中国西北沙漠对东亚大气粉尘影响的数值试验研究

以塔克拉玛干沙漠为主的中国西北沙漠区是东亚地区主要沙尘释放源区之一。本文利用美国大气研究中心（NCAR）的公用气候模式（CCM3）与一个沙尘释放和沉降模式（DEAD）相嵌套、能够反映沙尘扬起及输送和沉降动态过程的耦合模式系统（CCM3-DEAD），通过改变中国西北沙漠-半沙漠区下垫面类型的数值模拟试验，对比分析了西北沙尘源区地表类型的改善对东亚地区沙尘释放及大气粉尘含量变化的可能影响。研究结果表明，地表覆盖状况与沙尘释放关系密切，沙尘源区地表类型的改善可明显抑制沙尘的释放。中国西北沙漠-半沙漠区地表的改善，可引起整个中国北方至蒙古国的大气粉尘含量减少，使大气环境明显改善。假设以塔克拉玛干为主的沙漠-半沙漠区不存在（当地地表类型若以温带草原植被为主），则整个中国北方沙尘释放和沉降通量仅为目前的50%左右。模式中分4个粒级描述沙尘释放及沉降通量，其中1.0~2.5μm和2.5~5.0μm两个粒级的贡献约占总通量的76%，对比试验显示在没有塔克拉玛干等沙漠存在的情况下这两个粒径释放通量大大降低。由西北沙漠-半沙漠区释放的沙尘，经大气环流传输可直接影响到我国东北、华北等东部地区的大气粉尘状况，并对日本、韩国及其周边地区也有一定影响。     

Lipid peroxide levels and antioxidant status in alcoholic liver disease

The present study was conducted to evaluate some of the components of antioxidant defense system and oxidative damage in 20 male patients of alcoholic liver disease (ALD). The results were compared with 20 healthy male smokers and 20 healthy male non-smokers volunteers. Patients were subjected to detailed clinical examination and laboratory investigations. Blood samples were collected for estimating reduced glutathione (GSH), total thiols (T-SH) malondialdehyde (MDA), transaminases (AST, ALT), glutathione-S-transferease (GST) and gammaglutamyl transferase (GGT). Serum aspartate amino transferase (AST)/alanine amino transferase (ALT) ratio was significantly (p<0.01) reduced in ALD patients as compared to the controls. However, the core of utility of MDA and GST was found to be significantly (p<0.01) increased in ALD patients compared to controls. There was a significant negative correlation of MDA with both GSH and TSH. Plasma GGT levels were significantly (p<0.01) increased in alcoholics and the enzyme showed a significant positive correlation with MDA. These results give enough evidence of increased oxidative stress and compromised antioxidant defense system in patients with ALD.     

脑科学与类脑研究概述

脑科学和类脑智能技术是两个重要的前沿科技领域;二者相互借鉴、相互融合的发展是近年来国际科学界涌现的新趋势。脑科学研究对大脑认知神经原理的认识,提升了人类对自身的理解和脑重大疾病的诊治水平,也为发展类脑计算系统和器件、突破传统计算机架构的束缚提供了重要的依据。文章概括性地总结了国际脑科学和智能技术领域的总体进展,未来15年的发展趋势和有望解决的重大科学问题,以及我国在这两领域发展的特色和优势。     

象山地区中国对虾白斑综合征病毒超微结构观察

从患病的中国对虾(Penaeus chinensis)头胸部分离提纯出一种杆状病毒,负染观察发现,病毒粒子的核衣壳呈杆状,大小约为(250～290) nm × (65～80) nm,每圈螺旋宽约20 nm,核衣壳的两个末端之间一般有13～15圈衣壳螺旋.个别病毒有较长的核衣壳,螺旋数达30圈,长度达到600 nm.有部分病毒核衣壳的一端有30～65 nm的凹陷.还有部分病毒核衣壳一端有30～60 nm的突出部分.     

血浆纤维蛋白原水平升高同高血压,冠心病及卒中的联系

选择46岁以上的高血压(HBP)、冠心病(CHD)、卒中及其它内科住院病人共140名进行了血浆纤维蛋白原(FG)、血压、甘油三酯(TG)和吸烟等因素的观察.结果表明高血压、冠心病和车中患者FG值升高,逐步回归分析看出吸烟,HBP和TG水平升高明显影响FG的含量,提示FG水平升高同HBP,CHD和年中存在着紧密的联系。     

基于LiDAR点云特征和模型拟合的高压线提取

高压线数字化是数字电网建设和线路智能巡检的核心内容,机载LiDAR在高压线三维数字重建中具有独特的优势。提出一种从输电走廊机载LiDAR点云数据自动快速高精度提取完整电力线点的方法。首先基于点云的空间分布特征粗提取电力线点,并通过改进Hough变换和RANSAC抛物线拟合法剔除噪点,然后分别进行电力线在平面和垂直面上的分股,结合单股电力线的平面直线模型和垂直面上的抛物线模型,采用模型生长的方法提取完整的电力线点。试验结果表明,该方法提取的电力线点云的精度可达99.6%。     

中国的人体组成学研究:回顾与展望

人体组成学是人体生物学的分支学科之一,主要研究人体内诸多组分的含量与分布、组分之间的数量关系、在活体中测定人体组分的方法、以及体内外各种因素对组分含量的影响。研究人体组成不仅具有生物学意义,也与提高国民体质、增进健康、治疗疾病密切相关。进入21世纪以来,海峡两岸对人体组成的研究呈快速发展的态势,每年平均发表58篇论文,约占全世界此领域论文总数的3.9%。这表明两岸的人体组成学研究,已在世界上占有一席之地。中国对人体组成的研究主要集中在3个方面：对中国人群身体组成特点的研究、对运动与身体组成关系的研究、以及对疾病与身体组成关系的研究。未来,两岸的人体组成研究应该在多方位发展,特别是研究更多的身体组分（如骨骼肌与内脏脂肪组织）、应用先进的测定方法、以及探讨黄种人的身体组成特点。第9届国际人体组成学研讨会于2011年在杭州举行,这必将进一步促进海峡两岸人体组成学研究的发展。     

Organic Acidurias: An Updated Review

Organic acidurias are an important class of inherited metabolic disorders arising due to defect in intermediary metabolic pathways of carbohydrate, amino acids and fatty acid oxidation. This review summarizes the current knowledge about the important organic acidurias in the Indian population. Specifically, diagnosis and principles of treatment of organic acidurias are covered. The salient features of common organic acidurias as well as their prevalence in various parts of the world are reviewed in some detail.     

Myeloperoxidase in Chronic Kidney Disease

Numerous lines of evidence implicate a role of myeloperoxidase (MPO) in the pathogenesis of cardiovascular disease (CVD). It is a well accepted fact that patients with chronic kidney disease (CKD) are at an increased risk for CVD. MPO is a pro-oxidant enzyme which could be involved in the increased susceptibility of these patients to CVD. Hence, the levels of plasma MPO was determined in healthy controls as well as in patients with CKD [stratified with the level of their kidney failure as CKD stages II–V (end stage renal disease)]. Plasma MPO was assayed by a spectrophotometric method. Serum urea and creatinine were estimated on a clinical chemistry analyzer using standard laboratory procedures. The mean plasma MPO levels were significantly lower with advancing stages of renal failure (P < 0.001). There was a positive correlation between MPO and GFR (r = +0.89, P < 0.001) and a negative correlation with urea (r = −0.85, P < 0.001) and creatinine (r = −0.82, P < 0.001). While an inverse association was observed between plasma MPO and urea in CKD patients, such an association was not observed in control subjects (P = 0.43). In conclusion, the decline in plasma MPO levels may be due to the inhibitory effect of uraemic toxins on the enzyme.     

网络环境下省疾控中心图书馆工作

网络环境下,疾控中心图书馆应围绕其职能特点提供服务,其建设目标是收集和提供信息资源、提高信息咨询能力、提供专题化信息服务和加强员工的培训,因此必须加强图书馆人才队伍建设。