浅谈纳米给药的现状,进展,问题和前景

通过文献中描述的药动学、毒理学研究结果得知纳米给药系统的特点及纳米给药系统在医药领域的应用中的优势,主要是在肿瘤治疗领域的作用,最后概括纳米给药系统的前景及展望。     

清热解毒法治疗玫瑰糠疹的临床观察

目的：探讨自拟中药清热解毒法治疗50例玫瑰糠疹的临床疗效。方法：将100例玫瑰糠疹患者随机分为中药治疗组50例和西药对照组50例。治疗组采用中药方剂清热解毒汤温热口服;对照组以西药治疗,用开瑞坦片10 mg/次,1次/d,口服;维生素C片100 mg/次,3次/d,口服。结果：治疗组有效率为94%,对照组为70%,二者差异有显著性（P〈0.05）。结论：清热解毒法治疗玫瑰糠疹有显著疗效。     

猪链球菌分离株的分群鉴定及药敏试验

2001至2003年,从安阳、邯郸等6个地区采取180份猪的病料,从中分离到50株链球菌,对其中20株典型分离株进行了生化分群鉴定、兰氏分群A—G诊断试剂鉴定和药敏试验。结果表明,6个地区发生的猪链球菌病主要由C群(6/20),D群(4/20),E群(5/20)和G群(2/20)链球菌引起,其分布无明显地域性。药敏试验结果表明,对环丙沙星、强力霉素等高度敏感,敏感菌株达95%以上,可作为防治猪链球菌病的首选药物。     

Drug prevention for young people with social,emotional and behavioural difficulties attending special education provision

The levels of drug use amongst school‐aged young people have risen over the past decade. Prevention initiatives have been developed using empirical evidence obtained from school‐based surveys. The empirical evidence base of drug use amongst young people with social, emotional and behavioural difficulties (SEBD) attending special education provision is very limited. The implications of this knowledge gap for addressing drug use amongst these young people are explored in this paper. Proposals for the way forward are suggested, for developing a framework for targeted evidence‐based interventions for young people attending emotional and behavioural difficulty units.     

Pathway to efficacy: Recognizing cognitive behavioral therapy as an underlying theory for adventure therapy

Abstract

This paper examines information on the histories, definitions, and components of adventure therapy and cognitive behavioral therapy to determine if cognitive behavioral therapy provides a theoretical basis upon which the efficacy of adventure therapy can be judged. It is found that adventure therapy and cognitive behavioral therapy share aspects including transformation of distorted thinking patterns, a focus on current and future functioning, consideration of the interrelationship between the counselor and the client, and understanding the use of stress as a part of the change process. By recognizing cognitive behavioral therapy as the empirically sound, underlying theory for adventure therapy researchers will be able to determine the effective components of therapy in the outdoors.     

黄冈职院附属医院抗菌药物应用情况分析

目的了解黄冈职院附属医院抗菌药物的使用情况,为规范医院使用抗菌药物提供依据。方法收集附属医院近三年来抗菌药物的用药品种、销售金额、使用频率,日均消费进行统计和分析。结果抗菌药物用药品种、金额、频率、日均消费、剂型较为规范,但国家基本药物抗菌药物品种的应用在逐年下降。结论附属医院对抗菌药物的临床应用基本合理,但是对国家基本药物应用的逐年下降趋势,应引起重视,及时调整。     

论齐梁药名诗

齐梁药名诗的出现标志着药名诗在诗歌史上的确立,它体现了诗歌发展过程中的一个必然阶段,推动了诗歌的成熟;反映了齐梁诗人的活动状况,展示了士人的学识素养;传播了学科知识,拓展了诗歌的功用。它用自身的形态和价值丰富了诗歌的百花园,是中华民族宝贵的文化遗产。     

数据挖掘技术在连锁药店管理中的应用研究

以亳州盖福祥连锁药店为例,利用关联规则对数据库中药品的销售信息进行挖掘及利用NK—means聚类算法对顾客忠诚度进行聚类分析研究,找出影响连锁药店盈利的主要因素,为连锁药店改进营销策略、提高服务质量提供参考依据。     

民族地区药管专业实训教学面临的困境与对策--以广西民族师范学院为例

实训教学是技能培养的重要组成部分,在人才培养过程中越来越发挥出它的重要作用。民族地区药管专业在实训过程中遇到了实训机会较少,市场容量有限、管理不到位,学生难以“走出去”,实训岗位单一化,实训效果难以考核等各种困境,因此,必须采取行之有效的对策,应用创新的眼光去摸索一种符合实际的实训教学模式,以提高药管专业的实训教学效果。     

Exploring adverse drug reactions of diabetes medicine using social media analytics and interactive visualizations

The aim of this study is to propose an automatic and real-time social media analytics framework with interactive data visualizations to support effective exploration of knowledge about adverse drug reaction (ADR) surveillance. This proposed framework has been prototypically implemented on the basis of social media data. A longitudinal diabetes patient online community data (AskaPatient.com) as well as FDA Adverse Event Reporting Systems (FAERS) data as a benchmark were used to evaluate our proposed approach’s performance. Based on the results, our approach significantly increases the precision and accuracy for ADR extraction. The number of ADR cases, the time when the ADRs occurred, and the rating of Glucophage have been visualized that resulted by mining a collection of 870 ADRs posted in Askapatents.com over a certain time period (from 2001 to 2015). The results have important implications for pharmaceutical companies and hospitals wishing to monitor ADRs of medicines.