高效毛细管电泳法研究β-淀粉样蛋白与金属离子的相互作用

β-淀粉样蛋白(Aβ)的聚集及纤维生成与阿尔茨海默病(AD)存在密切的关系,大量证据表明,老年斑中含有高浓度的过渡金属离子如Zn²⁺、Cu²⁺和Fe³⁺. 本文采用高效毛细管电泳法(HPCE-UV)研究金属离子与Aβ16以及Aβ28的相互作用. 研究表明,Zn²⁺、Cu²⁺和Fe³⁺都可以与Aβ发生相互作用,但Cu²⁺可以诱导Aβ16的聚集生成低聚体而Zn²⁺不能. Zn²⁺和Fe³⁺都可以诱导Aβ28生成低聚体,但聚集的速率不同.     

基于三维重建的分布式卫星SAR干涉测高模型及误差分析

基于InSAR目标三维重建原理对分布式卫星SAR干涉测高系统模型及工作原理进行了分析,给出了完整的目标位置三维重建闭合形式解;并对影响三维重建精度的主要误差源——基线矢量误差和干涉相位误差进行了详细分析;最后通过仿真分析了基线矢量误差和干涉相位误差特性,从而为系统参量定标及其校正提供了基础.     

阵列天线微波成像多通道相位误差校正方法

采用阵列天线的微波成像系统会产生多通道幅相不一致性问题.针对使用阵列天线进行微波成像的应用,将回波模型中的多通道相位误差分为距离偏移误差和残余常数相位误差,并分析其对成像造成的影响,研究了使用回波中选定参考点目标进行相位误差校正的方法.最后通过微波成像国家重点实验室开发的地基实验系统数据验证了我们的分析和结论.     

以粒子蜂群网络建立高性能混凝土坍落度模型

以粒子蜂群算法(particle bee algorithm, PBA)结合神经网络(artificial neural network, NN),发展出一套能预测高性能混凝土(high performance concrete, HPC)坍落度模型的方法。以演化运算树(genetic operation tree, GOT)及倒传递网络(back propagation network, BPN)2种已发表的方法来比较其准确度。从模型的准确度可知,粒子蜂群网络(particle bee neural network, PBNN)模型预测的准确度高于GOT,但接近BPN的准确度;从参数的影响性可知,PBNN显示水、强塑剂、粗骨材、细骨材、粉煤灰及水泥添加量对于HPC坍落度的影响性大,而高炉矿渣粉用量对HPC坍落度并不敏感,显示各项材料对于坍落度的影响仍具备高度复杂性。     

太极推手技法的哲理诠释

太极推手是太极拳文化重要的组成部分。对太极拳的研究不能遗忘对太极推手的研究。也因此,对太极推手的文化技术研究显得弥足珍贵。通过文献资料的查阅,在研读太极拳古籍文本的基础上,运用哲学思辩的理论和方法,对太极推手技术理论进行归纳分析。研究认为,太极推手技理的哲学意义表现为：沾粘连随求得机得势;引化拿发达以柔克刚;刚柔并济显以巧斗力;舍己从人示和谐向善。文章最后指出,在太极推手技法体系中,各个环节是一个统一的有机体,沾粘连随是基础,引化拿发是表现,刚柔并济是手段,舍己从人是目标。     

Physical education teaching as a caring act—techniques of bodily touch and the paradox of caring

In this article, we investigate ‘no touch policies’ as a practical teacher concern that includes the body as a location, a source and a means in educational activity. We argue that to understand issues regarding physical touch within school practice we must conceive it as deeply associated with specific teaching techniques. Thus, the didactical challenge is not found in argumentations about the pro and cons of physical touch, but through analysis of how teachers handle student interaction and teaching intentions.

We consider teaching as a caring profession. Caring, as a practical teacher concern, requires wisdom regarding the right time to use bodily touch and to refrain from such use. This wisdom involves the ability to discern people’s needs, desires, interests and purposes in particular situations and act appropriately. From a body pedagogical perspective we approach intergenerational touch not only as a discursive and power-related question but as an essential tension in the intersection of the; ambiguity attendant to any intentional act such as teaching, the conflict between the ethics of care and the ethics of justice, and finally, the paradox of caring.

We draw on interviews with PE-teachers in Swedish primary, secondary and upper-secondary schools and analyses of a collection of techniques of bodily touch that are established and practiced with specific pedagogical purposes. The results shows PE teacher’s competence in handling different functions of intergenerational touch in relation to three different techniques of bodily touch; (1) Security touch, which is characterized by intentions to handle the fragile; (2) Denoting touch, which is characterized by intentions to handle learning content and (3) Relational touch, which is characterized by caring intentions. Each of these is of importance for the teachers in carrying out their call to teach and each of these relies on professional assessments whether or not it meets its intended purpose.     

Kinematic comparison of the seoi-nage judo technique between elite and college athletes

This study sought to identify biomechanical factors that determine fast and skilful execution of the seoi-nage (shoulder throw) technique by comparing kinematics between elite and college judo athletes. Three-dimensional motion data were captured using a VICON-MX system with 18 cameras operating at 250 Hz as three male elite and seven male college judo athletes performed seoi-nage. No significant difference was found in motion phase time of the turning phase between the two groups, indicating that motion phase time is not necessarily a factor contributing quickness in seoi-nage. The maximum relative velocity of the whole body centre of mass along the anterior–posterior direction was significantly greater in the elite athletes (2.74 ± 0.33 m/s) than in the college athletes (1.62 ± 0.47 m/s) during the turning phase (p = 0.023). The overall angular velocity of the body part lines, particularly the arm line, tended to be greater in the elite athletes (p = 0.068). The results imply that the velocity of the thrower relative to the opponent in the forward drive and turning motion reflects high skill seoi-nage. Coaches should recognise the relative forward velocity as a factor that may contribute to a successful seoi-nage when teaching the judo throw technique.     

Does local dynamic stability of kayak paddling technique affect the sports performance? A pilot study

During competition, kayak athletes must optimally adapt to environmental factors (e.g. wind, waves) to achieve peak performance. However, the ability to adapt to such perturbations has never been assessed in kayak paddling. Therefore, the aim of the current study was to evaluate the local dynamic stability in sports technique of youth sprint kayak athletes. In a cross-sectional study, 14 healthy male athletes were recruited from an elite youth sprint kayak squad. During an incremental kayak ergometer test, mean power, heart rates and local dynamic technique stability of hands, arms, trunk and paddle were registered and the association with the athletes 2000?m free-water times were estimated using mixed models. The 2000?m free-water performance significantly predicted the paddles (p?=?.037) local dynamic stability whereas no association was found for the trunk or the upper extremity kinematics. In conclusion, kayak athletes with high-performance capability over 2000?m paddling depict high local dynamic technique stability. This emphasizes the importance of a stable technique for advanced kayak skills, especially regarding paddling movements.     

The timing and critical incident of epistemic beliefs change in Hong Kong college students: an exploratory study

Research on epistemic beliefs (beliefs about what knowledge is and what knowing is) has advanced and there is now a burgeoning interest in examining this construct in the Chinese cultural context. However, issues related to understanding epistemic beliefs change remain under-explored. The present study used a qualitative approach to explore Chinese college students’ timing and critical incidents of epistemic beliefs change. Eight college students from Hong Kong participated in interviews and three key themes emerged from their responses. First, students identified college transition as a major source of epistemic perturbation. Second, they attributed epistemic beliefs change mostly to educational encounters. These encounters were characterized by a curriculum with multiple perspectives, being taught by teachers who could provide cognitive scaffolding for epistemic belief resolution, and assessment processes that allowed the latitude to demonstrate multiple perspectives. Furthermore, these characteristics of assessment (mainly regarding examinations) also emerged as a strand of culturally nuanced findings. Students explicitly regarded assessment influencing their epistemic beliefs and described how they differentiated their incongruent “professed” and “practised” epistemic beliefs so as to fit the rules of the public examination. The findings have yielded cultural implications and suggest the need to understand epistemic beliefs transcending the naive-sophisticated dichotomy.     

Energy Internet forums as acceleration phase transition intermediaries

Citizen users play important roles in the acceleration phase of energy transitions, during which small-scale renewable energy technologies (S-RET) become taken up more widely. From users’ perspective, turning the early, and typically slow, proliferation into a more rapid and widespread diffusion requires not only the adoption of S-RET but also the adaptation, adjustment, intermediation and advocacy of S-RETs. These activities become necessary because S-RET face a variety of market, institutional, cultural and environmental conditions in different countries. New Internet-based energy communities have emerged and acted as key user-side transition intermediaries that catalyse these activities by qualifying market information, articulating demand and helping citizen users to reconfigure the standard technology to meet the specificities of different local contexts. In doing so, Internet communities foster an appreciatively critical discourse on technology. Such user intermediation is important in expanding the markets for S-RET beyond that of enthusiasts, environmentalists and other early adopters, to the early majority of adopters who demand more exposure, clearer information and less uncertainty about new technology options.