测定。该方法与传统方法相比，染料不易泄漏，不会出现分室现象，不易光漂白，是一种非常有实用价值的测量活细胞内游离钙离子浓度的方法。     

La掺杂Co-Fe-O纳米磁性材料的制备和表征

以Fe(NO3)3·9H2O,Co(NO3)2·6H2O和La2O3为原料,首先制备出晶粒细小的盐渍化碱式碳酸盐前驱体,在400℃、500℃、600℃、700℃、800℃分别烧结1h,制备出CoFe2O4和LaCo0.4Fe0.6O3纳米磁性材料,并用XRD、SEM和IR对样品进行表征,研究了不同的烧结温度和La掺杂对物相的形成及颗粒大小的影响.     

Microwave-assisted synthesis, anticonvulsant activity and quantum mechanical modelling of N-（4-bromo-3-methylphenyl） semicarbazones

Objective： To study the effect of halo substitution on disubstituted aryl semicarbazones on the anticonvulsant potential and model the activity based on quantum mechanics. Methods： A series of twenty-six compounds of N^4-（4-bromo-3-methylphenyl） semicarbazones were synthesized and evaluated for the anticonvulsant activity in the maximal electroshock seizure （MES） and subcutaneous pentylenetetrazole （scPTZ） seizure threshold tests. Some potential compounds were also tested in the subcutaneous strychnine （scSTY） and subcutaneous picrotoxin （scPIC） seizure threshold tests. The synthesized compounds were tested for behavioral impairment and CNS （central nervous system） depression in mice. Quantum mechanical modelling was carried out on these compounds to gain understanding on the structural features essential for activity. Results： Some compounds possessed broad spectrum anticonvulsant activity as indicated by their effect in pentylenetetrazole, strychnine, picrotoxin and maximal electroshock seizures models in resemblance to other aryl semicarbazone derivatives reported earlier. The higher the difference in HOMO （highest occupied molecular orbital） and LUMO （lowest unoccupied molecular orbital） energy levels was, the greater was the activity profile. Conclusion： The pharmacophoric requirements for compounds to exhibit anticonvulsant activity that includes one aryl unit in proximity to a hydrogen donor-acceptor domain and an electron donor have been justified with the molecular orbital surface analysis of the synthesized compounds.     

物理化学实验教学的探索与实践

针对目前物理化学实验教学中普遍存在的问题,提出了一些改进实验教学的方案,并付诸实践。