6061-T5铝合金搅拌摩擦焊接头组织和力学性能

采用搅拌摩擦焊技术对6061-T5铝合金进行焊接,分析了焊接速度对接头成形、微观结构及力学性能的影响.结果表明:随着焊接速度的增加,沉淀相固溶度下降,晶粒细化;焊接速度过大时,热输入不足,呈现原始态组织.当转速为800 r/min,焊接速度为60 mm/min时,接头成形良好,抗拉强度达到最大值.采用合适的搅拌摩擦焊工艺参数,6061-T5铝合金能实现可靠的连接.     

[NbOF5]^2-的电子结构计算和键价计算

应用GAUSSIAN 03（DFT/B3LYP和HF两种方法）程序对游离（未参与桥联）的配阴离子[NbOF5]^2-的电子结构进行了理论计算,得到了其优化结构的键长和键角、Mulliken和NBO电荷布居、前沿分子轨道特征与能量及能级差、红外频率等参数．键价计算表明在此阴离子中氧和其反位的氟原子具有最多的负电荷,亲核性最强．     

“十五”期间国家社科基金项目的计量学研究

对“十五”国家社科基金项目的系统分布、时间分布、学科分布、地区分布等进行了调研分析，借以探讨我国社会科学研究的状况。经济学仍然是未来相当长时期内的研究热点，社科研究力量在系统、单位及地区的分布极不均衡，表现出很强的离散态势。国家在制定社科研究规划中，既要考虑重要基地建设，又要考虑其覆盖的范围，应“点”“面”结合，以“点”带“面”。     

乳腺癌耐受蛋白介导5-氟脲嘧啶的耐受及机制探讨

AIM To filtrate breast cancer resistance protein(BCRP)-mediated resistance agents and investigate the mechanism,so as to provide valuable datum for optimization clinical chemotherapy scheme to tumor with evaluation marker of BCRP expression. METHODS MTT assay was used to filtrate BCRP-mediated resistance agents with PA317/Tet-on/TRE-BCRP cell of different expression levels of BCRP after treated with different concentration anticancer agents. High performance liquid chromatography(HPLC) was applied to measure relative dose of intracellular retention resistance agents. Nuclear DNA fluorescence dye,Hochest 33258, staining and flow cytometry were adopted to detect apoptotic cells after treated with drugs. RESULTS There were shown increasing durg-resistance to 5-fluorouracil,methotrexate, doxirubicin, pirarubicin,etoposide and mitoxantrone followed with increasing expression of BCRP on PA317/Tet-on/TRE-BCRP cells(P＜0.05, n=3),but shown sensitive to paclitaxel, cisplatin, vincristine, mitomycin and vindesine. There also was shown significant negative correlation between the intracellular retention dose of 5-fluorouracil with different expression of BCRP(r=-0.885, P＜0.05, n=3).There were shown parallel results of that decreasing cellular apoptotic rate with increasing cellular expression of BCRP after treated with 5-fluorouracil by fluorescence dye staining and flow cytometry(P＜0.05, n=3),and also shown significate rise of the apoptotic rate of BCRP expression cells after treated with Ko143 (P＜0.05, n=3). Every group of cells could be different extently blocked in phase of G0/G1 treated with 5-fluorouracil. CONCLUSION Resistance of 5-fluorouracil could be especially mediated by conjugated with BCRP and acted as drug exclude-pump substrate. Cellular ability resistant to 5-fluorouracil-induced apoptosis could be reinforced by BCRP expression.     

利用概念图进行网络课程内容的设计研究

在简要介绍概念图和概念矩阵的基础上,以概念图和概念对知识体系表示的方法为依据,结合具体课程的结构,说明了构建网络课程教学内容的方法,并说明了该方法的优点。     

Forward Position Analysis of 5-DOF Parallel Mechanism

Forward position analysis is one of the importantand difficult issues in the kinematic analysis of paral-lel manipulators and has been extensively investiga-ted[1—3]. Most of the approaches for solving forwardposition problems of parallel manipulators with six de-grees of freedom (6-DOF), the Stewart platform forinstance, can be classified into two categories, i.e.closed-form analytical method using polynomial ap-proach and numerical method using iterative algo-rithm. Although the polynomial…     

聚合物支载的15-冠-5的合成

本研究给出高分子冠醚化合物的一种新合成方法——用烯丙氧基化的聚苯乙烯作为合成冠醚的前体，在NBS存在下与三缩四乙二醇加成，然后关环生成聚合物支载的15-冠-5。     

Beauty and Character: Values Beyond Beauty in Architecture

Formalist conceptions of aesthetic goals began to give way from the 17^th century on to rationalist accounts of experience. Beauty as described as essential by Renaissance thinkers was reconceived as just one possibility, with the sublime in Burke's account as another. In the early 20^th century Clive Bell again asserted a formalist position with his argument for significant form. The weakness of the formality position, and the need for a richer, more contextual account of aesthetic goals and experience is argued with reference to the idea of thick and thin concepts as applied by Bernard Williams to ethics, Wittgenstein's attention to the way in which language is used in a specific context, and Scruton's emphasis on an informed conception of the object of aesthetic attention. Beauty, in Alberti's procedural account if not in his version of the Platonic ideal, can be seen to continue to have critical value. The idea of character, however, offers a broader range of possibilities for experience and of goals for design.     

3,6-二甲基哒嗪的合成

为填补国内市场空白,以乙酰乙酸乙酯、钠为原料;通过关环、脱氢等反应,高产率地合成了3,6-二甲基哒嗪.该方法步骤短,收率高,是合成3,6-二甲基哒嗪的一种简捷方法.     

GPS现代化中L5的模拟

利用GPS三频及组合数据可以快速解求模糊度；能够更好地消除电离层、对流层的影响，且动态定位的可靠性较双频数据能够更好地满足精度的要求；研究了利用非差思想对L5进行数值模拟的方法．给出数值模拟结果并对其进行分析。