多巴胺能药物对鲤鱼生长激素分泌活动的影响

研究多巴胺（Dopamine，DA）及其激动剂阿朴吗啡（Apomorphine，APO）、拮抗剂Domperidone（DOM）对不同性腺发育时期和不同年龄雌鲤生长激素（GH）分泌活动的影响．结果表明，鲤鱼基础GH分泌存在明显的季节性变化：性腺发育早期＜性肠成熟期＜性腺退化期．DA和APO刺激的GH分泌也存在明显的季节性变化：性腺发育早期＞性腺成熟期＞性腺退化期．DOM不影响性腺发有早期和性腺成熟期的GH分泌，但显著性降低性腺退化期的GH水平．6月龄鱼血清基础GH水平明显低于2～3龄和1龄鱼；不同年龄鱼对多巴胺能药物的反应性表现为：1龄色最强，2～3龄和6月龄鱼较弱．     

胃肠炎病死雌孔雀病理剖检一例

本文研究了雌孔雀胃肠炎的病理变化,指出此孔雀所患胃肠炎为非传染性疾病.     

2型糖尿病临床用药的正确选择

目的:探讨正确合理应用口服降糖药对2型糖尿病(T2DM)患者快速降低血糖(BG),降低T2DM并发症的临床意义.方法:2002.10～2004.10月河北北方学院(原张家口医学院)校医院门诊及住院108例T2DM患者治疗前及治疗5周后进行空腹血糖(FBG)、餐后血糖(PBG),糖化血红蛋白(HbA1c),尿白蛋白(ALB),尿酮体及血脂测定.结果:所有病患治疗5周后各项检测指标均较治疗前有明显改善.结论:正确合理用药对预防或延缓并发症出现有积极的意义.     

大鼠梗阻性黄疸对急性胃粘膜病变的影响及洛赛克对它的预防研究

通过制作大鼠 Ｏ Ｊ和 Ａ Ｇ Ｍ Ｌ 模型,研究了 Ｏ Ｊ对 Ａ Ｇ Ｍ Ｌ 的影响及洛赛克对 Ａ Ｇ Ｍ Ｌ 的预防作用．结果表明： Ｏ Ｊ能明显加强大鼠应激下 Ａ Ｇ Ｍ Ｌ 的形成,且其 Ａ Ｇ Ｍ Ｌ 的严重性与胆道梗阻时间相关,洛赛克对 Ｏ Ｊ大鼠应激下 Ａ Ｇ Ｍ Ｌ 的形成有预防作用     

强制戒毒的现制调整与合理定位——实施《禁毒法》的两大要点

随着《禁毒法》的实施,统一强制隔离戒毒的管理体制将促使劳教退出现制;戒毒的双重特性是绝大多数成瘾人员因吸毒过错负有接受治疗的义务,因脑部疾患拥有被治疗的权利;强制隔离旨在治疗而非惩戒或者贬损性教育,因而传统的管控模式须让位于真正意义上的治疗模式;但限于制度成本和客观可能,场所强戒应限于有治愈可能且具须与隔离的吸毒成瘾人员。     

‘Two's up and poncing fags’: young women's smoking practices,reciprocity and friendship

Over the past decade much has been written by journalists, policy makers, and academics, about young women's leisure time pursuits. A great deal of this interest has focused around a concern that teenage girls in the UK are taking up smoking in larger numbers than their male peers. This paper draws on findings from my small‐scale doctoral research into teenage girls' use of tobacco and alcohol in a town in southern England. I examine young women's use of cigarettes as an informal social currency, and as a way of thinking about such tobacco use beyond the deficit model of the young female smoker common to many drugs education interventions. In this paper I draw upon theoretical material from the social theories of exchange to explore how young women's reciprocal networks of cigarettes operate to underpin friendships and mobilise power within girls' social networks. I explore how smoking as a reciprocal gift‐giving practice supports and maintains friendship groups and particular gendered practices. My argument is that teen girls create and sustain bonds of friendship through their use and exchange of cigarettes. I want to suggest that within the girls' friendship groups, the flow of branded cigarettes as a resource highlights alliances, inter‐group rivalries, and provides space for the production and negotiation of teenage ‘cool’ femininities.     

The Coercion Argument Against Performance-Enhancing Drugs

This paper is a critique of the coercion argument against performance-enhancing drugs (PEDs). According to this argument, lifting the ban on PEDs would undermine the autonomy of athletes by creating a situation where everyone must either use PEDs or not compete at the highest levels of sport. Four problems are raised for this argument and it is concluded that the argument fails. A variation on the coercion argument is also considered and rejected.     

Dietary supplements

For the athlete training hard, nutritional supplements are often seen as promoting adaptations to training, allowing more consistent and intensive training by promoting recovery between training sessions, reducing interruptions to training because of illness or injury, and enhancing competitive performance. Surveys show that the prevalence of supplement use is widespread among sportsmen and women, but the use of few of these products is supported by a sound research base and some may even be harmful to the athlete. Special sports foods, including energy bars and sports drinks, have a real role to play, and some protein supplements and meal replacements may also be useful in some circumstances. Where there is a demonstrated deficiency of an essential nutrient, an increased intake from food or from supplementation may help, but many athletes ignore the need for caution in supplement use and take supplements in doses that are not necessary or may even be harmful. Some supplements do offer the prospect of improved performance; these include creatine, caffeine, bicarbonate and, perhaps, a very few others. There is no evidence that prohormones such as androstenedione are effective in enhancing muscle mass or strength, and these prohormones may result in negative health consequences, as well as positive drug tests. Contamination of supplements that may cause an athlete to fail a doping test is widespread.     

广西产十种有毒中药急性毒性实验研究

目的:观测小鼠依次口服大剂量曼陀罗、闹羊花、马钱子、斑蝥等10种广西产有毒中药的半数致死量,以评价其安全性。方法:每种中药在死亡率0%(Dn)和100%(Dm)范围内确定5～7个给药剂量,每个剂量组用20只小鼠进行观察7天,用Bliss法计算出半数致死量(LD50)等数据。结果:从半数致死量看,半夏的毒性在所有10种受试中药中最低;斑蝥毒性最高。毒性大小顺序为:斑蝥>蟾酥>马钱子>曼陀罗>闹羊花>木鳖子>山豆根>蛇床子>木通>半夏。结论:①多数受试有毒中药与药典标注的毒性程度基本相符;②根据不同毒性中药的半数致死量,可为中毒案件的侦破和定论提供科学的依据。     

The Health Risks of Doping during the Cold War: A Comparative Analysis of the Two Sides of the Iron Curtain

This article compares East Germany's Cold War-era approach to doping to that of the USA's in terms of their respective impacts on medical risk. Although deserving of criticism on many levels, the GDR doping programme featured a number of safeguards designed to minimise medical dangers. Unlike their East German counterparts, American governmental units were not directly involved in the administration of performance-enhancing substances. The US approach to doping was not ideal in terms of medical risk, however. As a result of the country's regulatory approach to doping, the country's athletes frequently turned to black market sources for doping agents. It was also relatively common for American athletes to use performance-enhancing drugs without the benefit of medical supervision. The US approach to doping was in these ways inferior to that of East Germany's on the subject of medical risk.