Utility of P-SEP,sTREM-1 and suPAR as Novel Sepsis Biomarkers in SARS-CoV-2 Infection

The coronavirus disease 2019 is a highly contagious viral infection caused by SARS-CoV-2 virus, member of coronaviridae family. It causes life threatening complications due to complexity and rapid onset course of the disease. Early identification of high-risk patients who require close monitoring and aggressive treatment remains challengeable till date. Novel biomarkers which help to identify high risk patients at the early stage is high priority. Objective of this review to find utility of P-SEP, sTREM-1 and suPAR for diagnosis, risk stratification and prognosis of SARS-CoV-2 infected cases. Soluble receptors like, P-SEP, sTREM-1 and suPAR have been involved in immune regulation in SARS-CoV-2 infection and elevate more in severe cases. A comprehensive research of databases like PubMed, EMBASE, CNKI and Web of Science was performed for relevant studies. A total of nine out of fifteen research literature in initial screening were included for this review. Interestingly all studies have reported high levels of P-SEP, sTREM-1 and suPAR in SARS-CoV-2 infected cases and the biomarkers positively correlated with severity of infection. This implies that P-SEP, sTREM-1 and suPAR can be implemented as surrogate marker in blood profile for early diagnosis, risk stratification and prognosis in SARS-CoV-2 for better management in Indian population at the current situation.     

下一代数字图书馆系统体系架构的发展动向

文章介绍了国外近年来下一代数字图书馆系统体系架构研究的新动向,着重分析了SOA、网格和P2P技术在数字图书馆领域内应用的研究及所开发的原型系统.     

中国经济空间格局演变及其CO2排放效应

改革开放以来,中国经历了由东部率先发展到区域协调发展的区域战略调整,中国经济空间格局发生较大改变.探究CO2排放量对经济空间格局演变的响应,对中国尽早实现CO2排放达峰目标、确保可持续发展具有重要意义.本文在刻画1985-2017年中国经济空间格局演变特征的基础上,基于LMDI因素分解方法分析了中国CO2排放的驱动因素...     

ONP脱墨浆的可漂性研究

ONP脱墨浆往往需要进一步漂白。对5种用不同脱墨剂处理的ONP脱墨浆进行了H2O2漂白实验,结果表明不同脱墨剂处理的ONP白度增加幅度不相同,各脱墨浆的可漂性并不相同。实际使用ONP脱墨浆时需考虑其漂后白度增幅潜力。     

NiCo_2O_4纳米结构阵列的水热合成与氧析出特性研究

钴酸镍纳米材料具有良好的电催化氧析出反应(Oxygen Evolution Reaction,OER)活性,是一种很有发展潜力的非贵金属电催化材料。文章以碳纤维纸为基底,采用水热合成的方法对纳米结构钴酸镍的生长进行了系统的研究,分别考察了生长温度、前驱体浓度和配比、生长时间对产物的形貌、尺寸、物相结构、OER电化学性能的影响,通过对比分析后发现在生长温度100℃、生长时间5h、镍钴比为2:1时所获得的多孔片状钴酸镍纳米结构具有最佳的OER特性。     

一种基于模糊语言TOPSIS的应急决策方法

在应急决策过程中,决策信息通常具有犹豫性、模糊性和非对称性,且决策者呈现出直观、快速的语言决策偏好。提出一种基于模糊语言TOPSIS的应急决策方法,使用犹豫模糊语言术语集和二元语义表达式对高度不确定环境下的语言进行处理,提高对犹豫模糊语言信息的提取能力,生成易于理解的语言评估结果,从而辅助决策者进行快速、准确的决策判断。案例证实该方法的可行性与有效性,为解决应急决策问题提供了一种新方法。     

Responses to oral glucose challenge differ by physical activity volume and intensity: A pilot study

BackgroundOne-hour postprandial hyperglycemia is associated with increased risk of type 2 diabetes and cardiovascular disease. Physical activity (PA) has short-term beneficial effects on post-meal glucose response. This study compared the oral glucose tolerance test results of 3 groups of people with habitually different levels of PA.MethodsThirty-one adults without diabetes (age 25.9 ± 6.6 years; body mass index 23.8 ± 3.8 kg/m²; mean ± SD) were recruited and divided into 3 groups based on self-reported PA volume and intensity: low activity < 30 min/day of moderate-intensity activity (n = 11), moderately active ≥ 30 min/day of moderate-intensity PA (n = 10), and very active ≥ 60 min/day of PA at high intensity (n = 10). Participants completed an oral glucose tolerance test (50 g glucose) with capillary blood samples obtained at baseline, 15 min, 30 min, 45 min, 60 min, 90 min, and 120 min post-ingestion.ResultsThere were no significant differences between groups for age or body fat percentage or glycated hemoglobin (p > 0.05). The groups were significantly different in terms of baseline glucose level (p = 0.003) and, marginally, for gender (p = 0.053) and BMI (p = 0.050). There was a statistically significant effect of PA on the 1-h postprandial glucose results (p = 0.029), with differences between very active and low activity groups (p = 0.008) but not between the moderately active and low activity groups (p = 0.360), even when baseline glucose level and gender differences were accounted for. For incremental area under the curve there was no significant effect of activity group once gender and body fat percentage had been accounted for (p = 0.401). Those in the low activity group took 15 min longer to reach peak glucose level than those in the very active group (p = 0.012).ConclusionThe results suggest that high levels of PA have a beneficial effect on postprandial blood glucose profiles when compared to low and moderate levels of activity.     

面向智能制造的汽车企业c2B模式实施策略

基于新技术条件下汽车产业形态的变化趋势,分析汽车产业走向c2B模式的必然性。根据汽车产业c2B模式的发展过程特征,对其作初级、中级、高级3个不同阶段的划分,并分析该模式对汽车全生命周期各环节的影响;通过对比汽车企业c2B模式的理想状态与现实状况,总结汽车企业c2B模式的关键实现环节,并进一步归纳整车厂和零部件企业需要满足的条件。从汽车产业c2B模式与智能工厂相互交融、互为支撑的关系,分析面向智能制造进行c2B模式建设所需的硬件、软件工作;以典型整车企业为例,提出汽车企业面向智能制造进行c2B模式升级的实施策略。     

利用DOI识别科技期刊官方网站的意义与方法

摘 要 【目的】保证科技期刊官方网站的有效识别与永久链接,扩大官网的网络影响力,为解决非法网站假冒期刊官网、欺骗作者、读者的问题提供途径。【方法】 利用DOI标准与技术以及中文DOI相关服务,对期刊网站进行DOI唯一标识的注册,并通过DOI解析实现方便、持久的网络链接;利用纸刊印刷二维码等方式实现纸刊与期刊网站的连接。【结果】 有效防御假冒伪劣期刊网站对正规网站的侵害;实现科技期刊多种传播渠道的协同增效作用。【结论】 为期刊网站注册DOI标识保护了读者、作者和期刊编辑出版单位的权益,扩大了科技期刊官方影响力,应大力推广。     

中国碳排放区域格局变化与减排途径分析

作为世界能源消费大国,中国的碳排放问题不仅体现在总量增长方面,而且也体现在碳排放的空间格局变化方面。从大区地域系统变化来看:东部地区的碳排放始终在全国占据着主导地位;中部地区碳排放在全国的比重表现出稳中有降的态势;西部地区比重虽较小,但基本保持着上升趋势。从省(区、市)级变化来看:1953年以来,碳排放的区域差异不断增大,并且其变化可以分为3个阶段:1952年为起始阶段、1953年-1980年为初级分化阶段、1981年-2005年为快速演进阶段。本文试图通过产业-能源关联和能源-碳排放关联两个基本评价模型,解析中国碳排放区域格局变化的原因。分析结果表明:①产业结构的演进决定着一次能源消费的基本空间格局;②地区产业结构多元化程度越是走向成熟,其一次能源消费的增速也就越是减缓;③缓慢的一次能源消费结构变化是难以降低地区碳排放增长的关键所在。因此,加快产业结构演进速率以逐步减缓地区一次能源消费总量增长,以及最大限度地改善各地区、特别是东部地区的一次能源供应结构,是有效控制区域碳排放增长的关键。