药物高通量亲合色谱筛选中定性定量模型的建立

通过对AC高通量筛选过程的分析，建立了AC技术筛选药物的定性及定量模型，为高通量药物筛选提供了必要的理论指导。     

四种菊酯农药残留量的气相色谱分析

研究了用气相色谱分析白菜、甘蓝、黄瓜、土壤和水中氰戊菊酯、高氰戊菊酯、溴氰菊酯、顺式氯氰菊酯的残留量.样品用两酮-石油醚提取、石油醚萃取、弗罗里硅土-中性氧化铝柱净化后,用带~(63)Ni-ECD的气相色谱仪进行检测.上述四种菊酯在白菜、甘蓝、黄瓜中添加浓度0.01～2.00 mg/kg时回收率为81％～95％,在土壤中添加浓度 0.02～2.00 mg/kg时回收率为75％～81％.氰戊菊酯在水中添加浓度0.02～0.20 mg/L时回收率为 77％～97％.     

School quality, child wellbeing and parents’ satisfaction

Child wellbeing at school and enjoyment of the learning environment are important economic outcomes, in particular because a growing body of research shows they are strongly linked to later educational attainments and labour market success. However, the standard working assumption in the economics of education is that parents choose schools on the basis of test-score performance, and concerns about child happiness are largely ignored. In this paper, we address this omission and investigate to what extent parents’ and children's views of their school are linked to test-score based performance, and to what extent parents’ judgements of school quality are linked to their child's happiness. To do so, we use information on stated attitudes from the Longitudinal Survey of Young People in England (LSYPE) matched to administrative records on pupil achievements in England. Our results suggest that test-score based measures of school quality tend to dominate parental satisfaction with the learning environment. However, school quality along this dimension is not strongly associated with pupil happiness and wellbeing at school.     

Valuing the benefits of the education provided by public universities: A case study of Minnesota

This study estimates the value of the private and public benefits that accrue to Minnesota residents from state government subsidies to higher education. In 2005, the University of Minnesota and the Minnesota State Colleges and Universities system received $832 million from Minnesota's state government to support educational programs. These subsidies allow these institutions to offer lower tuition rates, increasing the number of Minnesotans with bachelor and graduate degrees. We calculate that removing these subsidies would eventually lead to 14,000 fewer graduate degree holders in Minnesota, and reduce those with bachelor's degrees or “some college” by 42,000. The annual economic cost of these subsidies is about $326 million; this is less than annual state appropriations because most of those appropriations are income transfers from taxpayers to students, not an economic cost. We estimate that the annual value of the benefits of these subsidies is between $531 and $786 million ($381 and $570 million) when a 3% (5%) discount rate is used. We also discuss some of the income distribution consequences.     

Does food insecurity at home affect non-cognitive performance at school? A longitudinal analysis of elementary student classroom behavior

This paper estimates models of the transitional effects of food insecurity experiences on children's non-cognitive performance in school classrooms using a panel of 4710 elementary students enrolled in 1st, 3rd, and 5th grade (1999-2003). In addition to an extensive set of child and household-level characteristics, we use information on U.S. counties to control for potential confounding effects of the local economic and noneconomic environment on children's household transitions between states of food insecurity and food security. The time horizon of our analysis affords insight into factors underlying children's formation of non-cognitive skills and the efficiency of classroom-based educational production in elementary school. Overall, we find significant negative developmental effects for children with food insecurity at home; and that children experiencing an early transition from food insecurity in 1st grade to food security in 3rd grade have even larger impairments that persist through 5th grade.     

Diagnostic Dilemma of HbA1c Detection in Presence of a Hemoglobinopathy: A Case Report

We report a case of a diabetic, heterozygote with near normal hematology, marginally low level of hemoglobin A₂(HbA₂) having an increased level of hemoglobin F(HbF) that was pancellularly distributed among the red cells. BioRad DiaSTAT measurements gave a high glycated hemoglobin A1c(HbA1c) of 31.5% and the BioRad Variant analyzer recorded an HbA1c value which was very low, in discordance with the detected blood glucose levels. Flow cytometry and polymerization chain reaction (PCR) based studies were carried out which revealed the case to be that of the common hereditary persistence of fetal hemoglobin (HPFH)-3, an Asian Indian mutation. Fructosamine estimation and HbA1c by Boronate affinity chromatography were able to resolve the discordant value detected and was able to confirm the diabetes status. The case would have been a diagnostic dilemma, if reported without correlation.     

基于气相色谱的电子鼻气体检测系统

论文基于色谱分离技术,叙述了一种新型传感器阵列组成的有机挥发物检测系统。利用气相色谱的分离效果对混合物质进行检测,具有抗干扰、便携等特点。通过传感器之间响应互补特性,可对多种物质进行测量。有效地解决了便携、选择性、快速等技术难题。通过对多种混合气体进行实验检测,证明了本系统的实用性。     

浅析气相色谱技术诊断变压器故障的应用

气相色谱技术能够对运行中的变压器进行实时监测,尽早发现变压器内部故障,因为变压器内部故障时变压器和发热气,中大部气中,通中气的及,变压器故障故障的及部。     

玉米须水煮液乙醚萃取物化学成分的研究

用乙醚对玉米须水煮液进行萃取,再利用气相色谱质谱联用仪进行成分分析,然后用谱峰面积归一化法测定各组分相对含量,结果共鉴定出23种化学成分,其中主要的化学成分有:邻二甲苯(含量为15.02%)、对二甲苯(含量为11.93%)、对乙烯基苯乙醚(含量为17.12%)、4,4-二甲基-1-氰基环已醇(含量为15.29%),(3反)-4-甲硫基丁烯基异氰酸酯。     

知母的化学成分提取分离方法

中药知母Anemarrhena asphodeloides Bge根茎的乙醇提取物，经大孔吸附树脂柱色谱脱糖、反复硅胶柱色分离、中压柱层析、反相硅胶柱层析分离得到了六个甾体皂甙类化合物，根据它们的理化性质和光谱（IR，FAB-MS，^1-H-NMR，1^13C-NMR）数据对它们的结构进行鉴定；分别为知母皂甙timosaponin A（Ⅰ），知母皂甙timosaponin B-Ⅱ（2），知母皂甙Anemarrhenasaponin-Ⅰ（3），西菱皂甙B Xilingsaponin B（5）化合物。且各自的提取分离条件不同，其纯度、产率也有差异。